TopFIND 4.0

O15178: T-box transcription factor T {ECO:0000305}

General Information

Protein names
- T-box transcription factor T {ECO:0000305}
- Brachyury protein {ECO:0000305}
- Protein T
Gene names T
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID O15178

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSSPGTESAG KSLQYRVDHL LSAVENELQA GSEKGDPTER ELRVGLEESE LWLRFKELTN 
        70         80         90        100        110        120 
EMIVTKNGRR MFPVLKVNVS GLDPNAMYSF LLDFVAADNH RWKYVNGEWV PGGKPEPQAP 
       130        140        150        160        170        180 
SCVYIHPDSP NFGAHWMKAP VSFSKVKLTN KLNGGGQIML NSLHKYEPRI HIVRVGGPQR 
       190        200        210        220        230        240 
MITSHCFPET QFIAVTAYQN EEITALKIKY NPFAKAFLDA KERSDHKEMM EEPGDSQQPG 
       250        260        270        280        290        300 
YSQWGWLLPG TSTLCPPANP HPQFGGALSL PSTHSCDRYP TLRSHRSSPY PSPYAHRNNS 
       310        320        330        340        350        360 
PTYSDNSPAC LSMLQSHDNW SSLGMPAHPS MLPVSHNASP PTSSSQYPSL WSVSNGAVTP 
       370        380        390        400        410        420 
GSQAAAVSNG LGAQFFRGSP AHYTPLTHPV SAPSSSGSPL YEGAAAATDI VDSQYDAAAQ 
       430    
GRLIASWTPV SPPSM

Isoforms

- Isoform 2 of Brachyury protein - Isoform 2 of T-box transcription factor T

Sequence View

        10         20         30         40         50         60 
MSSPGTESAG KSLQYRVDHL LSAVENELQA GSEKGDPTER ELRVGLEESE LWLRFKELTN 
        70         80         90        100        110        120 
EMIVTKNGRR MFPVLKVNVS GLDPNAMYSF LLDFVAADNH RWKYVNGEWV PGGKPEPQAP 
       130        140        150        160        170        180 
SCVYIHPDSP NFGAHWMKAP VSFSKVKLTN KLNGGGQIML NSLHKYEPRI HIVRVGGPQR 
       190        200        210        220        230        240 
MITSHCFPET QFIAVTAYQN EEITALKIKY NPFAKAFLDA KERSDHKEMM EEPGDSQQPG 
       250        260        270        280        290        300 
YSQWGWLLPG TSTLCPPANP HPQFGGALSL PSTHSCDRYP TLRSHRSSPY PSPYAHRNNS 
       310        320        330        340        350        360 
PTYSDNSPAC LSMLQSHDNW SSLGMPAHPS MLPVSHNASP PTSSSQYPSL WSVSNGAVTP 
       370        380        390        400        410        420 
GSQAAAVSNG LGAQFFRGSP AHYTPLTHPV SAPSSSGSPL YEGAAAATDI VDSQYDAAAQ 
       430    
GRLIASWTPV SPPSM         10         20         30         40         50         60 
MSSPGTESAG KSLQYRVDHL LSAVENELQA GSEKGDPTER ELRVGLEESE LWLRFKELTN 
        70         80         90        100        110        120 
EMIVTKNGRR MFPVLKVNVS GLDPNAMYSF LLDFVAADNH RWKYVNGEWV PGGKPEPQAP 
       130        140        150        160        170        180 
SCVYIHPDSP NFGAHWMKAP VSFSKVKLTN KLNGGGQIML NSLHKYEPRI HIVRVGGPQR 
       190        200        210        220        230        240 
MITSHCFPET QFIAVTAYQN EEITALKIKY NPFAKAFLDA KERSDHKEMM EEPGDSQQPG 
       250        260        270        280        290        300 
YSQWGWLLPG TSTLCPPANP HPQFGGALSL PSTHSCDRYP TLRSHRSSPY PSPYAHRNNS 
       310        320        330        340        350        360 
PTYSDNSPAC LSMLQSHDNW SSLGMPAHPS MLPVSHNASP PTSSSQYPSL WSVSNGAVTP 
       370        380        390        400        410        420 
GSQAAAVSNG LGAQFFRGSP AHYTPLTHPV SAPSSSGSPL YEGAAAATDI VDSQYDAAAQ 
       430    
GRLIASWTPV SPPSM



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O15178-1-unknown MSSPGT... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    O15178-1-unknown MSSPGT... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt68585

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...SPPSM 435 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...SPPSM 435 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt64203

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)