O14717: tRNA (cytosine(38)-C(5))-methyltransferase

General Information

Protein names	- tRNA (cytosine(38)-C(5))-methyltransferase - 2.1.1.204 - DNA (cytosine-5)-methyltransferase-like protein 2 - Dnmt2 - DNA methyltransferase homolog HsaIIP - DNA MTase homolog HsaIIP - M.HsaIIP - PuMet
Gene names	TRDMT1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O14717

2 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform B of tRNA (cytosine(38)-C(5))-methyltransferase - Isoform C of tRNA (cytosine(38)-C(5))-methyltransferase - Isoform D of tRNA (cytosine(38)-C(5))-methyltransferase - Isoform E of tRNA (cytosine(38)-C(5))-methyltransferase - Isoform F of tRNA (cytosine(38)-C(5))-methyltransferase

Sequence View

        10         20         30         40         50         60
MEPLRVLELY SGVGGMHHAL RESCIPAQVV AAIDVNTVAN EVYKYNFPHT QLLAKTIEGI
        70         80         90        100        110        120
TLEEFDRLSF DMILMSPPCQ PFTRIGRQGD MTDSRTNSFL HILDILPRLQ KLPKYILLEN
       130        140        150        160        170        180
VKGFEVSSTR DLLIQTIENC GFQYQEFLLS PTSLGIPNSR LRYFLIAKLQ SEPLPFQAPG
       190        200        210        220        230        240
QVLMEFPKIE SVHPQKYAMD VENKIQEKNV EPNISFDGSI QCSGKDAILF KLETAEEIHR
       250        260        270        280        290        300
KNQQDSDLSV KMLKDFLEDD TDVNQYLLPP KSLLRYALLL DIVQPTCRRS VCFTKGYGSY
       310        320        330        340        350        360
IEGTGSVLQT AEDVQVENIY KSLTNLSQEE QITKLLILKL RYFTPKEIAN LLGFPPEFGF
       370        380        390
PEKITVKQRY RLLGNSLNVH VVAKLIKILY E         10         20         30         40         50         60
MEPLRVLELY SGVGGMHHAL RESCIPAQVV AAIDVNTVAN EVYKYNFPHT QLLAKTIEGI
        70         80         90        100        110        120
TLEEFDRLSF DMILMSPPCQ PFTRIGRQGD MTDSRTNSFL HILDILPRLQ KLPKYILLEN
       130        140        150        160        170        180
VKGFEVSSTR DLLIQTIENC GFQYQEFLLS PTSLGIPNSR LRYFLIAKLQ SEPLPFQAPG
       190        200        210        220        230        240
QVLMEFPKIE SVHPQKYAMD VENKIQEKNV EPNISFDGSI QCSGKDAILF KLETAEEIHR
       250        260        270        280        290        300
KNQQDSDLSV KMLKDFLEDD TDVNQYLLPP KSLLRYALLL DIVQPTCRRS VCFTKGYGSY
       310        320        330        340        350        360
IEGTGSVLQT AEDVQVENIY KSLTNLSQEE QITKLLILKL RYFTPKEIAN LLGFPPEFGF
       370        380        390
PEKITVKQRY RLLGNSLNVH VVAKLIKILY E         10         20         30         40         50         60
MEPLRVLELY SGVGGMHHAL RESCIPAQVV AAIDVNTVAN EVYKYNFPHT QLLAKTIEGI
        70         80         90        100        110        120
TLEEFDRLSF DMILMSPPCQ PFTRIGRQGD MTDSRTNSFL HILDILPRLQ KLPKYILLEN
       130        140        150        160        170        180
VKGFEVSSTR DLLIQTIENC GFQYQEFLLS PTSLGIPNSR LRYFLIAKLQ SEPLPFQAPG
       190        200        210        220        230        240
QVLMEFPKIE SVHPQKYAMD VENKIQEKNV EPNISFDGSI QCSGKDAILF KLETAEEIHR
       250        260        270        280        290        300
KNQQDSDLSV KMLKDFLEDD TDVNQYLLPP KSLLRYALLL DIVQPTCRRS VCFTKGYGSY
       310        320        330        340        350        360
IEGTGSVLQT AEDVQVENIY KSLTNLSQEE QITKLLILKL RYFTPKEIAN LLGFPPEFGF
       370        380        390
PEKITVKQRY RLLGNSLNVH VVAKLIKILY E         10         20         30         40         50         60
MEPLRVLELY SGVGGMHHAL RESCIPAQVV AAIDVNTVAN EVYKYNFPHT QLLAKTIEGI
        70         80         90        100        110        120
TLEEFDRLSF DMILMSPPCQ PFTRIGRQGD MTDSRTNSFL HILDILPRLQ KLPKYILLEN
       130        140        150        160        170        180
VKGFEVSSTR DLLIQTIENC GFQYQEFLLS PTSLGIPNSR LRYFLIAKLQ SEPLPFQAPG
       190        200        210        220        230        240
QVLMEFPKIE SVHPQKYAMD VENKIQEKNV EPNISFDGSI QCSGKDAILF KLETAEEIHR
       250        260        270        280        290        300
KNQQDSDLSV KMLKDFLEDD TDVNQYLLPP KSLLRYALLL DIVQPTCRRS VCFTKGYGSY
       310        320        330        340        350        360
IEGTGSVLQT AEDVQVENIY KSLTNLSQEE QITKLLILKL RYFTPKEIAN LLGFPPEFGF
       370        380        390
PEKITVKQRY RLLGNSLNVH VVAKLIKILY E         10         20         30         40         50         60
MEPLRVLELY SGVGGMHHAL RESCIPAQVV AAIDVNTVAN EVYKYNFPHT QLLAKTIEGI
        70         80         90        100        110        120
TLEEFDRLSF DMILMSPPCQ PFTRIGRQGD MTDSRTNSFL HILDILPRLQ KLPKYILLEN
       130        140        150        160        170        180
VKGFEVSSTR DLLIQTIENC GFQYQEFLLS PTSLGIPNSR LRYFLIAKLQ SEPLPFQAPG
       190        200        210        220        230        240
QVLMEFPKIE SVHPQKYAMD VENKIQEKNV EPNISFDGSI QCSGKDAILF KLETAEEIHR
       250        260        270        280        290        300
KNQQDSDLSV KMLKDFLEDD TDVNQYLLPP KSLLRYALLL DIVQPTCRRS VCFTKGYGSY
       310        320        330        340        350        360
IEGTGSVLQT AEDVQVENIY KSLTNLSQEE QITKLLILKL RYFTPKEIAN LLGFPPEFGF
       370        380        390
PEKITVKQRY RLLGNSLNVH VVAKLIKILY E

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
O14717-1-unknown	MEPLRV...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O14717-1-unknown	MEPLRV...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92960
O14717-1-unknown	MEPLRV...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92961
O14717-1-unknown	MEPLRV...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92962
O14717-1-unknown	MEPLRV...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92963
O14717-1-unknown	MEPLRV...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92964
O14717-19-unknown	ALRESC...	19	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000431476
O14717-19-unknown	ALRESC...	19	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt195175
O14717-19-unknown	ALRESC...	19	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt195176
O14717-19-unknown	ALRESC...	19	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt195177
O14717-19-unknown	ALRESC...	19	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt195178
O14717-19-unknown	ALRESC...	19	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt195179

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LPFQAP	178	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000431476
...LPFQAP	178	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155362
...LPFQAP	178	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155363
...SVCFTK	294	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000324263
...KILYE	391	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...KILYE	391	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt88579
...KILYE	391	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt88578

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)