O15397: Importin-8

General Information

Protein names	- Importin-8 - Imp8 - Ran-binding protein 8 - RanBP8
Gene names	IPO8
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O15397

2 N-termini

6 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDLNRIIQAL KGTIDPKLRI AAENELNQSY KIINFAPSLL RIIVSDHVEF PVRQAAAIYL
        70         80         90        100        110        120
KNMVTQYWPD REPPPGEAIF PFNIHENDRQ QIRDNIVEGI IRSPDLVRVQ LTMCLRAIIK
       130        140        150        160        170        180
HDFPGHWPGV VDKIDYYLQS QSSASWLGSL LCLYQLVKTY EYKKAEEREP LIIAMQIFLP
       190        200        210        220        230        240
RIQQQIVQLL PDSSYYSVLL QKQILKIFYA LVQYALPLQL VNNQTMTTWM EIFRTIIDRT
       250        260        270        280        290        300
VPPETLHIDE DDRPELVWWK CKKWALHIVA RLFERYGSPG NVTKEYFEFS EFFLKTYAVG
       310        320        330        340        350        360
IQQVLLKILD QYRQKEYVAP RVLQQAFNYL NQGVVHSITW KQMKPHIQNI SEDVIFSVMC
       370        380        390        400        410        420
YKDEDEELWQ EDPYEYIRMK FDIFEDYASP TTAAQTLLYT AAKKRKEVLP KMMAFCYQIL
       430        440        450        460        470        480
TDPNFDPRKK DGALHVIGSL AEILLKKSLF KDQMELFLQN HVFPLLLSNL GYLRARSCWV
       490        500        510        520        530        540
LHAFSSLKFH NELNLRNAVE LAKKSLIEDK EMPVKVEAAL ALQSLISNQI QAKEYMKPHV
       550        560        570        580        590        600
RPIMQELLHI VRETENDDVT NVIQKMICEY SQEVASIAVD MTQHLAEIFG KVLQSDEYEE
       610        620        630        640        650        660
VEDKTVMAMG ILHTIDTILT VVEDHKEITQ QLENICLRII DLVLQKHVIE FYEEILSLAY
       670        680        690        700        710        720
SLTCHSISPQ MWQLLGILYE VFQQDCFEYF TDMMPLLHNY VTIDTDTLLS NAKHLEILFT
       730        740        750        760        770        780
MCRKVLCGDA GEDAECHAAK LLEVIILQCK GRGIDQCIPL FVQLVLERLT RGVKTSELRT
       790        800        810        820        830        840
MCLQVAIAAL YYNPDLLLHT LERIQLPHNP GPITVQFINQ WMNDTDCFLG HHDRKMCIIG
       850        860        870        880        890        900
LSILLELQNR PPAVDAVVGQ IVPSILFLFL GLKQVCATRQ LVNREDRSKA EKADMEENEE
       910        920        930        940        950        960
ISSDEEETNV TAQAMQSNNG RGEDEEEEDD DWDEEVLEET ALEGFSTPLD LDNSVDEYQF
       970        980        990       1000       1010       1020
FTQALITVQS RDAAWYQLLM APLSEDQRTA LQEVYTLAEH RRTVAEAKKK IEQQGGFTFE
      1030
NKGVLSAFNF GTVPSNN

Isoforms

- Isoform 2 of Importin-8

Sequence View

        10         20         30         40         50         60
MDLNRIIQAL KGTIDPKLRI AAENELNQSY KIINFAPSLL RIIVSDHVEF PVRQAAAIYL
        70         80         90        100        110        120
KNMVTQYWPD REPPPGEAIF PFNIHENDRQ QIRDNIVEGI IRSPDLVRVQ LTMCLRAIIK
       130        140        150        160        170        180
HDFPGHWPGV VDKIDYYLQS QSSASWLGSL LCLYQLVKTY EYKKAEEREP LIIAMQIFLP
       190        200        210        220        230        240
RIQQQIVQLL PDSSYYSVLL QKQILKIFYA LVQYALPLQL VNNQTMTTWM EIFRTIIDRT
       250        260        270        280        290        300
VPPETLHIDE DDRPELVWWK CKKWALHIVA RLFERYGSPG NVTKEYFEFS EFFLKTYAVG
       310        320        330        340        350        360
IQQVLLKILD QYRQKEYVAP RVLQQAFNYL NQGVVHSITW KQMKPHIQNI SEDVIFSVMC
       370        380        390        400        410        420
YKDEDEELWQ EDPYEYIRMK FDIFEDYASP TTAAQTLLYT AAKKRKEVLP KMMAFCYQIL
       430        440        450        460        470        480
TDPNFDPRKK DGALHVIGSL AEILLKKSLF KDQMELFLQN HVFPLLLSNL GYLRARSCWV
       490        500        510        520        530        540
LHAFSSLKFH NELNLRNAVE LAKKSLIEDK EMPVKVEAAL ALQSLISNQI QAKEYMKPHV
       550        560        570        580        590        600
RPIMQELLHI VRETENDDVT NVIQKMICEY SQEVASIAVD MTQHLAEIFG KVLQSDEYEE
       610        620        630        640        650        660
VEDKTVMAMG ILHTIDTILT VVEDHKEITQ QLENICLRII DLVLQKHVIE FYEEILSLAY
       670        680        690        700        710        720
SLTCHSISPQ MWQLLGILYE VFQQDCFEYF TDMMPLLHNY VTIDTDTLLS NAKHLEILFT
       730        740        750        760        770        780
MCRKVLCGDA GEDAECHAAK LLEVIILQCK GRGIDQCIPL FVQLVLERLT RGVKTSELRT
       790        800        810        820        830        840
MCLQVAIAAL YYNPDLLLHT LERIQLPHNP GPITVQFINQ WMNDTDCFLG HHDRKMCIIG
       850        860        870        880        890        900
LSILLELQNR PPAVDAVVGQ IVPSILFLFL GLKQVCATRQ LVNREDRSKA EKADMEENEE
       910        920        930        940        950        960
ISSDEEETNV TAQAMQSNNG RGEDEEEEDD DWDEEVLEET ALEGFSTPLD LDNSVDEYQF
       970        980        990       1000       1010       1020
FTQALITVQS RDAAWYQLLM APLSEDQRTA LQEVYTLAEH RRTVAEAKKK IEQQGGFTFE
      1030
NKGVLSAFNF GTVPSNN

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
O15397-1-unknown	MDLNRI...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O15397-63-unknown	MVTQYW...	63	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000440979
O15397-63-unknown	MVTQYW...	63	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000444050

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...YLKNMV	63	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000446254
...QIRDNI	95	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000444050
...SPDLVR	107	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000439413
...YALVQY	213	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000440979
...NISEDV	353	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000439556
...VPSNN	1037	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...VPSNN	1037	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt73631

TopFIND

O15397: Importin-8

General Information

2

N-termini

6

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

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Protein Neighborhood

Domains & Features

2 N-termini - 6 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates