O14939: Phospholipase D2

General Information

Protein names	- Phospholipase D2 - PLD 2 - hPLD2 - 3.1.4.4 - Choline phosphatase 2 - PLD1C - Phosphatidylcholine-hydrolyzing phospholipase D2
Gene names	PLD2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O14939

2 N-termini

4 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MTATPESLFP TGDELDSSQL QMESDEVDTL KEGEDPADRM HPFLAIYELQ SLKVHPLVFA
        70         80         90        100        110        120
PGVPVTAQVV GTERYTSGSK VGTCTLYSVR LTHGDFSWTT KKKYRHFQEL HRDLLRHKVL
       130        140        150        160        170        180
MSLLPLARFA VAYSPARDAG NREMPSLPRA GPEGSTRHAA SKQKYLENYL NRLLTMSFYR
       190        200        210        220        230        240
NYHAMTEFLE VSQLSFIPDL GRKGLEGMIR KRSGGHRVPG LTCCGRDQVC YRWSKRWLVV
       250        260        270        280        290        300
KDSFLLYMCL ETGAISFVQL FDPGFEVQVG KRSTEARHGV RIDTSHRSLI LKCSSYRQAR
       310        320        330        340        350        360
WWAQEITELA QGPGRDFLQL HRHDSYAPPR PGTLARWFVN GAGYFAAVAD AILRAQEEIF
       370        380        390        400        410        420
ITDWWLSPEV YLKRPAHSDD WRLDIMLKRK AEEGVRVSIL LFKEVELALG INSGYSKRAL
       430        440        450        460        470        480
MLLHPNIKVM RHPDQVTLWA HHEKLLVVDQ VVAFLGGLDL AYGRWDDLHY RLTDLGDSSE
       490        500        510        520        530        540
SAASQPPTPR PDSPATPDLS HNQFFWLGKD YSNLITKDWV QLDRPFEDFI DRETTPRMPW
       550        560        570        580        590        600
RDVGVVVHGL PARDLARHFI QRWNFTKTTK AKYKTPTYPY LLPKSTSTAN QLPFTLPGGQ
       610        620        630        640        650        660
CTTVQVLRSV DRWSAGTLEN SILNAYLHTI RESQHFLYIE NQFFISCSDG RTVLNKVGDE
       670        680        690        700        710        720
IVDRILKAHK QGWCYRVYVL LPLLPGFEGD ISTGGGNSIQ AILHFTYRTL CRGEYSILHR
       730        740        750        760        770        780
LKAAMGTAWR DYISICGLRT HGELGGHPVS ELIYIHSKVL IADDRTVIIG SANINDRSLL
       790        800        810        820        830        840
GKRDSELAVL IEDTETEPSL MNGAEYQAGR FALSLRKHCF GVILGANTRP DLDLRDPICD
       850        860        870        880        890        900
DFFQLWQDMA ESNANIYEQI FRCLPSNATR SLRTLREYVA VEPLATVSPP LARSELTQVQ
       910        920        930
GHLVHFPLKF LEDESLLPPL GSKEGMIPLE VWT

Isoforms

- Isoform PLD2C of Phospholipase D2 - Isoform PLD2B of Phospholipase D2

Sequence View

        10         20         30         40         50         60
MTATPESLFP TGDELDSSQL QMESDEVDTL KEGEDPADRM HPFLAIYELQ SLKVHPLVFA
        70         80         90        100        110        120
PGVPVTAQVV GTERYTSGSK VGTCTLYSVR LTHGDFSWTT KKKYRHFQEL HRDLLRHKVL
       130        140        150        160        170        180
MSLLPLARFA VAYSPARDAG NREMPSLPRA GPEGSTRHAA SKQKYLENYL NRLLTMSFYR
       190        200        210        220        230        240
NYHAMTEFLE VSQLSFIPDL GRKGLEGMIR KRSGGHRVPG LTCCGRDQVC YRWSKRWLVV
       250        260        270        280        290        300
KDSFLLYMCL ETGAISFVQL FDPGFEVQVG KRSTEARHGV RIDTSHRSLI LKCSSYRQAR
       310        320        330        340        350        360
WWAQEITELA QGPGRDFLQL HRHDSYAPPR PGTLARWFVN GAGYFAAVAD AILRAQEEIF
       370        380        390        400        410        420
ITDWWLSPEV YLKRPAHSDD WRLDIMLKRK AEEGVRVSIL LFKEVELALG INSGYSKRAL
       430        440        450        460        470        480
MLLHPNIKVM RHPDQVTLWA HHEKLLVVDQ VVAFLGGLDL AYGRWDDLHY RLTDLGDSSE
       490        500        510        520        530        540
SAASQPPTPR PDSPATPDLS HNQFFWLGKD YSNLITKDWV QLDRPFEDFI DRETTPRMPW
       550        560        570        580        590        600
RDVGVVVHGL PARDLARHFI QRWNFTKTTK AKYKTPTYPY LLPKSTSTAN QLPFTLPGGQ
       610        620        630        640        650        660
CTTVQVLRSV DRWSAGTLEN SILNAYLHTI RESQHFLYIE NQFFISCSDG RTVLNKVGDE
       670        680        690        700        710        720
IVDRILKAHK QGWCYRVYVL LPLLPGFEGD ISTGGGNSIQ AILHFTYRTL CRGEYSILHR
       730        740        750        760        770        780
LKAAMGTAWR DYISICGLRT HGELGGHPVS ELIYIHSKVL IADDRTVIIG SANINDRSLL
       790        800        810        820        830        840
GKRDSELAVL IEDTETEPSL MNGAEYQAGR FALSLRKHCF GVILGANTRP DLDLRDPICD
       850        860        870        880        890        900
DFFQLWQDMA ESNANIYEQI FRCLPSNATR SLRTLREYVA VEPLATVSPP LARSELTQVQ
       910        920        930
GHLVHFPLKF LEDESLLPPL GSKEGMIPLE VWT         10         20         30         40         50         60
MTATPESLFP TGDELDSSQL QMESDEVDTL KEGEDPADRM HPFLAIYELQ SLKVHPLVFA
        70         80         90        100        110        120
PGVPVTAQVV GTERYTSGSK VGTCTLYSVR LTHGDFSWTT KKKYRHFQEL HRDLLRHKVL
       130        140        150        160        170        180
MSLLPLARFA VAYSPARDAG NREMPSLPRA GPEGSTRHAA SKQKYLENYL NRLLTMSFYR
       190        200        210        220        230        240
NYHAMTEFLE VSQLSFIPDL GRKGLEGMIR KRSGGHRVPG LTCCGRDQVC YRWSKRWLVV
       250        260        270        280        290        300
KDSFLLYMCL ETGAISFVQL FDPGFEVQVG KRSTEARHGV RIDTSHRSLI LKCSSYRQAR
       310        320        330        340        350        360
WWAQEITELA QGPGRDFLQL HRHDSYAPPR PGTLARWFVN GAGYFAAVAD AILRAQEEIF
       370        380        390        400        410        420
ITDWWLSPEV YLKRPAHSDD WRLDIMLKRK AEEGVRVSIL LFKEVELALG INSGYSKRAL
       430        440        450        460        470        480
MLLHPNIKVM RHPDQVTLWA HHEKLLVVDQ VVAFLGGLDL AYGRWDDLHY RLTDLGDSSE
       490        500        510        520        530        540
SAASQPPTPR PDSPATPDLS HNQFFWLGKD YSNLITKDWV QLDRPFEDFI DRETTPRMPW
       550        560        570        580        590        600
RDVGVVVHGL PARDLARHFI QRWNFTKTTK AKYKTPTYPY LLPKSTSTAN QLPFTLPGGQ
       610        620        630        640        650        660
CTTVQVLRSV DRWSAGTLEN SILNAYLHTI RESQHFLYIE NQFFISCSDG RTVLNKVGDE
       670        680        690        700        710        720
IVDRILKAHK QGWCYRVYVL LPLLPGFEGD ISTGGGNSIQ AILHFTYRTL CRGEYSILHR
       730        740        750        760        770        780
LKAAMGTAWR DYISICGLRT HGELGGHPVS ELIYIHSKVL IADDRTVIIG SANINDRSLL
       790        800        810        820        830        840
GKRDSELAVL IEDTETEPSL MNGAEYQAGR FALSLRKHCF GVILGANTRP DLDLRDPICD
       850        860        870        880        890        900
DFFQLWQDMA ESNANIYEQI FRCLPSNATR SLRTLREYVA VEPLATVSPP LARSELTQVQ
       910        920        930
GHLVHFPLKF LEDESLLPPL GSKEGMIPLE VWT

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
O14939-1-unknown	MTATPE...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O14939-1-unknown	MTATPE...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt85524
O14939-1-unknown	MTATPE...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt85525
O14939-567-unknown	KTTKAK...	567	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000460250
O14939-567-unknown	KTTKAK...	567	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt199895

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...NYLNRL	172	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000458795
...NYLNRL	172	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155282
...NYLNRL	172	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155283
...GTLARW	336	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt81142
...GTLARW	336	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92443
...TETEPS	798	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000460250
...LEVWT	933	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...LEVWT	933	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt81143

TopFIND

O14939: Phospholipase D2

General Information

2

N-termini

4

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

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Evidence Codes:

Methodology:

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Protein Neighborhood

Domains & Features

2 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates