O00762: Ubiquitin-conjugating enzyme E2 C

General Information

Protein names	- Ubiquitin-conjugating enzyme E2 C - 2.3.2.23 {ECO:0000269\|PubMed:18485873, ECO:0000269\|PubMed:20061386} - (E3-independent) E2 ubiquitin-conjugating enzyme C - 2.3.2.24 {ECO:0000269\|PubMed:17588522} - E2 ubiquitin-conjugating enzyme C - UbcH10 - Ubiquitin carrier protein C - Ubiquitin-protein ligase C
Gene names	UBE2C
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O00762

7 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Ubiquitin-conjugating enzyme E2 C - Isoform 3 of Ubiquitin-conjugating enzyme E2 C - Isoform 4 of Ubiquitin-conjugating enzyme E2 C

Sequence View

        10         20         30         40         50         60
MASQNRDPAA TSVAAARKGA EPSGGAARGP VGKRLQQELM TLMMSGDKGI SAFPESDNLF
        70         80         90        100        110        120
KWVGTIHGAA GTVYEDLRYK LSLEFPSGYP YNAPTVKFLT PCYHPNVDTQ GNICLDILKE
       130        140        150        160        170
KWSALYDVRT ILLSIQSLLG EPNIDSPLNT HAAELWKNPT AFKKYLQETY SKQVTSQEP         10         20         30         40         50         60
MASQNRDPAA TSVAAARKGA EPSGGAARGP VGKRLQQELM TLMMSGDKGI SAFPESDNLF
        70         80         90        100        110        120
KWVGTIHGAA GTVYEDLRYK LSLEFPSGYP YNAPTVKFLT PCYHPNVDTQ GNICLDILKE
       130        140        150        160        170
KWSALYDVRT ILLSIQSLLG EPNIDSPLNT HAAELWKNPT AFKKYLQETY SKQVTSQEP         10         20         30         40         50         60
MASQNRDPAA TSVAAARKGA EPSGGAARGP VGKRLQQELM TLMMSGDKGI SAFPESDNLF
        70         80         90        100        110        120
KWVGTIHGAA GTVYEDLRYK LSLEFPSGYP YNAPTVKFLT PCYHPNVDTQ GNICLDILKE
       130        140        150        160        170
KWSALYDVRT ILLSIQSLLG EPNIDSPLNT HAAELWKNPT AFKKYLQETY SKQVTSQEP

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

7 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O00762-2-unknown	MASQNR...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O00762-1-unknown	MASQNR...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt93595
O00762-1-unknown	MASQNR...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt93596
O00762-2-Acetylation	ASQNRD...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O00762-2-Acetylation	ASQNRD...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110743
O00762-2-Acetylation	ASQNRD...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110744
O00762-18-unknown	KGAEPS...	18		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt164738
O00762-18-unknown	KGAEPS...	18		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt164739
O00762-18-	KGAEPS...	18			Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
O00762-40-unknown	MTLMMS...	40		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt93594
O00762-40-unknown	MTLMMS...	40		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt104565
O00762-44-unknown	MSGDKG...	44		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
O00762-44-unknown	MSGDKG...	44		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt195989
O00762-44-unknown	MSGDKG...	44		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt195988

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TSQEP	179	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...TSQEP	179	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt89212
...TSQEP	179	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt89213
...TSQEP	179	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt89214

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)