O15232: Matrilin-3

General Information

Protein names	- Matrilin-3
Gene names	MATN3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O15232

4 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPRPAPARRL PGLLLLLWPL LLLPSAAPDP VARPGFRRLE TRGPGGSPGR RPSPAAPDGA
        70         80         90        100        110        120
PASGTSEPGR ARGAGVCKSR PLDLVFIIDS SRSVRPLEFT KVKTFVSRII DTLDIGPADT
       130        140        150        160        170        180
RVAVVNYAST VKIEFQLQAY TDKQSLKQAV GRITPLSTGT MSGLAIQTAM DEAFTVEAGA
       190        200        210        220        230        240
REPSSNIPKV AIIVTDGRPQ DQVNEVAARA QASGIELYAV GVDRADMASL KMMASEPLEE
       250        260        270        280        290        300
HVFYVETYGV IEKLSSRFQE TFCALDPCVL GTHQCQHVCI SDGEGKHHCE CSQGYTLNAD
       310        320        330        340        350        360
KKTCSALDRC ALNTHGCEHI CVNDRSGSYH CECYEGYTLN EDRKTCSAQD KCALGTHGCQ
       370        380        390        400        410        420
HICVNDRTGS HHCECYEGYT LNADKKTCSV RDKCALGSHG CQHICVSDGA ASYHCDCYPG
       430        440        450        460        470        480
YTLNEDKKTC SATEEARRLV STEDACGCEA TLAFQDKVSS YLQRLNTKLD DILEKLKINE

YGQIHR

Isoforms

- Isoform 2 of Matrilin-3

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
O15232-1-unknown	MPRPAP...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt80482
O15232-29-unknown	DPVARP...	29	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O15232-29-unknown	DPVARP...	29	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt114556
O15232-99-unknown	FTKVKT...	99	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC311
O15232-99-unknown	FTKVKT...	99	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt142339
O15232-436-unknown	ARRLVS...	436	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC313
O15232-436-unknown	ARRLVS...	436	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt151904

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...VRPLEF	98	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC311
...VRPLEF	98	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt125530
...SATEEA	435	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC313
...SATEEA	435	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt135312
...GQIHR	486	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...GQIHR	486	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt76100

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
ATS4_HUMAN	98	PLEF.\|.FTKV	inferred from experiment	unknown	MEROPS	Tortorella MD	Hills R et al.:Identification of an ADAMTS-4 c... (M12.221)	17311924,
ATS4_HUMAN	435	TEEA.\|.ARRL	inferred from experiment	unknown	MEROPS	Tortorella MD	Hills R et al.:Identification of an ADAMTS-4 c... (M12.221)	17311924,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)