TopFIND 4.0

O14544: Suppressor of cytokine signaling 6

General Information

Protein names
- Suppressor of cytokine signaling 6
- SOCS-6
- Cytokine-inducible SH2 protein 4
- CIS-4
- Suppressor of cytokine signaling 4
- SOCS-4
Gene names SOCS6
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID O14544

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MKKISLKTLR KSFNLNKSKE ETDFMVVQQP SLASDFGKDD SLFGSCYGKD MASCDINGED 
        70         80         90        100        110        120 
EKGGKNRSKS ESLMGTLKRR LSAKQKSKGK AGTPSGSSAD EDTFSSSSAP IVFKDVRAQR 
       130        140        150        160        170        180 
PIRSTSLRSH HYSPAPWPLR PTNSEETCIK MEVRVKALVH SSSPSPALNG VRKDFHDLQS 
       190        200        210        220        230        240 
ETTCQEQANS LKSSASHNGD LHLHLDEHVP VVIGLMPQDY IQYTVPLDEG MYPLEGSRSY 
       250        260        270        280        290        300 
CLDSSSPMEV SAVPPQVGGR AFPEDESQVD QDLVVAPEIF VDQSVNGLLI GTTGVMLQSP 
       310        320        330        340        350        360 
RAGHDDVPPL SPLLPPMQNN QIQRNFSGLT GTEAHVAESM RCHLNFDPNS APGVARVYDS 
       370        380        390        400        410        420 
VQSSGPMVVT SLTEELKKLA KQGWYWGPIT RWEAEGKLAN VPDGSFLVRD SSDDRYLLSL 
       430        440        450        460        470        480 
SFRSHGKTLH TRIEHSNGRF SFYEQPDVEG HTSIVDLIEH SIRDSENGAF CYSRSRLPGS 
       490        500        510        520        530    
ATYPVRLTNP VSRFMQVRSL QYLCRFVIRQ YTRIDLIQKL PLPNKMKDYL QEKHY

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O14544-1-unknown MKKISL... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)