TopFIND 4.0

O08873: MAP kinase-activating death domain protein

General Information

Protein names
- MAP kinase-activating death domain protein
- Rab3 GDP/GTP exchange factor
Gene names Madd {ECO:0000312|RGD:619922}
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID O08873

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MVQKKFCPRL LDYLVIVGAR HPSSDSVAQT PELLRRYPLE DHPEFPLPPD VVFFCQPEGC 
        70         80         90        100        110        120 
LSVRQRRMSL RDDTSFVFTL TDKDTGVTRY GICVNFYRSF QKRMPKEKAE GGAGPRGKEG 
       130        140        150        160        170        180 
AHAPCASEEA ATESSESGST LQPPSADSTP DVNQSPRGKR RAKAGNRSRN STLTSLCVLS 
       190        200        210        220        230        240 
HYPFFSTFRE CLYTLKRLVD CCSERLLGKK PGIPRGVQRD TMWRIFTGSL LVEEKSSALL 
       250        260        270        280        290        300 
HDLREIEAWI YRLLRSPVPV SGQKRVDIEV LPQEVQQALT FALPDPSRFT LVDFPLHLPL 
       310        320        330        340        350        360 
ELLGVDACLQ VLTCILLEHK VVLQSRDYNA LSMSVMAFVA MIYPLEYMFP VIPLLPTCMA 
       370        380        390        400        410        420 
SAEQLLLAPT PYIIGVPASF FLYKLDFKMP DDVWLVDLDS NRVIAPTNAE VLPILPEPES 
       430        440        450        460        470        480 
LELKKHLKQA LASMSLNTQP ILNLEKFHEG QETPLLLGRF SNDLQSTPST EFNPLIYGND 
       490        500        510        520        530        540 
VDSVDVATRV AMVRFFNSAN VLQGFQMHTR TLRLFPRPVV AFQAGSFLAS RPRQTPFAEK 
       550        560        570        580        590        600 
LARTQAVEYF GEWILNPSNY AFQRIHNNTF DPALIGDKPK WYAHQLQPIH YRVYDSNSQL 
       610        620        630        640        650        660 
AEALSVPPER DSESDPTDDS GSDSMDYDDS SSSYSSLGDF VSEMMKCDIN GDTPNVDPLT 
       670        680        690        700        710        720 
HAALGDASEV EIDELQPQKE GEEPGPDSEN SQENLPLRSS SSTTASSSPS TIVHGAHSEP 
       730        740        750        760        770        780 
ADSTEVGDKA ATGISKPLPP VPPSICKSTV DRRQTETGEG SVCQRTYDHP YFEPQYGSPA 
       790        800        810        820        830        840 
EEDDDEQGES YTPRFSQHAS GSRAQKLLRP NSLKLASDSD AESDSRASSP NSTVSNNSTE 
       850        860        870        880        890        900 
GFGGIMSFAS SLYRNHSTSF SLSNLTLPTK GAREKTTPFP SLKGNRRALV DQKSSVIKHS 
       910        920        930        940        950        960 
PTVKREPPSP QGRSSNSSEN QQFLKEVVHS VLDGQGVGWL NMKKVRRLLE SEQLRVFVLS 
       970        980        990       1000       1010       1020 
KLSRAVQSED DARQDVIQDV EISRKVYKGM LDLLKCTVLS LEQSYAHAGL GGMASIFGLL 
      1030       1040       1050       1060       1070       1080 
EIAQTHYYSK EPDKRKRSPT ENVNTPVGKD PGLAGRGDPK AMAQLRVPQL GPRAPSATGR 
      1090       1100       1110       1120       1130       1140 
GPKELDTRSL KEENFVASVG PEVIKPVFDL GETEEKKSQI SADSGVSLAS ASQRTDQDSV 
      1150       1160       1170       1180       1190       1200 
IGVSPAVMIR SSSQDSEVSN SSGETLGADS DLSSNAGDGP GGEGSAHLAS SRATLSDSEI 
      1210       1220       1230       1240       1250       1260 
ETNSATSTIF GKAHSLKPKE KPASSPVRSS EDVSQRVYLY EGLLGRDKGS MWDQLEDAAM 
      1270       1280       1290       1300       1310       1320 
ETFSISKERS TLWDQMQFWE DAFLDAVMLE REGMGMDQGP QEMIDRYLSL GEHDRKRLED 
      1330       1340       1350       1360       1370       1380 
DEDRLLATLL HNLISYMLLM KVNKNDIRKK VRRLMGKSHV GLVYSQQINE VLDQLTNLNG 
      1390       1400       1410       1420       1430       1440 
RDLSIRSSGS RHMKKQTFVV HAGTDTNGDI FFMEVCDDCV VLRSNIGTVY ERWWYEKLIN 
      1450       1460       1470       1480       1490       1500 
MTYCPKTKVL CLWRRNGSET QLNKFYTKKC RELYYCVKDS MERAAARQQS IKPGPELGGE 
      1510       1520       1530       1540       1550       1560 
FPVQDMKTGE GGLLQVTLEG INLKFMHNQV FIELNHIKKC NTVRGVFVLE EFVPEIKEVV 
      1570       1580       1590       1600    
SHKYKTPMAH EICYSVLCLF SYVAAVRSSE EDLRTPPRPV SS

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O08873-2-unknown VQKKFC... 2 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RPVSS 1602 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)