O00189: AP-4 complex subunit mu-1 {ECO:0000305}

General Information

Protein names	- AP-4 complex subunit mu-1 {ECO:0000305} - AP-4 adaptor complex mu subunit - Adaptor-related protein complex 4 subunit mu-1 - Mu subunit of AP-4 - Mu-adaptin-related protein 2 - mu-ARP2 - Mu4-adaptin - mu4
Gene names	AP4M1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O00189

4 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MISQFFILSS KGDPLIYKDF RGDSGGRDVA ELFYRKLTGL PGDESPVVMH HHGRHFIHIR
        70         80         90        100        110        120
HSGLYLVVTT SENVSPFSLL ELLSRLATLL GDYCGSLGEG TISRNVALVY ELLDEVLDYG
       130        140        150        160        170        180
YVQTTSTEML RNFIQTEAVV SKPFSLFDLS SVGLFGAETQ QSKVAPSSAA SRPVLSSRSD
       190        200        210        220        230        240
QSQKNEVFLD VVERLSVLIA SNGSLLKVDV QGEIRLKSFL PSGSEMRIGL TEEFCVGKSE
       250        260        270        280        290        300
LRGYGPGIRV DEVSFHSSVN LDEFESHRIL RLQPPQGELT VMRYQLSDDL PSPLPFRLFP
       310        320        330        340        350        360
SVQWDRGSGR LQVYLKLRCD LLSKSQALNV RLHLPLPRGV VSLSQELSSP EQKAELAEGA
       370        380        390        400        410        420
LRWDLPRVQG GSQLSGLFQM DVPGPPGPPS HGLSTSASPL GLGPASLSFE LPRHTCSGLQ
       430        440        450
VRFLRLAFRP CGNANPHKWV RHLSHSDAYV IRI

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Protease Assignment Confidence:

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Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O00189-1-unknown	MISQFF...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O00189-129-unknown	MLRNFI...	129	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000406676
O00189-151-	SVGLFG...	151		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
O00189-249-unknown	RVDEVS...	249	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000391585

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DRGSGR	309	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000414286
...SGLFQM	379	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000401613
...YVIRI	453	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)