TopFIND 4.0

O14730: Serine/threonine-protein kinase RIO3

General Information

Protein names
- Serine/threonine-protein kinase RIO3
- 2.7.11.1
- RIO kinase 3
- sudD homolog
Gene names RIOK3
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID O14730

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDLVGVASPE PGTAAAWGPS KCPWAIPQNT ISCSLADVMS EQLAKELQLE EEAAVFPEVA 
        70         80         90        100        110        120 
VAEGPFITGE NIDTSSDLML AQMLQMEYDR EYDAQLRREE KKFNGDSKVS ISFENYRKVH 
       130        140        150        160        170        180 
PYEDSDSSED EVDWQDTRDD PYRPAKPVPT PKKGFIGKGK DITTKHDEVV CGRKNTARME 
       190        200        210        220        230        240 
NFAPEFQVGD GIGMDLKLSN HVFNALKQHA YSEERRSARL HEKKEHSTAE KAVDPKTRLL 
       250        260        270        280        290        300 
MYKMVNSGML ETITGCISTG KESVVFHAYG GSMEDEKEDS KVIPTECAIK VFKTTLNEFK 
       310        320        330        340        350        360 
NRDKYIKDDF RFKDRFSKLN PRKIIRMWAE KEMHNLARMQ RAGIPCPTVV LLKKHILVMS 
       370        380        390        400        410        420 
FIGHDQVPAP KLKEVKLNSE EMKEAYYQTL HLMRQLYHEC TLVHADLSEY NMLWHAGKVW 
       430        440        450        460        470        480 
LIDVSQSVEP THPHGLEFLF RDCRNVSQFF QKGGVKEALS ERELFNAVSG LNITADNEAD 
       490        500        510    
FLAEIEALEK MNEDHVQKNG RKAASFLKDD GDPPLLYDE

Isoforms

- Isoform 2 of Serine/threonine-protein kinase RIO3

Sequence View

        10         20         30         40         50         60 
MDLVGVASPE PGTAAAWGPS KCPWAIPQNT ISCSLADVMS EQLAKELQLE EEAAVFPEVA 
        70         80         90        100        110        120 
VAEGPFITGE NIDTSSDLML AQMLQMEYDR EYDAQLRREE KKFNGDSKVS ISFENYRKVH 
       130        140        150        160        170        180 
PYEDSDSSED EVDWQDTRDD PYRPAKPVPT PKKGFIGKGK DITTKHDEVV CGRKNTARME 
       190        200        210        220        230        240 
NFAPEFQVGD GIGMDLKLSN HVFNALKQHA YSEERRSARL HEKKEHSTAE KAVDPKTRLL 
       250        260        270        280        290        300 
MYKMVNSGML ETITGCISTG KESVVFHAYG GSMEDEKEDS KVIPTECAIK VFKTTLNEFK 
       310        320        330        340        350        360 
NRDKYIKDDF RFKDRFSKLN PRKIIRMWAE KEMHNLARMQ RAGIPCPTVV LLKKHILVMS 
       370        380        390        400        410        420 
FIGHDQVPAP KLKEVKLNSE EMKEAYYQTL HLMRQLYHEC TLVHADLSEY NMLWHAGKVW 
       430        440        450        460        470        480 
LIDVSQSVEP THPHGLEFLF RDCRNVSQFF QKGGVKEALS ERELFNAVSG LNITADNEAD 
       490        500        510    
FLAEIEALEK MNEDHVQKNG RKAASFLKDD GDPPLLYDE



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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O14730-1-unknown MDLVGV... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    O14730-1-unknown MDLVGV... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt87780
    O14730-34- SLADVM... 34 Subtiligase Based Positive Selection Wells THP_untreated 23264352
    O14730-34-unknown SLADVM... 34 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt177478

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LLYDE 519 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...LLYDE 519 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt83398

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)