TopFIND 4.0

O08984: Delta(14)-sterol reductase

General Information

Protein names
- Delta(14)-sterol reductase
- Delta-14-SR
- 1.3.1.70 {ECO:0000250|UniProtKB:Q14739}
- 3-beta-hydroxysterol Delta (14)-reductase {ECO:0000250|UniProtKB:Q14739}
- C-14 sterol reductase
- C14SR
- Integral nuclear envelope inner membrane protein {ECO:0000250|UniProtKB:Q14739}
- Lamin-B receptor {ECO:0000250|UniProtKB:Q14739}
- NBP60 {ECO:0000303|PubMed:9192729}
- Sterol C14-reductase
Gene names Lbr
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID O08984

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MPGRKFADGE VVRGRWPGSS LYYEVEILSH DSTSQLYTVK YKDGTELELK ESDIKPLKSF 
        70         80         90        100        110        120 
KQRKSGSTSS SPSRRRSSRS RSRSRSRSPG RAPKGSRRSV SASYQADAKE KEMRREILQV 
       130        140        150        160        170        180 
KLTPLVLKPF ANSVSVYNGE PEHMEKSATP PKNKQERVIL STEDSYIATQ YSLRPRREEV 
       190        200        210        220        230        240 
KPKHRVRGTN LVTRGPVPLG TFQVTTPQRR DLEFGGVPGA LLIMLGLPAC VFLLLLQCAQ 
       250        260        270        280        290        300 
KDPGLLQFPP PLPALRELWE ARVCGVYLLW FFLQALFSLL PVGKVVEGTP LVDGRRLKYR 
       310        320        330        340        350        360 
LNGLYAFILT SAAVGTAVFW DIELYYLYTH FLQFALAAIV FSVVLSVYLY ARSLKVPRDE 
       370        380        390        400        410        420 
LSPASSGNAV YDFFIGRELN PRIGAFDLKF FCELRPGLIG WVVINLVMLL AEMKVQERSA 
       430        440        450        460        470        480 
PSLAMTLVNS FQLLYVVDAL WFEEALLTTM DIIHDGFGFM LAFGDLVWVP FTYSLQAFYL 
       490        500        510        520        530        540 
VNHPQDLSWP LTSVIIALKL CGYVIFRCAN SQKNAFRKNP TDPKLAHLKT IPTSTWKSLL 
       550        560        570        580        590        600 
VSGWWGFVRH PNYLGDLIMA LAWSLPCGFN HILPYFYVIY FTALLIHREA RDEHQCRRKY 
       610        620    
GLAWEKYCQR VPYRIFPYIY 

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O08984-1-unknown MPGRKF... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...FPYIY 620 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)