O14526: F-BAR domain only protein 1

General Information

Protein names	- F-BAR domain only protein 1
Gene names	FCHO1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O14526

4 N-termini

18 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of FCH domain only protein 1 - Isoform 3 of FCH domain only protein 1 - Isoform 2 of F-BAR domain only protein 1 - Isoform 3 of F-BAR domain only protein 1

Sequence View

        10         20         30         40         50         60
MSYFGEHFWG EKNHGFEVLY HSVKQGPIST KELADFIRER ATIEETYSKA MAKLSKLASN
        70         80         90        100        110        120
GTPMGTFAPL WEVFRVSSDK LALCHLELTR KLQDLIKDVL RYGEEQLKTH KKCKEEVVST
       130        140        150        160        170        180
LDAVQVLSGV SQLLPKSREN YLNRCMDQER LRRESTSQKE MDKAETKTKK AAESLRRSVE
       190        200        210        220        230        240
KYNSARADFE QKMLDSALRF QAMEETHLRH MKALLGSYAH SVEDTHVQIG QVHEEFKQNI
       250        260        270        280        290        300
ENVSVEMLLR KFAESKGTGR EKPGPLDFEA YSAAALQEAM KRLRGAKAFR LPGLSRRERE
       310        320        330        340        350        360
PEPPAAVDFL EPDSGTCPEV DEEGFTVRPD VTQNSTAEPS RFSSSDSDFD DEEPRKFYVH
       370        380        390        400        410        420
IKPAPARAPA CSPEAAAAQL RATAGSLILP PGPGGTMKRH SSRDAAGKPQ RPRSAPRTSS
       430        440        450        460        470        480
CAERLQSEEQ VSKNLFGPPL ESAFDHEDFT GSSSLGFTSS PSPFSSSSPE NVEDSGLDSP
       490        500        510        520        530        540
SHAAPGPSPD SWVPRPGTPQ SPPSCRAPPP EARGIRAPPL PDSPQPLASS PGPWGLEALA
       550        560        570        580        590        600
GGDLMPAPAD PTAREGLAAP PRRLRSRKVS CPLTRSNGDL SRSLSPSPLG SSAASTALER
       610        620        630        640        650        660
PSFLSQTGHG VSRGPSPVVL GSQDALPIAT AFTEYVHAYF RGHSPSCLAR VTGELTMTFP
       670        680        690        700        710        720
AGIVRVFSGT PPPPVLSFRL VHTTAIEHFQ PNADLLFSDP SQSDPETKDF WLNMAALTEA
       730        740        750        760        770        780
LQRQAEQNPT ASYYNVVLLR YQFSRPGPQS VPLQLSAHWQ CGATLTQVSV EYGYRPGATA
       790        800        810        820        830        840
VPTPLTNVQI LLPVGEPVTN VRLQPAATWN LEEKRLTWRL PDVSEAGGSG RLSASWEPLS
       850        860        870        880
GPSTPSPVAA QFTSEGTTLS GVDLELVGSG YRMSLVKRRF ATGMYLVSC         10         20         30         40         50         60
MSYFGEHFWG EKNHGFEVLY HSVKQGPIST KELADFIRER ATIEETYSKA MAKLSKLASN
        70         80         90        100        110        120
GTPMGTFAPL WEVFRVSSDK LALCHLELTR KLQDLIKDVL RYGEEQLKTH KKCKEEVVST
       130        140        150        160        170        180
LDAVQVLSGV SQLLPKSREN YLNRCMDQER LRRESTSQKE MDKAETKTKK AAESLRRSVE
       190        200        210        220        230        240
KYNSARADFE QKMLDSALRF QAMEETHLRH MKALLGSYAH SVEDTHVQIG QVHEEFKQNI
       250        260        270        280        290        300
ENVSVEMLLR KFAESKGTGR EKPGPLDFEA YSAAALQEAM KRLRGAKAFR LPGLSRRERE
       310        320        330        340        350        360
PEPPAAVDFL EPDSGTCPEV DEEGFTVRPD VTQNSTAEPS RFSSSDSDFD DEEPRKFYVH
       370        380        390        400        410        420
IKPAPARAPA CSPEAAAAQL RATAGSLILP PGPGGTMKRH SSRDAAGKPQ RPRSAPRTSS
       430        440        450        460        470        480
CAERLQSEEQ VSKNLFGPPL ESAFDHEDFT GSSSLGFTSS PSPFSSSSPE NVEDSGLDSP
       490        500        510        520        530        540
SHAAPGPSPD SWVPRPGTPQ SPPSCRAPPP EARGIRAPPL PDSPQPLASS PGPWGLEALA
       550        560        570        580        590        600
GGDLMPAPAD PTAREGLAAP PRRLRSRKVS CPLTRSNGDL SRSLSPSPLG SSAASTALER
       610        620        630        640        650        660
PSFLSQTGHG VSRGPSPVVL GSQDALPIAT AFTEYVHAYF RGHSPSCLAR VTGELTMTFP
       670        680        690        700        710        720
AGIVRVFSGT PPPPVLSFRL VHTTAIEHFQ PNADLLFSDP SQSDPETKDF WLNMAALTEA
       730        740        750        760        770        780
LQRQAEQNPT ASYYNVVLLR YQFSRPGPQS VPLQLSAHWQ CGATLTQVSV EYGYRPGATA
       790        800        810        820        830        840
VPTPLTNVQI LLPVGEPVTN VRLQPAATWN LEEKRLTWRL PDVSEAGGSG RLSASWEPLS
       850        860        870        880
GPSTPSPVAA QFTSEGTTLS GVDLELVGSG YRMSLVKRRF ATGMYLVSC         10         20         30         40         50         60
MSYFGEHFWG EKNHGFEVLY HSVKQGPIST KELADFIRER ATIEETYSKA MAKLSKLASN
        70         80         90        100        110        120
GTPMGTFAPL WEVFRVSSDK LALCHLELTR KLQDLIKDVL RYGEEQLKTH KKCKEEVVST
       130        140        150        160        170        180
LDAVQVLSGV SQLLPKSREN YLNRCMDQER LRRESTSQKE MDKAETKTKK AAESLRRSVE
       190        200        210        220        230        240
KYNSARADFE QKMLDSALRF QAMEETHLRH MKALLGSYAH SVEDTHVQIG QVHEEFKQNI
       250        260        270        280        290        300
ENVSVEMLLR KFAESKGTGR EKPGPLDFEA YSAAALQEAM KRLRGAKAFR LPGLSRRERE
       310        320        330        340        350        360
PEPPAAVDFL EPDSGTCPEV DEEGFTVRPD VTQNSTAEPS RFSSSDSDFD DEEPRKFYVH
       370        380        390        400        410        420
IKPAPARAPA CSPEAAAAQL RATAGSLILP PGPGGTMKRH SSRDAAGKPQ RPRSAPRTSS
       430        440        450        460        470        480
CAERLQSEEQ VSKNLFGPPL ESAFDHEDFT GSSSLGFTSS PSPFSSSSPE NVEDSGLDSP
       490        500        510        520        530        540
SHAAPGPSPD SWVPRPGTPQ SPPSCRAPPP EARGIRAPPL PDSPQPLASS PGPWGLEALA
       550        560        570        580        590        600
GGDLMPAPAD PTAREGLAAP PRRLRSRKVS CPLTRSNGDL SRSLSPSPLG SSAASTALER
       610        620        630        640        650        660
PSFLSQTGHG VSRGPSPVVL GSQDALPIAT AFTEYVHAYF RGHSPSCLAR VTGELTMTFP
       670        680        690        700        710        720
AGIVRVFSGT PPPPVLSFRL VHTTAIEHFQ PNADLLFSDP SQSDPETKDF WLNMAALTEA
       730        740        750        760        770        780
LQRQAEQNPT ASYYNVVLLR YQFSRPGPQS VPLQLSAHWQ CGATLTQVSV EYGYRPGATA
       790        800        810        820        830        840
VPTPLTNVQI LLPVGEPVTN VRLQPAATWN LEEKRLTWRL PDVSEAGGSG RLSASWEPLS
       850        860        870        880
GPSTPSPVAA QFTSEGTTLS GVDLELVGSG YRMSLVKRRF ATGMYLVSC         10         20         30         40         50         60
MSYFGEHFWG EKNHGFEVLY HSVKQGPIST KELADFIRER ATIEETYSKA MAKLSKLASN
        70         80         90        100        110        120
GTPMGTFAPL WEVFRVSSDK LALCHLELTR KLQDLIKDVL RYGEEQLKTH KKCKEEVVST
       130        140        150        160        170        180
LDAVQVLSGV SQLLPKSREN YLNRCMDQER LRRESTSQKE MDKAETKTKK AAESLRRSVE
       190        200        210        220        230        240
KYNSARADFE QKMLDSALRF QAMEETHLRH MKALLGSYAH SVEDTHVQIG QVHEEFKQNI
       250        260        270        280        290        300
ENVSVEMLLR KFAESKGTGR EKPGPLDFEA YSAAALQEAM KRLRGAKAFR LPGLSRRERE
       310        320        330        340        350        360
PEPPAAVDFL EPDSGTCPEV DEEGFTVRPD VTQNSTAEPS RFSSSDSDFD DEEPRKFYVH
       370        380        390        400        410        420
IKPAPARAPA CSPEAAAAQL RATAGSLILP PGPGGTMKRH SSRDAAGKPQ RPRSAPRTSS
       430        440        450        460        470        480
CAERLQSEEQ VSKNLFGPPL ESAFDHEDFT GSSSLGFTSS PSPFSSSSPE NVEDSGLDSP
       490        500        510        520        530        540
SHAAPGPSPD SWVPRPGTPQ SPPSCRAPPP EARGIRAPPL PDSPQPLASS PGPWGLEALA
       550        560        570        580        590        600
GGDLMPAPAD PTAREGLAAP PRRLRSRKVS CPLTRSNGDL SRSLSPSPLG SSAASTALER
       610        620        630        640        650        660
PSFLSQTGHG VSRGPSPVVL GSQDALPIAT AFTEYVHAYF RGHSPSCLAR VTGELTMTFP
       670        680        690        700        710        720
AGIVRVFSGT PPPPVLSFRL VHTTAIEHFQ PNADLLFSDP SQSDPETKDF WLNMAALTEA
       730        740        750        760        770        780
LQRQAEQNPT ASYYNVVLLR YQFSRPGPQS VPLQLSAHWQ CGATLTQVSV EYGYRPGATA
       790        800        810        820        830        840
VPTPLTNVQI LLPVGEPVTN VRLQPAATWN LEEKRLTWRL PDVSEAGGSG RLSASWEPLS
       850        860        870        880
GPSTPSPVAA QFTSEGTTLS GVDLELVGSG YRMSLVKRRF ATGMYLVSC

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 18 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O14526-1-unknown	MSYFGE...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O14526-1-unknown	MSYFGE...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt74983
O14526-51-unknown	MAKLSK...	51	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt74984
O14526-51-unknown	MAKLSK...	51	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000470495
O14526-51-unknown	MAKLSK...	51	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000472668
O14526-51-unknown	MAKLSK...	51	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt108730
O14526-326-unknown	TVRPDV...	326	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt175943
O14526-326-unknown	TVRPDV...	326	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt175944
O14526-326-	TVRPDV...	326		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...LYHSVK	23	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000469967
...LYHSVK	23	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt153698
...KQGPIS	28	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000469458
...KQGPIS	28	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt153748
...KELADF	35	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000470068
...KELADF	35	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt153775
...RERATI	42	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000469711
...RERATI	42	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt153824
...LTRKLQ	92	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000470511
...LTRKLQ	92	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt154284
...LTRKLQ	92	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt154285
...QDLIKD	97	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000472623
...QDLIKD	97	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt154334
...QDLIKD	97	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt154335
...KDVLRY	101	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000471563
...KDVLRY	101	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt154399
...KDVLRY	101	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt154400
...LKTHKK	111	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000469425
...LKTHKK	111	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt154488
...LKTHKK	111	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt154489
...LDAVQV	125	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000470730
...LDAVQV	125	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt154686
...LDAVQV	125	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt154687
...LRREST	155	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000469511
...LRREST	155	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt155031
...LRREST	155	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt155032
...AAESLR	175	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000469075
...AAESLR	175	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt155337
...AAESLR	175	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt155338
...EKYNSA	184	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000470495
...EKYNSA	184	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt155462
...EKYNSA	184	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt155463
...LDSALR	198	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000473173
...LDSALR	198	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt155593
...LDSALR	198	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt155594
...LLGSYA	218	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000473169
...LLGSYA	218	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt155795
...LLGSYA	218	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt155796
...SVEMLL	248	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000470578
...REKPGP	264	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000471935
...YLVSC	889	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...YLVSC	889	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt70602
...YLVSC	889		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...YLVSC	889		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)