TopFIND 4.0

O35350: Calpain-1 catalytic subunit {ECO:0000305}

General Information

Protein names
- Calpain-1 catalytic subunit {ECO:0000305}
- 3.4.22.52 {ECO:0000250|UniProtKB:P07384}
- Calcium-activated neutral proteinase 1 {ECO:0000250|UniProtKB:P07384}
- CANP 1 {ECO:0000250|UniProtKB:P07384}
- Calpain mu-type {ECO:0000250|UniProtKB:P07384}
- Calpain-1 large subunit {ECO:0000250|UniProtKB:P07384}
- Micromolar-calpain
- muCANP {ECO:0000250|UniProtKB:P07384}
Gene names Capn1
Organism Mus musculus
Protease Family
Protease ID C02.001
Chromosome location
UniProt ID O35350

2

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MTEELITPVY CTGVSAQVQK KRDKELGLGR HENAIKYLGQ DYETLRARCL QSGVLFQDEA 
        70         80         90        100        110        120 
FPPVSHSLGF KELGPHSSKT YGIKWKRPTE LMSNPQFIVD GATRTDICQG ALGDCWLLAA 
       130        140        150        160        170        180 
IASLTLNETI LHRVVPYGQS FQDGYAGIFH FQLWQFGEWV DVVIDDLLPT KDGKLVFVHS 
       190        200        210        220        230        240 
AQGNEFWSAL LEKAYAKVNG SYEALSGGCT SEAFEDFTGG VTEWYDLQKA PSDLYQIILK 
       250        260        270        280        290        300 
ALERGSLLGC SINISDIRDL EAITFKNLVR GHAYSVTGAK QVTYQGQRVN LIRMRNPWGE 
       310        320        330        340        350        360 
VEWKGPWSDS SYEWNKVDPY EREQLRVKME DGEFWMSFRD FIREFTKLEI CNLTPDALKS 
       370        380        390        400        410        420 
RTLRNWNTTF YEGTWRRGST AGGCRNYPAT FWVNPQFKIR LEEVDDADDY DNRESGCSFL 
       430        440        450        460        470        480 
LALMQKHRRR ERRFGRDMET IGFAVYQVPR ELAGQPVHLK RDFFLANASR AQSEHFINLR 
       490        500        510        520        530        540 
EVSNRIRLPP GEYIVVPSTF EPNKEGDFLL RFFSEKKAGT QELDDQIQAN LPDEKVLSEE 
       550        560        570        580        590        600 
EIDDNFKTLF SKLAGDDMEI SVKELQTILN RIISKHKDLR TNGFSLESCR SMVNLMDRDG 
       610        620        630        640        650        660 
NGKLGLVEFN ILWNRIRNYL TIFRKFDLDK SGSMSAYEMR MAIEAAGFKL NKKLHELIIT 
       670        680        690        700        710    
RYSEPDLAVD FDNFVCCLVR LETMFRFFKL LDTDLDGVVT FDLFKWLQLT MFA

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)