O15504: Nucleoporin-like protein 2

General Information

Protein names	- Nucleoporin-like protein 2 - NLP-1 - NUP42 homolog - Nucleoporin hCG1
Gene names	NUPL2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O15504

5 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Nucleoporin-like protein 2 - Isoform 3 of Nucleoporin-like protein 2 - Isoform 2 of Nucleoporin NUP42 - Isoform 3 of Nucleoporin NUP42

Sequence View

        10         20         30         40         50         60
MAICQFFLQG RCRFGDRCWN EHPGARGAGG GRQQPQQQPS GNNRRGWNTT SQRYSNVIQP
        70         80         90        100        110        120
SSFSKSTPWG GSRDQEKPYF SSFDSGASTN RKEGFGLSEN PFASLSPDEQ KDEKKLLEGI
       130        140        150        160        170        180
VKDMEVWESS GQWMFSVYSP VKKKPNISGF TDISPEELRL EYHNFLTSNN LQSYLNSVQR
       190        200        210        220        230        240
LINQWRNRVN ELKSLNISTK VALLSDVKDG VNQAAPAFGF GSSQAATFMS PGFPVNNSSS
       250        260        270        280        290        300
DNAQNFSFKT NSGFAAASSG SPAGFGSSPA FGAAASTSSG ISTSAPAFGF GKPEVTSAAS
       310        320        330        340        350        360
FSFKSPAASS FGSPGFSGLP ASLATGPVRA PVAPAFGGGS SVAGFGSPGS HSHTAFSKPS
       370        380        390        400        410        420
SDTFGNSSIS TSLSASSSII ATDNVLFTPR DKLTVEELEQ FQSKKFTLGK IPLKPPPLEL

LNV         10         20         30         40         50         60
MAICQFFLQG RCRFGDRCWN EHPGARGAGG GRQQPQQQPS GNNRRGWNTT SQRYSNVIQP
        70         80         90        100        110        120
SSFSKSTPWG GSRDQEKPYF SSFDSGASTN RKEGFGLSEN PFASLSPDEQ KDEKKLLEGI
       130        140        150        160        170        180
VKDMEVWESS GQWMFSVYSP VKKKPNISGF TDISPEELRL EYHNFLTSNN LQSYLNSVQR
       190        200        210        220        230        240
LINQWRNRVN ELKSLNISTK VALLSDVKDG VNQAAPAFGF GSSQAATFMS PGFPVNNSSS
       250        260        270        280        290        300
DNAQNFSFKT NSGFAAASSG SPAGFGSSPA FGAAASTSSG ISTSAPAFGF GKPEVTSAAS
       310        320        330        340        350        360
FSFKSPAASS FGSPGFSGLP ASLATGPVRA PVAPAFGGGS SVAGFGSPGS HSHTAFSKPS
       370        380        390        400        410        420
SDTFGNSSIS TSLSASSSII ATDNVLFTPR DKLTVEELEQ FQSKKFTLGK IPLKPPPLEL

LNV         10         20         30         40         50         60
MAICQFFLQG RCRFGDRCWN EHPGARGAGG GRQQPQQQPS GNNRRGWNTT SQRYSNVIQP
        70         80         90        100        110        120
SSFSKSTPWG GSRDQEKPYF SSFDSGASTN RKEGFGLSEN PFASLSPDEQ KDEKKLLEGI
       130        140        150        160        170        180
VKDMEVWESS GQWMFSVYSP VKKKPNISGF TDISPEELRL EYHNFLTSNN LQSYLNSVQR
       190        200        210        220        230        240
LINQWRNRVN ELKSLNISTK VALLSDVKDG VNQAAPAFGF GSSQAATFMS PGFPVNNSSS
       250        260        270        280        290        300
DNAQNFSFKT NSGFAAASSG SPAGFGSSPA FGAAASTSSG ISTSAPAFGF GKPEVTSAAS
       310        320        330        340        350        360
FSFKSPAASS FGSPGFSGLP ASLATGPVRA PVAPAFGGGS SVAGFGSPGS HSHTAFSKPS
       370        380        390        400        410        420
SDTFGNSSIS TSLSASSSII ATDNVLFTPR DKLTVEELEQ FQSKKFTLGK IPLKPPPLEL

LNV         10         20         30         40         50         60
MAICQFFLQG RCRFGDRCWN EHPGARGAGG GRQQPQQQPS GNNRRGWNTT SQRYSNVIQP
        70         80         90        100        110        120
SSFSKSTPWG GSRDQEKPYF SSFDSGASTN RKEGFGLSEN PFASLSPDEQ KDEKKLLEGI
       130        140        150        160        170        180
VKDMEVWESS GQWMFSVYSP VKKKPNISGF TDISPEELRL EYHNFLTSNN LQSYLNSVQR
       190        200        210        220        230        240
LINQWRNRVN ELKSLNISTK VALLSDVKDG VNQAAPAFGF GSSQAATFMS PGFPVNNSSS
       250        260        270        280        290        300
DNAQNFSFKT NSGFAAASSG SPAGFGSSPA FGAAASTSSG ISTSAPAFGF GKPEVTSAAS
       310        320        330        340        350        360
FSFKSPAASS FGSPGFSGLP ASLATGPVRA PVAPAFGGGS SVAGFGSPGS HSHTAFSKPS
       370        380        390        400        410        420
SDTFGNSSIS TSLSASSSII ATDNVLFTPR DKLTVEELEQ FQSKKFTLGK IPLKPPPLEL

LNV

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O15504-1-unknown	MAICQF...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O15504-1-unknown	MAICQF...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt83562
O15504-2-unknown	AICQFF...	2		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
O15504-2-unknown	AICQFF...	2	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt162790
O15504-55-unknown	SNVIQP...	55		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
O15504-55-unknown	SNVIQP...	55	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160010
O15504-55-	SNVIQP...	55		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
O15504-229-unknown	MSPGFP...	229	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt83563

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...ELLNV	423	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...ELLNV	423	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt79181

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)