TopFIND 4.0

O14926: Fascin-2

General Information

Protein names
- Fascin-2
- Retinal fascin
Gene names FSCN2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID O14926

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MPTNGLHQVL KIQFGLVNDT DRYLTAESFG FKVNASAPSL KRKQTWVLEP DPGQGTAVLL 
        70         80         90        100        110        120 
RSSHLGRYLS AEEDGRVACE AEQPGRDCRF LVLPQPDGRW VLRSEPHGRF FGGTEDQLSC 
       130        140        150        160        170        180 
FATAVSPAEL WTVHLAIHPQ AHLLSVSRRR YVHLCPREDE MAADGDKPWG VDALLTLIFR 
       190        200        210        220        230        240 
SRRYCLKSCD SRYLRSDGRL VWEPEPRACY TLEFKAGKLA FKDCDGHYLA PVGPAGTLKA 
       250        260        270        280        290        300 
GRNTRPGKDE LFDLEESHPQ VVLVAANHRY VSVRQGVNVS ANQDDELDHE TFLMQIDQET 
       310        320        330        340        350        360 
KKCTFYSSTG GYWTLVTHGG IHATATQVSA NTMFEMEWRG RRVALKASNG RYVCMKKNGQ 
       370        380        390        400        410        420 
LAAISDFVGK DEEFTLKLIN RPILVLRGLD GFVCHHRGSN QLDTNRSVYD VFHLSFSDGA 
       430        440        450        460        470        480 
YRIRGRDGGF WYTGSHGSVC SDGERAEDFV FEFRERGRLA IRARSGKYLR GGASGLLRAD 
       490    
ADAPAGTALW EY

Isoforms

- Isoform 2 of Fascin-2

Sequence View

        10         20         30         40         50         60 
MPTNGLHQVL KIQFGLVNDT DRYLTAESFG FKVNASAPSL KRKQTWVLEP DPGQGTAVLL 
        70         80         90        100        110        120 
RSSHLGRYLS AEEDGRVACE AEQPGRDCRF LVLPQPDGRW VLRSEPHGRF FGGTEDQLSC 
       130        140        150        160        170        180 
FATAVSPAEL WTVHLAIHPQ AHLLSVSRRR YVHLCPREDE MAADGDKPWG VDALLTLIFR 
       190        200        210        220        230        240 
SRRYCLKSCD SRYLRSDGRL VWEPEPRACY TLEFKAGKLA FKDCDGHYLA PVGPAGTLKA 
       250        260        270        280        290        300 
GRNTRPGKDE LFDLEESHPQ VVLVAANHRY VSVRQGVNVS ANQDDELDHE TFLMQIDQET 
       310        320        330        340        350        360 
KKCTFYSSTG GYWTLVTHGG IHATATQVSA NTMFEMEWRG RRVALKASNG RYVCMKKNGQ 
       370        380        390        400        410        420 
LAAISDFVGK DEEFTLKLIN RPILVLRGLD GFVCHHRGSN QLDTNRSVYD VFHLSFSDGA 
       430        440        450        460        470        480 
YRIRGRDGGF WYTGSHGSVC SDGERAEDFV FEFRERGRLA IRARSGKYLR GGASGLLRAD 
       490    
ADAPAGTALW EY



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O14926-1-unknown MPTNGL... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    O14926-1-unknown MPTNGL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt75498

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...ALWEY 492 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...ALWEY 492 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt71116

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)