TopFIND 4.0

F4K2A1: Folylpolyglutamate synthase {ECO:0000250|UniProtKB:Q05932, ECO:0000312|EMBL:CAC80839.2}

General Information

Protein names
- Folylpolyglutamate synthase {ECO:0000250|UniProtKB:Q05932, ECO:0000312|EMBL:CAC80839.2}
- 6.3.2.17 {ECO:0000269|PubMed:11752472}
- DHFS-FPGS homolog B {ECO:0000312|EMBL:AED90949.1}
- Folylpoly-gamma-glutamate synthetase {ECO:0000250|UniProtKB:Q05932}
- FPGS {ECO:0000250|UniProtKB:Q05932}
- Tetrahydrofolylpolyglutamate synthase {ECO:0000250|UniProtKB:Q05932}
- Tetrahydrofolate synthase {ECO:0000250|UniProtKB:Q05932}
Gene names FPGS1
Organism Arabidopsis thaliana
Protease Family
Protease ID
Chromosome location
UniProt ID F4K2A1

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MFAVSIVPRT TSCRLSSAFL CQLSIPLTLR LHHHYQHHQP HLPSPLSFQI HSLRKQIDMA 
        70         80         90        100        110        120 
AQGGDSYEEA LAALSSLITK RSRADKSNKG DRFELVFDYL KLLDLEEDIL KMNVIHVAGT 
       130        140        150        160        170        180 
KGKGSTCTFT ESIIRNYGFR TGLFTSPHLI DVRERFRLDG VDISEEKFLG YFWWCYNRLK 
       190        200        210        220        230        240 
ERTNEEIPMP TYFRFLALLA FKIFAAEEVD AAILEVGLGG KFDATNAVQK PVVCGISSLG 
       250        260        270        280        290        300 
YDHMEILGDT LGKIAGEKAG IFKLGVPAFT VPQPDEAMRV LEEKASETEV NLEVVQPLTA 
       310        320        330        340        350        360 
RLLSGQKLGL DGEHQYVNAG LAVSLASIWL QQIGKLEVPS RTQMSILPEK FIKGLATASL 
       370        380        390        400        410        420 
QGRAQVVPDQ YTESRTSGDL VFYLDGAHSP ESMEACAKWF SVAVKGDNQS GSSGHLVNGS 
       430        440        450        460        470        480 
AGSSHDKWSN ETCEQILLFN CMSVRDPNLL LPHLKNMCAK YGVNFKKALF VPNMSVYHKV 
       490        500        510        520        530        540 
GTAADLPEND PQVDLSWQFT LQKVWESLVQ SERDGEKDGE SDGNSEVFTS LPMAIKCLRD 
       550        560        570    
TVHESSSATR FQVLVTGSLH LVGDVLRLIR K

Isoforms

- Isoform 2 of Folylpolyglutamate synthase

Sequence View

        10         20         30         40         50         60 
MFAVSIVPRT TSCRLSSAFL CQLSIPLTLR LHHHYQHHQP HLPSPLSFQI HSLRKQIDMA 
        70         80         90        100        110        120 
AQGGDSYEEA LAALSSLITK RSRADKSNKG DRFELVFDYL KLLDLEEDIL KMNVIHVAGT 
       130        140        150        160        170        180 
KGKGSTCTFT ESIIRNYGFR TGLFTSPHLI DVRERFRLDG VDISEEKFLG YFWWCYNRLK 
       190        200        210        220        230        240 
ERTNEEIPMP TYFRFLALLA FKIFAAEEVD AAILEVGLGG KFDATNAVQK PVVCGISSLG 
       250        260        270        280        290        300 
YDHMEILGDT LGKIAGEKAG IFKLGVPAFT VPQPDEAMRV LEEKASETEV NLEVVQPLTA 
       310        320        330        340        350        360 
RLLSGQKLGL DGEHQYVNAG LAVSLASIWL QQIGKLEVPS RTQMSILPEK FIKGLATASL 
       370        380        390        400        410        420 
QGRAQVVPDQ YTESRTSGDL VFYLDGAHSP ESMEACAKWF SVAVKGDNQS GSSGHLVNGS 
       430        440        450        460        470        480 
AGSSHDKWSN ETCEQILLFN CMSVRDPNLL LPHLKNMCAK YGVNFKKALF VPNMSVYHKV 
       490        500        510        520        530        540 
GTAADLPEND PQVDLSWQFT LQKVWESLVQ SERDGEKDGE SDGNSEVFTS LPMAIKCLRD 
       550        560        570    
TVHESSSATR FQVLVTGSLH LVGDVLRLIR K



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    F4K2A1-1-unknown MFAVSI... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    F4K2A1-59-unknown MAAQGG... 59 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt75425

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RLIRK 571 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...RLIRK 571 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt71043

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)