TopFIND 4.0

O08623: Sequestosome-1

General Information

Protein names
- Sequestosome-1
- Protein kinase C-zeta-interacting protein
- PKC-zeta-interacting protein
- Ubiquitin-binding protein p62
Gene names Sqstm1
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID O08623

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MASLTVKAYL LGKEEAAREI RRFSFCFSPE PEAEAAAGPG PCERLLSRVA VLFPALRPGG 
        70         80         90        100        110        120 
FQAHYRDEDG DLVAFSSDEE LTMAMSYVKD DIFRIYIKEK KECRREHRPP CAQEARSMVH 
       130        140        150        160        170        180 
PNVICDGCNG PVVGTRYKCS VCPDYDLCSV CEGKGLHREH SKLIFPNPFG HLSDSFSHSR 
       190        200        210        220        230        240 
WLRKLKHGHF GWPGWEMGPP GNWSPRPPRA GDGRPCPTAE SASAPSEDPN VNFLKNVGES 
       250        260        270        280        290        300 
VAAALSPLGI EVDIDVEHGG KRSRLTPTSA ESSSTGTEDK SGTQPSSCSS EVSKPDGAGE 
       310        320        330        340        350        360 
GPAQSLTEQM KKIALESVGQ PEELMESDNC SGGDDDWTHL SSKEVDPSTG ELQSLQMPES 
       370        380        390        400        410        420 
EGPSSLDPSQ EGPTGLKEAA LYPHLPPEAD PRLIESLSQM LSMGFSDEGG WLTRLLQTKN 
       430    
YDIGAALDTI QYSKHPPPL

Isoforms

- Isoform 2 of Sequestosome-1 - Isoform 3 of Sequestosome-1

Sequence View

        10         20         30         40         50         60 
MASLTVKAYL LGKEEAAREI RRFSFCFSPE PEAEAAAGPG PCERLLSRVA VLFPALRPGG 
        70         80         90        100        110        120 
FQAHYRDEDG DLVAFSSDEE LTMAMSYVKD DIFRIYIKEK KECRREHRPP CAQEARSMVH 
       130        140        150        160        170        180 
PNVICDGCNG PVVGTRYKCS VCPDYDLCSV CEGKGLHREH SKLIFPNPFG HLSDSFSHSR 
       190        200        210        220        230        240 
WLRKLKHGHF GWPGWEMGPP GNWSPRPPRA GDGRPCPTAE SASAPSEDPN VNFLKNVGES 
       250        260        270        280        290        300 
VAAALSPLGI EVDIDVEHGG KRSRLTPTSA ESSSTGTEDK SGTQPSSCSS EVSKPDGAGE 
       310        320        330        340        350        360 
GPAQSLTEQM KKIALESVGQ PEELMESDNC SGGDDDWTHL SSKEVDPSTG ELQSLQMPES 
       370        380        390        400        410        420 
EGPSSLDPSQ EGPTGLKEAA LYPHLPPEAD PRLIESLSQM LSMGFSDEGG WLTRLLQTKN 
       430    
YDIGAALDTI QYSKHPPPL         10         20         30         40         50         60 
MASLTVKAYL LGKEEAAREI RRFSFCFSPE PEAEAAAGPG PCERLLSRVA VLFPALRPGG 
        70         80         90        100        110        120 
FQAHYRDEDG DLVAFSSDEE LTMAMSYVKD DIFRIYIKEK KECRREHRPP CAQEARSMVH 
       130        140        150        160        170        180 
PNVICDGCNG PVVGTRYKCS VCPDYDLCSV CEGKGLHREH SKLIFPNPFG HLSDSFSHSR 
       190        200        210        220        230        240 
WLRKLKHGHF GWPGWEMGPP GNWSPRPPRA GDGRPCPTAE SASAPSEDPN VNFLKNVGES 
       250        260        270        280        290        300 
VAAALSPLGI EVDIDVEHGG KRSRLTPTSA ESSSTGTEDK SGTQPSSCSS EVSKPDGAGE 
       310        320        330        340        350        360 
GPAQSLTEQM KKIALESVGQ PEELMESDNC SGGDDDWTHL SSKEVDPSTG ELQSLQMPES 
       370        380        390        400        410        420 
EGPSSLDPSQ EGPTGLKEAA LYPHLPPEAD PRLIESLSQM LSMGFSDEGG WLTRLLQTKN 
       430    
YDIGAALDTI QYSKHPPPL



Filter Information:


(REFRESH)

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Evidence Codes:


Methodology:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


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Lab:



Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...HPPPL 439 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...HPPPL 439 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt153483

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)