TopFIND 4.0

O00221: NF-kappa-B inhibitor epsilon

General Information

Protein names
- NF-kappa-B inhibitor epsilon
- NF-kappa-BIE
- I-kappa-B-epsilon
- IkB-E
- IkB-epsilon
- IkappaBepsilon
Gene names NFKBIE
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID O00221

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MNQRRSESRP GNHRLQAYAE PGKGDSGGAG PLSGSARRGR GGGGAIRVRR PCWSGGAGRG 
        70         80         90        100        110        120 
GGPAWAVRLP TVTAGWTWPA LRTLSSLRAG PSEPHSPGRR PPRAGRPLCQ ADPQPGKAAR 
       130        140        150        160        170        180 
RSLEPDPAQT GPRPARAAGM SEARKGPDEA EESQYDSGIE SLRSLRSLPE STSAPASGPS 
       190        200        210        220        230        240 
DGSPQPCTHP PGPVKEPQEK EDADGERADS TYGSSSLTYT LSLLGGPEAE DPAPRLPLPH 
       250        260        270        280        290        300 
VGALSPQQLE ALTYISEDGD TLVHLAVIHE APAVLLCCLA LLPQEVLDIQ NNLYQTALHL 
       310        320        330        340        350        360 
AVHLDQPGAV RALVLKGASR ALQDRHGDTA LHVACQRQHL ACARCLLEGR PEPGRGTSHS 
       370        380        390        400        410        420 
LDLQLQNWQG LACLHIATLQ KNQPLMELLL RNGADIDVQE GTSGKTALHL AVETQERGLV 
       430        440        450        460        470        480 
QFLLQAGAQV DARMLNGCTP LHLAAGRGLM GISSTLCKAG ADSLLRNVED ETPQDLTEES 
       490        500    
LVLLPFDDLK ISGKLLLCTD 

Isoforms



Sequence View



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(REFRESH)

Directness:


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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LLCTD 500 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)