O14986: Phosphatidylinositol 4-phosphate 5-kinase type-1 beta

General Information

Protein names	- Phosphatidylinositol 4-phosphate 5-kinase type-1 beta - PIP5K1-beta - PtdIns(4)P-5-kinase 1 beta - 2.7.1.68 - Phosphatidylinositol 4-phosphate 5-kinase type I beta - PIP5KIbeta - Protein STM-7 - Type I phosphatidylinositol 4-phosphate 5-kinase beta
Gene names	PIP5K1B
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O14986

1 N-termini

5 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Phosphatidylinositol 4-phosphate 5-kinase type-1 beta - Isoform 3 of Phosphatidylinositol 4-phosphate 5-kinase type-1 beta

Sequence View

        10         20         30         40         50         60
MSSAAENGEA APGKQNEEKT YKKTASSAIK GAIQLGIGYT VGNLTSKPER DVLMQDFYVV
        70         80         90        100        110        120
ESVFLPSEGS NLTPAHHYPD FRFKTYAPLA FRYFRELFGI KPDDYLYSIC SEPLIELSNP
       130        140        150        160        170        180
GASGSLFFVT SDDEFIIKTV QHKEAEFLQK LLPGYYMNLN QNPRTLLPKF YGLYCMQSGG
       190        200        210        220        230        240
INIRIVVMNN VLPRSMRMHF TYDLKGSTYK RRASRKEREK SNPTFKDLDF LQDMHEGLYF
       250        260        270        280        290        300
DTETYNALMK TLQRDCRVLE SFKIMDYSLL LGIHFLDHSL KEKEEETPQN VPDAKRTGMQ
       310        320        330        340        350        360
KVLYSTAMES IQGPGKSGDG IITENPDTMG GIPAKSHRGE KLLLFMGIID ILQSYRLMKK
       370        380        390        400        410        420
LEHSWKALVY DGDTVSVHRP SFYADRFLKF MNSRVFKKIQ ALKASPSKKR CNSIAALKAT
       430        440        450        460        470        480
SQEIVSSISQ EWKDEKRDLL TEGQSFSSLD EEALGSRHRP DLVPSTPSLF EAASLATTIS
       490        500        510        520        530        540
SSSLYVNEHY PHDRPTLYSN SKGLPSSSTF TLEEGTIYLT AEPNTLEVQD DNASVLDVYL

        10         20         30         40         50         60
MSSAAENGEA APGKQNEEKT YKKTASSAIK GAIQLGIGYT VGNLTSKPER DVLMQDFYVV
        70         80         90        100        110        120
ESVFLPSEGS NLTPAHHYPD FRFKTYAPLA FRYFRELFGI KPDDYLYSIC SEPLIELSNP
       130        140        150        160        170        180
GASGSLFFVT SDDEFIIKTV QHKEAEFLQK LLPGYYMNLN QNPRTLLPKF YGLYCMQSGG
       190        200        210        220        230        240
INIRIVVMNN VLPRSMRMHF TYDLKGSTYK RRASRKEREK SNPTFKDLDF LQDMHEGLYF
       250        260        270        280        290        300
DTETYNALMK TLQRDCRVLE SFKIMDYSLL LGIHFLDHSL KEKEEETPQN VPDAKRTGMQ
       310        320        330        340        350        360
KVLYSTAMES IQGPGKSGDG IITENPDTMG GIPAKSHRGE KLLLFMGIID ILQSYRLMKK
       370        380        390        400        410        420
LEHSWKALVY DGDTVSVHRP SFYADRFLKF MNSRVFKKIQ ALKASPSKKR CNSIAALKAT
       430        440        450        460        470        480
SQEIVSSISQ EWKDEKRDLL TEGQSFSSLD EEALGSRHRP DLVPSTPSLF EAASLATTIS
       490        500        510        520        530        540
SSSLYVNEHY PHDRPTLYSN SKGLPSSSTF TLEEGTIYLT AEPNTLEVQD DNASVLDVYL

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

1 N-termini - 5 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
O14986-1-unknown	MSSAAE...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O14986-1-unknown	MSSAAE...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt85138
O14986-1-unknown	MSSAAE...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt85139

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GIKPDD	103	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000366498
...GIKPDD	103	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154420
...GIKPDD	103	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154421
...PGYYMN	157	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000411477
...PGYYMN	157	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155054
...PGYYMN	157	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155055
...NLNQNP	162	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000398587
...NLNQNP	162	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155127
...NLNQNP	162	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155128
...YSNSKG	502	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt80757
...YSNSKG	502	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000438082
...LDVYL	540	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)