TopFIND 4.0

O14732: Inositol monophosphatase 2

General Information

Protein names
- Inositol monophosphatase 2
- IMP 2
- IMPase 2
- 3.1.3.25
- Inositol-1(or 4)-monophosphatase 2
- Myo-inositol monophosphatase A2
Gene names IMPA2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID O14732

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MKPSGEDQAA LAAGPWEECF QAAVQLALRA GQIIRKALTE EKRVSTKTSA ADLVTETDHL 
        70         80         90        100        110        120 
VEDLIISELR ERFPSHRFIA EEAAASGAKC VLTHSPTWII DPIDGTCNFV HRFPTVAVSI 
       130        140        150        160        170        180 
GFAVRQELEF GVIYHCTEER LYTGRRGRGA FCNGQRLRVS GETDLSKALV LTEIGPKRDP 
       190        200        210        220        230        240 
ATLKLFLSNM ERLLHAKAHG VRVIGSSTLA LCHLASGAAD AYYQFGLHCW DLAAATVIIR 
       250        260        270        280    
EAGGIVIDTS GGPLDLMACR VVAASTREMA MLIAQALQTI NYGRDDEK

Isoforms

- Isoform 2 of Inositol monophosphatase 2

Sequence View

        10         20         30         40         50         60 
MKPSGEDQAA LAAGPWEECF QAAVQLALRA GQIIRKALTE EKRVSTKTSA ADLVTETDHL 
        70         80         90        100        110        120 
VEDLIISELR ERFPSHRFIA EEAAASGAKC VLTHSPTWII DPIDGTCNFV HRFPTVAVSI 
       130        140        150        160        170        180 
GFAVRQELEF GVIYHCTEER LYTGRRGRGA FCNGQRLRVS GETDLSKALV LTEIGPKRDP 
       190        200        210        220        230        240 
ATLKLFLSNM ERLLHAKAHG VRVIGSSTLA LCHLASGAAD AYYQFGLHCW DLAAATVIIR 
       250        260        270        280    
EAGGIVIDTS GGPLDLMACR VVAASTREMA MLIAQALQTI NYGRDDEK



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Physiological Relevance:


Evidence Codes:


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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O14732-1-unknown MKPSGE... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RDDEK 288 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...RDDEK 288 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt73476

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)