TopFIND 4.0

O15198: Mothers against decapentaplegic homolog 9

General Information

Protein names
- Mothers against decapentaplegic homolog 9
- MAD homolog 9
- Mothers against DPP homolog 9
- Madh6
- SMAD family member 9
- SMAD 9
- Smad9
Gene names SMAD9
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID O15198

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MHSTTPISSL FSFTSPAVKR LLGWKQGDEE EKWAEKAVDS LVKKLKKKKG AMDELERALS 
        70         80         90        100        110        120 
CPGQPSKCVT IPRSLDGRLQ VSHRKGLPHV IYCRVWRWPD LQSHHELKPL ECCEFPFGSK 
       130        140        150        160        170        180 
QKEVCINPYH YRRVETPVLP PVLVPRHSEY NPQLSLLAKF RSASLHSEPL MPHNATYPDS 
       190        200        210        220        230        240 
FQQPPCSALP PSPSHAFSQS PCTASYPHSP GSPSEPESPY QHSVDTPPLP YHATEASETQ 
       250        260        270        280        290        300 
SGQPVDATAD RHVVLSIPNG DFRPVCYEEP QHWCSVAYYE LNNRVGETFQ ASSRSVLIDG 
       310        320        330        340        350        360 
FTDPSNNRNR FCLGLLSNVN RNSTIENTRR HIGKGVHLYY VGGEVYAECV SDSSIFVQSR 
       370        380        390        400        410        420 
NCNYQHGFHP ATVCKIPSGC SLKVFNNQLF AQLLAQSVHH GFEVVYELTK MCTIRMSFVK 
       430        440        450        460    
GWGAEYHRQD VTSTPCWIEI HLHGPLQWLD KVLTQMGSPH NPISSVS

Isoforms

- Isoform B of Mothers against decapentaplegic homolog 9

Sequence View

        10         20         30         40         50         60 
MHSTTPISSL FSFTSPAVKR LLGWKQGDEE EKWAEKAVDS LVKKLKKKKG AMDELERALS 
        70         80         90        100        110        120 
CPGQPSKCVT IPRSLDGRLQ VSHRKGLPHV IYCRVWRWPD LQSHHELKPL ECCEFPFGSK 
       130        140        150        160        170        180 
QKEVCINPYH YRRVETPVLP PVLVPRHSEY NPQLSLLAKF RSASLHSEPL MPHNATYPDS 
       190        200        210        220        230        240 
FQQPPCSALP PSPSHAFSQS PCTASYPHSP GSPSEPESPY QHSVDTPPLP YHATEASETQ 
       250        260        270        280        290        300 
SGQPVDATAD RHVVLSIPNG DFRPVCYEEP QHWCSVAYYE LNNRVGETFQ ASSRSVLIDG 
       310        320        330        340        350        360 
FTDPSNNRNR FCLGLLSNVN RNSTIENTRR HIGKGVHLYY VGGEVYAECV SDSSIFVQSR 
       370        380        390        400        410        420 
NCNYQHGFHP ATVCKIPSGC SLKVFNNQLF AQLLAQSVHH GFEVVYELTK MCTIRMSFVK 
       430        440        450        460    
GWGAEYHRQD VTSTPCWIEI HLHGPLQWLD KVLTQMGSPH NPISSVS



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O15198-1-unknown MHSTTP... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    O15198-1-unknown MHSTTP... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt89986

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...ISSVS 467 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...ISSVS 467 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt85604

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)