O15127: Secretory carrier-associated membrane protein 2

General Information

Protein names	- Secretory carrier-associated membrane protein 2 - Secretory carrier membrane protein 2
Gene names	SCAMP2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O15127

5 N-termini

5 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSAFDTNPFA DPVDVNPFQD PSVTQLTNAP QGGLAEFNPF SETNAATTVP VTQLPGSSQP
        70         80         90        100        110        120
AVLQPSVEPT QPTPQAVVSA AQAGLLRQQE ELDRKAAELE RKERELQNTV ANLHVRQNNW
       130        140        150        160        170        180
PPLPSWCPVK PCFYQDFSTE IPADYQRICK MLYYLWMLHS VTLFLNLLAC LAWFSGNSSK
       190        200        210        220        230        240
GVDFGLSILW FLIFTPCAFL CWYRPIYKAF RSDNSFSFFV FFFVFFCQIG IYIIQLVGIP
       250        260        270        280        290        300
GLGDSGWIAA LSTLDNHSLA ISVIMMVVAG FFTLCAVLSV FLLQRVHSLY RRTGASFQQA
       310        320
QEEFSQGIFS SRTFHRAASS AAQGAFQGN

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 5 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O15127-1-unknown	MSAFDT...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O15127-41-unknown	SETNAA...	41	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000455377
O15127-77-	VVSAAQ...	77		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
O15127-77-	VVSAAQ...	77		Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
O15127-77-	VVSAAQ...	77		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
O15127-77-	VVSAAQ...	77		Subtiligase Based Positive Selection		Wells	THP_untreated	23264352
O15127-77-unknown	VVSAAQ...	77		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
O15127-77-unknown	VVSAAQ...	77		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
O15127-151-unknown	MLYYLW...	151	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000454464

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...YKAFRS	211	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000457564
...DNSFSF	217	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000457890
...IPGLGD	243	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000454464
...AFQGN	329	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...AFQGN	329		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...AFQGN	329		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...AFQGN	329		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...AFQGN	329		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)