O35379: Multidrug resistance-associated protein 1 {ECO:0000305}

General Information

Protein names	- Multidrug resistance-associated protein 1 {ECO:0000305} - 7.6.2.2 {ECO:0000269\|PubMed:9281595} - ATP-binding cassette sub-family C member 1 - Glutathione-S-conjugate-translocating ATPase ABCC1 {ECO:0000305} - 7.6.2.3 {ECO:0000269\|PubMed:9359705} - Leukotriene C(4) transporter - LTC4 transporter
Gene names	Abcc1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	O35379

1 N-termini

4 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MALRSFCSAD GSDPLWDWNV TWHTSNPDFT KCFQNTVLTW VPCFYLWSCF PLYFFYLSRH
        70         80         90        100        110        120
DRGYIQMTHL NKTKTALGFF LWIICWADLF YSFWERSQGV LRAPVLLVSP TLLGITMLLA
       130        140        150        160        170        180
TFLIQLERRK GVQSSGIMLT FWLVALLCAL AILRSKIISA LKKDAHVDVF RDSTFYLYFT
       190        200        210        220        230        240
LVLVQLVLSC FSDCSPLFSE TVHDRNPCPE SSASFLSRIT FWWITGMMVH GYRQPLESSD
       250        260        270        280        290        300
LWSLNKEDTS EEVVPVLVNN WKKECDKSRK QPVRIVYAPP KDPSKPKGSS QLDVNEEVEA
       310        320        330        340        350        360
LIVKSPHKDR EPSLFKVLYK TFGPYFLMSF LYKALHDLMM FAGPKILELI INFVNDREAP
       370        380        390        400        410        420
DWQGYFYTAL LFVSACLQTL ALHQYFHICF VSGMRIKTAV VGAVYRKALL ITNAARKSST
       430        440        450        460        470        480
VGEIVNLMSV DAQRFMDLAT YINMIWSAPL QVILALYFLW LSLGPSVLAG VAVMILMVPL
       490        500        510        520        530        540
NAVMAMKTKT YQVAHMKSKD NRIKLMNEIL NGIKVLKLYA WELAFQDKVM SIRQEELKVL
       550        560        570        580        590        600
KKSAYLAAVG TFTWVCTPFL VALSTFAVFV TVDERNILDA KKAFVSLALF NILRFPLNIL
       610        620        630        640        650        660
PMVISSIVQA SVSLKRLRIF LSHEELEPDS IERRSIKSGE GNSITVKNAT FTWARGEPPT
       670        680        690        700        710        720
LNGITFSIPE GALVAVVGQV GCGKSSLLSA LLAEMDKVEG HVTLKGSVAY VPQQAWIQND
       730        740        750        760        770        780
SLRENILFGH PLQENYYKAV MEACALLPDL EILPSGDRTE IGEKGVNLSG GQKQRVSLAR
       790        800        810        820        830        840
AVYSNSDIYL FDDPLSAVDA HVGKHIFEKV VGPMGLLKNK TRILVTHGIS YLPQVDVIIV
       850        860        870        880        890        900
MSGGKISEMG SYQELLDRDG AFAEFLRTYA NAEQDLASED DSVSGSGKES KPVENGMLVT
       910        920        930        940        950        960
DTVGKHLQRH LSNSSSHSGD TSQQHSSIAE LQKAGAKEET WKLMEADKAQ TGQVQLSVYW
       970        980        990       1000       1010       1020
NYMKAIGLFI TFLSIFLFLC NHVSALASNY WLSLWTDDPP VVNGTQANRN FRLSVYGALG
      1030       1040       1050       1060       1070       1080
ILQGAAIFGY SMAVSIGGIF ASRRLHLDLL YNVLRSPMSF FERTPSGNLV NRFSKELDTV
      1090       1100       1110       1120       1130       1140
DSMIPQVIKM FMGSLFSVIG AVIIILLATP IAAVIIPPLG LVYFFVQRFY VASSRQLKRL
      1150       1160       1170       1180       1190       1200
ESVSRSPVYS HFNETLLGVS VIRAFEEQER FIHQSDLKVD ENQKAYYPSI VANRWLAVRL
      1210       1220       1230       1240       1250       1260
ECVGNCIVLF AALFAVISRH SLSAGLVGLS VSYSLQITAY LNWLVRMSSE METNIVAVER
      1270       1280       1290       1300       1310       1320
LKEYSETEKE APWQIQETAP PSTWPHSGRV EFRDYCLRYR EDLDLVLKHI NVTIEGGEKV
      1330       1340       1350       1360       1370       1380
GIVGRTGAGK SSLTLGLFRI NESAEGEIII DGVNIAKIGL HNLRFKITII PQDPVLFSGS
      1390       1400       1410       1420       1430       1440
LRMNLDPFSQ YSDEEVWMAL ELAHLKGFVS ALPDKLNHEC AEGGENLSVG QRQLVCLARA
      1450       1460       1470       1480       1490       1500
LLRKTKILVL DEATAAVDLE TDNLIQSTIR TQFEDCTVLT IAHRLNTIMD YTRVIVLDKG
      1510       1520
EVRECGAPSE LLQQRGIFYS MAKDAGLV

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

1 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O35379-1-unknown	MALRSF...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LGITML	117	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000116726
...LYFTLV	181	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000115763
...ESSDLW	241	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000120933
...DAGLV	1528	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)