TopFIND 4.0

O08662: Phosphatidylinositol 4-kinase alpha

General Information

Protein names
- Phosphatidylinositol 4-kinase alpha
- PI4-kinase alpha
- PI4K-alpha
- PtdIns-4-kinase alpha
- 2.7.1.67 {ECO:0000269|PubMed:8662589}
Gene names Pi4ka
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID O08662

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAAAGARGTG GSGSSSGSST SRGFYFNTVL SLARSLAVQR PASLEKVQKL LCMCPVDFHG 
        70         80         90        100        110        120 
IFQLDERRRD AVIALGIFLI ESDLQHKDCI VPYLLRLLRG LPKVYWVEES TARKGRGNLP 
       130        140        150        160        170        180 
VAESFSFCLV TLLSDVACRD PSLRDEILEA LLQVLHVLLG MCQALEIQEK EYLCKYAIPC 
       190        200        210        220        230        240 
LIGISRSFGR YSNSEESLLS KLFPKVPPHS LRIPEELEGV RRRSFNDFRS ILPSNLLTVC 
       250        260        270        280        290        300 
QEGTLKRKTS SVSSISQVSP ERGMPPPSSP GGSAFHYFEA SCLPDGTTLE PEYYFSTISS 
       310        320        330        340        350        360 
SFSVSPLFNG ITYKEFYIPL EMLRELLNLV KKIVEEPVLK SLDAAVARVM EANPSADLYY 
       370        380        390        400        410        420 
TTFSDPVYLT MFKMLRDTLY YMKDLPTSFV KEIHDFVLEQ FNMSQGELQK ILHDADRIHS 
       430        440        450        460        470        480 
EMSPLKLRCQ ANAACVDLMV WAVKDEQGAE NLCIKLSEKL QSKTSSKVII AHLPLLICCL 
       490        500        510        520        530        540 
QGLGRLCERF PVVVHSVTPS LRDFLVIPSP VLVKLYKYHS QYHTVAGSDI KISVTNEHSE 
       550        560        570        580        590        600 
STLNVLPGKK NQPSMYEQLR DIAIDNICRC LKAGLTVDPV IVEAFLASLS NRLYISQESD 
       610        620        630        640        650        660 
KDAHLIPDHT IRALGHIAVA LRDTPKVMEP ILQILQQKFC QPPSPLDVLI IDQLGCLVIT 
       670        680        690        700        710        720 
GNQYIYQEVW NLFQQISVKA SSVVYSATKD YKDHGYRHCS LAVINALANI AANIQEEHLV 
       730        740        750        760        770        780 
DELLMNLLEL FVQLGLEGKR ASERASEKGP ALKASSSAGN LGVLIPVIAV LTRRLPPIKE 
       790        800        810        820        830        840 
AKPRLQKLFR DFWLYSVLMG FAVEGSGLWP EEWYEGVCEI ATKSPLLTFP SKEPLRSVLQ 
       850        860        870        880        890        900 
YNSAMKNDTV TPAELNELRS TIINLLDPPP EVSALINKLD FAMSTYLLSV YRLEYMRVLR 
       910        920        930        940        950        960 
STDPDRFQVM FCYFEDKAIQ KDKSGMMQCV IAVADKVFDA FLNMMAEKAK TKENEEELER 
       970        980        990       1000       1010       1020 
HAQFLLVNFN HIHKRIRRVA DKYLSGLVDK FPHLLWSGTV LKTMLDILQT LSLSLSADIH 
      1030       1040       1050       1060       1070       1080 
KDQPYYDIPD APYRITVPDT YEARESIVKD FAARCGMILQ EAMKWAPTVT KSHLQEYLNK 
      1090       1100       1110       1120       1130       1140 
HQNWVSGLSQ HTGLAMATES ILHFAGYNKQ NTTLGVTQLT ERPACVKKDY SNFMASLNLR 
      1150       1160       1170       1180       1190       1200 
NRYAGEVHGM IRFSGATGQM SDLNKMMVQD LITALDHSHP QHYTQAMFKL TAMLISSKDC 
      1210       1220       1230       1240       1250       1260 
DPQLLHHLCW GPLRMFNEHG METALACWEW LLAGKNGVEV PFMREMAGAW HMTVEQKFGL 
      1270       1280       1290       1300       1310       1320 
FSAETKEADP LAASEASQPR PCPPEVTPHY IWIDFLVQRF EIAKYCSSDQ VEIFSSLLQR 
      1330       1340       1350       1360       1370       1380 
SMSLHIGGAR GSMNRHVAAI GPRFKLLTLG LSLLHADVVP NATIRNVLRE KIYSTAFDYF 
      1390       1400       1410       1420       1430       1440 
SCPPKFPTQG EKRLREDISI MIKFWTAMFS DKKYLTASQL VPPDNQDTRS NLDITVGSRQ 
      1450       1460       1470       1480       1490       1500 
QATQGWINTY PLSSGMSTIS KKSGMSKKTN RGSQLHKYYM KRRTLLLSLL ATEIERLITW 
      1510       1520       1530       1540       1550       1560 
YNPLSAPELE LDQAGENSVA NWRSKYISLS EKQWKDNVNL AWTISPYLAV QLPARFKNTE 
      1570       1580       1590       1600       1610       1620 
AIGNEVTRLV RLDPGAVSDV PEAIKFLVTW HTIDADAPEL SHVLCWAPTD PPTGLSYFSS 
      1630       1640       1650       1660       1670       1680 
MYPPHPLTAQ YGVKVLRSFP PDAILFYIPQ IVQALRYDKM GYVREYILWA AAKSQLLAHQ 
      1690       1700       1710       1720       1730       1740 
FIWNMKTNIY LDEEGHQKDP DIGDLLEQLV EEITGSLSGP AKDFYQREFD FFNKITNVSA 
      1750       1760       1770       1780       1790       1800 
IIKPYPKGDE RKKACLSALS EVKVQPGCYL PSNPEAIVLD IDYKSGTPMQ SAAKAPYLAK 
      1810       1820       1830       1840       1850       1860 
FKVKRCGVSE LEKEGLQCRS DTEDECRRQE ADGKKICWQA AIFKVGDDCR QDMLALQIID 
      1870       1880       1890       1900       1910       1920 
LFKNIFQLVG LDLFVFPYRV VATAPGCGVI ECIPDCTSRD QLGRQTDFGM YDYFTRQYGD 
      1930       1940       1950       1960       1970       1980 
ESTLAFQQAR YNFIRSMAAY SLLLFLLQIK DRHNGNIMLD KKGHIIHIDF GFMFESSPGG 
      1990       2000       2010       2020       2030       2040 
NLGWEPDIKL TDEMVMIMGG KMEATPFKWF MEMCVRGYLA VRPYMDAVVS LVTLMLDTGL 
      2050       2060       2070       2080       2090    
PCFRGQTIKL LKHRFSPNMT EREAANFIMK IIQNCFLSNR SRTYDMIQYY QNDIPY

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O08662-1-unknown MAAAGA... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...DTGLPC 2041 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)