TopFIND 4.0

O14772: Fucose-1-phosphate guanylyltransferase

General Information

Protein names
- Fucose-1-phosphate guanylyltransferase
- 2.7.7.30
- GDP-L-fucose diphosphorylase
- GDP-L-fucose pyrophosphorylase
Gene names FPGT
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID O14772

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MRAVRRGLRE GGAMAAARDP PEVSLREATQ RKLRRFSELR GKLVARGEFW DIVAITAADE 
        70         80         90        100        110        120 
KQELAYNQQL SEKLKRKELP LGVQYHVFVD PAGAKIGNGG STLCALQCLE KLYGDKWNSF 
       130        140        150        160        170        180 
TILLIHSGGY SQRLPNASAL GKIFTALPLG NPIYQMLELK LAMYIDFPLN MNPGILVTCA 
       190        200        210        220        230        240 
DDIELYSIGE FEFIRFDKPG FTALAHPSSL TIGTTHGVFV LDPFDDLKHR DLEYRSCHRF 
       250        260        270        280        290        300 
LHKPSIEKMY QFNAVCRPGN FCQQDFAGGD IADLKLDSDY VYTDSLFYMD HKSAKMLLAF 
       310        320        330        340        350        360 
YEKIGTLSCE IDAYGDFLQA LGPGATVEYT RNTSNVIKEE SELVEMRQRI FHLLKGTSLN 
       370        380        390        400        410        420 
VVVLNNSKFY HIGTTEEYLF YFTSDNSLKS ELGLQSITFS IFPDIPECSG KTSCIIQSIL 
       430        440        450        460        470        480 
DSRCSVAPGS VVEYSRLGPD VSVGENCIIS GSYILTKAAL PAHSFVCSLS LKMNRCLKYA 
       490        500        510        520        530        540 
TMAFGVQDNL KKSVKTLSDI KLLQFFGVCF LSCLDVWNLK VTEELFSGNK TCLSLWTARI 
       550        560        570        580        590        600 
FPVCSSLSDS VITSLKMLNA VKNKSAFSLN SYKLLSIEEM LIYKDVEDMI TYREQIFLEI 
   
SLKSSLM

Isoforms

- Isoform 5 of Fucose-1-phosphate guanylyltransferase - Isoform 6 of Fucose-1-phosphate guanylyltransferase

Sequence View

        10         20         30         40         50         60 
MRAVRRGLRE GGAMAAARDP PEVSLREATQ RKLRRFSELR GKLVARGEFW DIVAITAADE 
        70         80         90        100        110        120 
KQELAYNQQL SEKLKRKELP LGVQYHVFVD PAGAKIGNGG STLCALQCLE KLYGDKWNSF 
       130        140        150        160        170        180 
TILLIHSGGY SQRLPNASAL GKIFTALPLG NPIYQMLELK LAMYIDFPLN MNPGILVTCA 
       190        200        210        220        230        240 
DDIELYSIGE FEFIRFDKPG FTALAHPSSL TIGTTHGVFV LDPFDDLKHR DLEYRSCHRF 
       250        260        270        280        290        300 
LHKPSIEKMY QFNAVCRPGN FCQQDFAGGD IADLKLDSDY VYTDSLFYMD HKSAKMLLAF 
       310        320        330        340        350        360 
YEKIGTLSCE IDAYGDFLQA LGPGATVEYT RNTSNVIKEE SELVEMRQRI FHLLKGTSLN 
       370        380        390        400        410        420 
VVVLNNSKFY HIGTTEEYLF YFTSDNSLKS ELGLQSITFS IFPDIPECSG KTSCIIQSIL 
       430        440        450        460        470        480 
DSRCSVAPGS VVEYSRLGPD VSVGENCIIS GSYILTKAAL PAHSFVCSLS LKMNRCLKYA 
       490        500        510        520        530        540 
TMAFGVQDNL KKSVKTLSDI KLLQFFGVCF LSCLDVWNLK VTEELFSGNK TCLSLWTARI 
       550        560        570        580        590        600 
FPVCSSLSDS VITSLKMLNA VKNKSAFSLN SYKLLSIEEM LIYKDVEDMI TYREQIFLEI 
   
SLKSSLM         10         20         30         40         50         60 
MRAVRRGLRE GGAMAAARDP PEVSLREATQ RKLRRFSELR GKLVARGEFW DIVAITAADE 
        70         80         90        100        110        120 
KQELAYNQQL SEKLKRKELP LGVQYHVFVD PAGAKIGNGG STLCALQCLE KLYGDKWNSF 
       130        140        150        160        170        180 
TILLIHSGGY SQRLPNASAL GKIFTALPLG NPIYQMLELK LAMYIDFPLN MNPGILVTCA 
       190        200        210        220        230        240 
DDIELYSIGE FEFIRFDKPG FTALAHPSSL TIGTTHGVFV LDPFDDLKHR DLEYRSCHRF 
       250        260        270        280        290        300 
LHKPSIEKMY QFNAVCRPGN FCQQDFAGGD IADLKLDSDY VYTDSLFYMD HKSAKMLLAF 
       310        320        330        340        350        360 
YEKIGTLSCE IDAYGDFLQA LGPGATVEYT RNTSNVIKEE SELVEMRQRI FHLLKGTSLN 
       370        380        390        400        410        420 
VVVLNNSKFY HIGTTEEYLF YFTSDNSLKS ELGLQSITFS IFPDIPECSG KTSCIIQSIL 
       430        440        450        460        470        480 
DSRCSVAPGS VVEYSRLGPD VSVGENCIIS GSYILTKAAL PAHSFVCSLS LKMNRCLKYA 
       490        500        510        520        530        540 
TMAFGVQDNL KKSVKTLSDI KLLQFFGVCF LSCLDVWNLK VTEELFSGNK TCLSLWTARI 
       550        560        570        580        590        600 
FPVCSSLSDS VITSLKMLNA VKNKSAFSLN SYKLLSIEEM LIYKDVEDMI TYREQIFLEI 
   
SLKSSLM



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Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O14772-1-unknown MRAVRR... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    O14772-1-unknown MRAVRR... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt75428
    O14772-1-unknown MRAVRR... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt75429

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...ITYREQ 594 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...ITYREQ 594 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt71046

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)