O15031: Plexin-B2

General Information

Protein names	- Plexin-B2 - MM1
Gene names	PLXNB2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O15031

3 N-termini

6 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MALQLWALTL LGLLGAGASL RPRKLDFFRS EKELNHLAVD EASGVVYLGA VNALYQLDAK
        70         80         90        100        110        120
LQLEQQVATG PALDNKKCTP PIEASQCHEA EMTDNVNQLL LLDPPRKRLV ECGSLFKGIC
       130        140        150        160        170        180
ALRALSNISL RLFYEDGSGE KSFVASNDEG VATVGLVSST GPGGDRVLFV GKGNGPHDNG
       190        200        210        220        230        240
IIVSTRLLDR TDSREAFEAY TDHATYKAGY LSTNTQQFVA AFEDGPYVFF VFNQQDKHPA
       250        260        270        280        290        300
RNRTLLARMC REDPNYYSYL EMDLQCRDPD IHAAAFGTCL AASVAAPGSG RVLYAVFSRD
       310        320        330        340        350        360
SRSSGGPGAG LCLFPLDKVH AKMEANRNAC YTGTREARDI FYKPFHGDIQ CGGHAPGSSK
       370        380        390        400        410        420
SFPCGSEHLP YPLGSRDGLR GTAVLQRGGL NLTAVTVAAE NNHTVAFLGT SDGRILKVYL
       430        440        450        460        470        480
TPDGTSSEYD SILVEINKRV KRDLVLSGDL GSLYAMTQDK VFRLPVQECL SYPTCTQCRD
       490        500        510        520        530        540
SQDPYCGWCV VEGRCTRKAE CPRAEEASHW LWSRSKSCVA VTSAQPQNMS RRAQGEVQLT
       550        560        570        580        590        600
VSPLPALSEE DELLCLFGES PPHPARVEGE AVICNSPSSI PVTPPGQDHV AVTIQLLLRR
       610        620        630        640        650        660
GNIFLTSYQY PFYDCRQAMS LEENLPCISC VSNRWTCQWD LRYHECREAS PNPEDGIVRA
       670        680        690        700        710        720
HMEDSCPQFL GPSPLVIPMN HETDVNFQGK NLDTVKGSSL HVGSDLLKFM EPVTMQESGT
       730        740        750        760        770        780
FAFRTPKLSH DANETLPLHL YVKSYGKNID SKLHVTLYNC SFGRSDCSLC RAANPDYRCA
       790        800        810        820        830        840
WCGGQSRCVY EALCNTTSEC PPPVITRIQP ETGPLGGGIR ITILGSNLGV QAGDIQRISV
       850        860        870        880        890        900
AGRNCSFQPE RYSVSTRIVC VIEAAETPFT GGVEVDVFGK LGRSPPNVQF TFQQPKPLSV
       910        920        930        940        950        960
EPQQGPQAGG TTLTIHGTHL DTGSQEDVRV TLNGVPCKVT KFGAQLQCVT GPQATRGQML
       970        980        990       1000       1010       1020
LEVSYGGSPV PNPGIFFTYR ENPVLRAFEP LRSFASGGRS INVTGQGFSL IQRFAMVVIA
      1030       1040       1050       1060       1070       1080
EPLQSWQPPR EAESLQPMTV VGTDYVFHND TKVVFLSPAV PEEPEAYNLT VLIEMDGHRA
      1090       1100       1110       1120       1130       1140
LLRTEAGAFE YVPDPTFENF TGGVKKQVNK LIHARGTNLN KAMTLQEAEA FVGAERCTMK
      1150       1160       1170       1180       1190       1200
TLTETDLYCE PPEVQPPPKR RQKRDTTHNL PEFIVKFGSR EWVLGRVEYD TRVSDVPLSL
      1210       1220       1230       1240       1250       1260
ILPLVIVPMV VVIAVSVYCY WRKSQQAERE YEKIKSQLEG LEESVRDRCK KEFTDLMIEM
      1270       1280       1290       1300       1310       1320
EDQTNDVHEA GIPVLDYKTY TDRVFFLPSK DGDKDVMITG KLDIPEPRRP VVEQALYQFS
      1330       1340       1350       1360       1370       1380
NLLNSKSFLI NFIHTLENQR EFSARAKVYF ASLLTVALHG KLEYYTDIMH TLFLELLEQY
      1390       1400       1410       1420       1430       1440
VVAKNPKLML RRSETVVERM LSNWMSICLY QYLKDSAGEP LYKLFKAIKH QVEKGPVDAV
      1450       1460       1470       1480       1490       1500
QKKAKYTLND TGLLGDDVEY APLTVSVIVQ DEGVDAIPVK VLNCDTISQV KEKIIDQVYR
      1510       1520       1530       1540       1550       1560
GQPCSCWPRP DSVVLEWRPG STAQILSDLD LTSQREGRWK RVNTLMHYNV RDGATLILSK
      1570       1580       1590       1600       1610       1620
VGVSQQPEDS QQDLPGERHA LLEEENRVWH LVRPTDEVDE GKSKRGSVKE KERTKAITEI
      1630       1640       1650       1660       1670       1680
YLTRLLSVKG TLQQFVDNFF QSVLAPGHAV PPAVKYFFDF LDEQAEKHNI QDEDTIHIWK
      1690       1700       1710       1720       1730       1740
TNSLPLRFWV NILKNPHFIF DVHVHEVVDA SLSVIAQTFM DACTRTEHKL SRDSPSNKLL
      1750       1760       1770       1780       1790       1800
YAKEISTYKK MVEDYYKGIR QMVQVSDQDM NTHLAEISRA HTDSLNTLVA LHQLYQYTQK
      1810       1820       1830
YYDEIINALE EDPAAQKMQL AFRLQQIAAA LENKVTDL

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 6 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name	Publications (PMID)
O15031-20-unknown	LRPRKL...	20	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O15031-342-unknown	YKPFHG...	342	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000400679
O15031-1016-unknown	MVVIAE...	1016		unknown		Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...VSSTGP	161	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000387470
...PTCTQC	477	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000392620
...LHLYVK	742	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000415757
...THNLPE	1171	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000406048
...IWKTNS	1682	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000400679
...KVTDL	1838	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)