O15528: 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial
| Protein names | - 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial - 1.14.15.18 {ECO:0000269|PubMed:10518789} - 25-OHD-1 alpha-hydroxylase - 25-hydroxyvitamin D(3) 1-alpha-hydroxylase - VD3 1A hydroxylase - Calcidiol 1-monooxygenase - Cytochrome P450 subfamily XXVIIB polypeptide 1 - Cytochrome P450C1 alpha - Cytochrome P450VD1-alpha - Cytochrome p450 27B1 |
|---|---|
| Gene names | CYP27B1 |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | O15528 |
2
N-termini
3
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MTQTLKYASR VFHRVRWAPE LGASLGYREY HSARRSLADI PGPSTPSFLA ELFCKGGLSR
70 80 90 100 110 120
LHELQVQGAA HFGPVWLASF GTVRTVYVAA PALVEELLRQ EGPRPERCSF SPWTEHRRCR
130 140 150 160 170 180
QRACGLLTAE GEEWQRLRSL LAPLLLRPQA AARYAGTLNN VVCDLVRRLR RQRGRGTGPP
190 200 210 220 230 240
ALVRDVAGEF YKFGLEGIAA VLLGSRLGCL EAQVPPDTET FIRAVGSVFV STLLTMAMPH
250 260 270 280 290 300
WLRHLVPGPW GRLCRDWDQM FAFAQRHVER REAEAAMRNG GQPEKDLESG AHLTHFLFRE
310 320 330 340 350 360
ELPAQSILGN VTELLLAGVD TVSNTLSWAL YELSRHPEVQ TALHSEITAA LSPGSSAYPS
370 380 390 400 410 420
ATVLSQLPLL KAVVKEVLRL YPVVPGNSRV PDKDIHVGDY IIPKNTLVTL CHYATSRDPA
430 440 450 460 470 480
QFPEPNSFRP ARWLGEGPTP HPFASLPFGF GKRSCMGRRL AELELQMALA QILTHFEVQP
490 500
EPGAAPVRPK TRTVLVPERS INLQFLDR
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
2 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| O15528-0-unknown | RMTQTL... | 0 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| O15528-236-unknown | MAMPHW... | 236 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000449472 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...QMFAFA | 263 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000476959 | |||
| ...SRVPDK | 392 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000449472 | |||
| ...QFLDR | 508 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|