TopFIND 4.0

O15547: P2X purinoceptor 6

General Information

Protein names
- P2X purinoceptor 6
- P2X6
- ATP receptor
- P2XM
- Purinergic receptor
- Purinergic receptor P2X-like 1
Gene names P2RX6
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID O15547

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MCPQLAGAGS MGSPGATTGW GLLDYKTEKY VMTRNWRVGA LQRLLQFGIV VYVVGWALLA 
        70         80         90        100        110        120 
KKGYQERDLE PQFSIITKLK GVSVTQIKEL GNRLWDVADF VKPPQGENVF FLVTNFLVTP 
       130        140        150        160        170        180 
AQVQGRCPEH PSVPLANCWV DEDCPEGEGG THSHGVKTGQ CVVFNGTHRT CEIWSWCPVE 
       190        200        210        220        230        240 
SGVVPSRPLL AQAQNFTLFI KNTVTFSKFN FSKSNALETW DPTYFKHCRY EPQFSPYCPV 
       250        260        270        280        290        300 
FRIGDLVAKA GGTFEDLALL GGSVGIRVHW DCDLDTGDSG CWPHYSFQLQ EKSYNFRTAT 
       310        320        330        340        350        360 
HWWEQPGVEA RTLLKLYGIR FDILVTGQAG KFGLIPTAVT LGTGAAWLGV VTFFCDLLLL 
       370        380        390        400        410        420 
YVDREAHFYW RTKYEEAKAP KATANSVWRE LALASQARLA ECLRRSSAPA PTATAAGSQT 
       430        440    
QTPGWPCPSS DTHLPTHSGS L

Isoforms

- Isoform 2 of P2X purinoceptor 6

Sequence View

        10         20         30         40         50         60 
MCPQLAGAGS MGSPGATTGW GLLDYKTEKY VMTRNWRVGA LQRLLQFGIV VYVVGWALLA 
        70         80         90        100        110        120 
KKGYQERDLE PQFSIITKLK GVSVTQIKEL GNRLWDVADF VKPPQGENVF FLVTNFLVTP 
       130        140        150        160        170        180 
AQVQGRCPEH PSVPLANCWV DEDCPEGEGG THSHGVKTGQ CVVFNGTHRT CEIWSWCPVE 
       190        200        210        220        230        240 
SGVVPSRPLL AQAQNFTLFI KNTVTFSKFN FSKSNALETW DPTYFKHCRY EPQFSPYCPV 
       250        260        270        280        290        300 
FRIGDLVAKA GGTFEDLALL GGSVGIRVHW DCDLDTGDSG CWPHYSFQLQ EKSYNFRTAT 
       310        320        330        340        350        360 
HWWEQPGVEA RTLLKLYGIR FDILVTGQAG KFGLIPTAVT LGTGAAWLGV VTFFCDLLLL 
       370        380        390        400        410        420 
YVDREAHFYW RTKYEEAKAP KATANSVWRE LALASQARLA ECLRRSSAPA PTATAAGSQT 
       430        440    
QTPGWPCPSS DTHLPTHSGS L



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...HSGSL 441 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...HSGSL 441 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt79630

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)