O08796: Eukaryotic elongation factor 2 kinase

General Information

Protein names	- Eukaryotic elongation factor 2 kinase - eEF-2 kinase - eEF-2K - 2.7.11.20 {ECO:0000269\|PubMed:9144159} - Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase
Gene names	Eef2k
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	O08796

2 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MADEDLIFCL EGVDGGRCSR AGHNADSDTD SDDDEGYFIC PITDDHMSNQ NVSSKVQSYY
        70         80         90        100        110        120
SNLTKTECGS TGSPASSFHF KEAWKHAIEK AKHMPDPWAE FHLEDIATEH ATRHRYNAVT
       130        140        150        160        170        180
GEWLKDEVLI KMASQPFGRG AMRECFRTKK LSNFLHAQQW KGASNYVAKR YIEPVDRSVY
       190        200        210        220        230        240
FEDVQLQMEA KLWGEDYNRH KPPKQVDIMQ MCIIELKDRP GQPLFHLEHY IEGKYIKYNS
       250        260        270        280        290        300
NSGFVRDDNI RLTPQAFSHF TFERSGHQLI VVDIQGVGDL YTDPQIHTEK GTDFGDGNLG
       310        320        330        340        350        360
VRGMALFFYS HACNRICQSM GLTPFDLSPR EQDAVNQSTR LLQSAKTILR GTEEKCGSPR
       370        380        390        400        410        420
IRTLSSSRPP LLLRLSENSG DENMSDVTFD SLPSSPSSAT PHSQKLDHLH WPVFGDLDNM
       430        440        450        460        470        480
GPRDHDRMDN HRDSENSGDS GYPSEKRSDL DDPEPREHGH SNGNRRHESD EDSLGSSGRV
       490        500        510        520        530        540
CVETWNLLNP SRLHLPRPSA VALEVQRLNA LDLGRKIGKS VLGKVHLAMV RYHEGGRFCE
       550        560        570        580        590        600
KDEEWDRESA IFHLEHAADL GELEAIVGLG LMYSQLPHHI LADVSLKETE ENKTKGFDYL
       610        620        630        640        650        660
LKAAEAGDRH SMILVARAFD TGLNLSPDRC QDWSEALHWY NTALETTDCD EGGEYDGIQD
       670        680        690        700        710        720
EPQYALLARE AEMLLTGGFG LDKNPQRSGD LYTQAAEAAM EAMKGRLANQ YYEKAEEAWA

QMEE

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
O08796-2-unknown	MADEDL...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
O08796-2-unknown	MADEDL...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O08796-2-Acetylation	ADEDLI...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O08796-2-Acetylation	ADEDLI...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DEGYFI	38	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000119567
...HAQQWK	160	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000115486
...AQMEE	724	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)