TopFIND 4.0

O35600: Retinal-specific phospholipid-transporting ATPase ABCA4 {ECO:0000250|UniProtKB:P78363}

General Information

Protein names
- Retinal-specific phospholipid-transporting ATPase ABCA4 {ECO:0000250|UniProtKB:P78363}
- 7.6.2.1 {ECO:0000250|UniProtKB:P78363}
- ATP-binding cassette sub-family A member 4
- RIM ABC transporter
- RIM protein
- RmP
- Retinal-specific ATP-binding cassette transporter
Gene names Abca4
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID O35600

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGFLRQIQLL LWKNWTLRKR QKIRFVVELV WPLSLFLVLI WLRNANPLYS QHECHFPNKA 
        70         80         90        100        110        120 
MPSAGLLPWL QGIFCNMNNP CFQNPTPGES PGTVSNYNNS ILARVYRDFQ ELFMDTPEVQ 
       130        140        150        160        170        180 
HLGQVWAELR TLSQFMDTLR THPERFAGRG LQIRDILKDE EALTLFLMRN IGLSDSVAHL 
       190        200        210        220        230        240 
LVNSQVRVEQ FAYGVPDLEL TDIACSEALL QRFIIFSQRR GAQTVRDALC PLSQVTLQWI 
       250        260        270        280        290        300 
EDTLYADVDF FKLFHVLPTL LDSSSQGINL RFWGGILSDL SPRMQKFIHR PSVQDLLWVS 
       310        320        330        340        350        360 
RPLLQNGGPE TFTQLMSILS DLLCGYPEGG GSRVFSFNWY EDNNYKAFLG IDSTRKDPAY 
       370        380        390        400        410        420 
SYDKRTTSFC NSLIQSLESN PLTKIAWRAA KPLLMGKILF TPDSPAARRI MKNANSTFEE 
       430        440        450        460        470        480 
LDRVRKLVKA WEEVGPQIWY FFEKSTQMTV IRDTLQHPTV KDFINRQLGE EGITTEAVLN 
       490        500        510        520        530        540 
FFSNGPQEKQ ADDMTSFDWR DIFNITDRFL RLANQYLECL VLDKFESYDD EVQLTQRALS 
       550        560        570        580        590        600 
LLEENRFWAG VVFPGMYPWA SSLPPHVKYK IRMDIDVVEK TNKIKDRYWD SGPRADPVED 
       610        620        630        640        650        660 
FRYIWGGFAY LQDMVEQGIV KSQMQAEPPI GVYLQQMPYP CFVDDSFMII LNRCFPIFMV 
       670        680        690        700        710        720 
LAWIYSVSMT VKGIVLEKEL RLKETLKNQG VSNAVIWCTW FLDSFSIMAL SIFLLTLFIM 
       730        740        750        760        770        780 
HGRILHYSDP FILFLFLLAF ATATIMQSFL LSTLFSKASL AAACSGVIYF TLYLPHVLCF 
       790        800        810        820        830        840 
AWQDRMTADL KTTVSLLSSV AFGFGTEYLV RFEEQGLGLQ WSNIGKSPLE GDEFSFLLSM 
       850        860        870        880        890        900 
KMMLLDAALY GLLAWYLDQV FPGDYGTPLP WYFLLQESYW LGGEGCSTRE ERALEKTEPL 
       910        920        930        940        950        960 
TEEMEDPEHP EGMNDSFFER ELPGLVPGVC VKNLVKVFEP SGRPAVDRLN ITFYENQITA 
       970        980        990       1000       1010       1020 
FLGHNGAGKT TTLSILTGLL PPTSGTVLIG GKDIETNLDV VRQSLGMCPQ HNILFHHLTV 
      1030       1040       1050       1060       1070       1080 
AEHILFYAQL KGRSWEEAQL EMEAMLEDTG LHHKRNEEAQ DLSGGMQRKL SVAIAFVGDS 
      1090       1100       1110       1120       1130       1140 
KVVVLDEPTS GVDPYSRRSI WDLLLKYRSG RTIIMSTHHM DEADLLGDRI AIISQGRLYC 
      1150       1160       1170       1180       1190       1200 
SGTPLFLKNC FGTGFYLTLV RKMKNIQSQR GGCEGVCSCT SKGFSTRCPT RVDEITEEQV 
      1210       1220       1230       1240       1250       1260 
LDGDVQELMD LVYHHVPEAK LVECIGQELI FLLPNKNFKQ RAYASLFREL EETLADLGLS 
      1270       1280       1290       1300       1310       1320 
SFGISDTPLE EIFLKVTEDA GAGSMFVGGA QQKREQAGLR HPCSAPTEKL RQYAQAPHTC 
      1330       1340       1350       1360       1370       1380 
SPGQVDPPKG QPSPEPEDPG VPFNTGARLI LQHVQALLVK RFHHTIRSRK DFVAQIVLPA 
      1390       1400       1410       1420       1430       1440 
TFVFLALMLS IIVPPFGEFP ALTLHPWMYG HQYTFFSMDE PNNEHLEVLA DVLLNRPGFG 
      1450       1460       1470       1480       1490       1500 
NRCLKEEWLP EYPCINATSW KTPSVSPNIT HLFQKQKWTA AHPSPSCKCS TREKLTMLPE 
      1510       1520       1530       1540       1550       1560 
CPEGAGGLPP PQRTQRSTEV LQDLTNRNIS DYLVKTYPAL IRSSLKSKFW VNEQRYGGIS 
      1570       1580       1590       1600       1610       1620 
IGGKLPAIPI SGEALVGFLS GLGQMMNVSG GPVTREASKE MLDFLKHLET TDNIKVWFNN 
      1630       1640       1650       1660       1670       1680 
KGWHALVSFL NVAHNAILRA SLPRDRDPEE YGITVISQPL NLTKEQLSDI TVLTTSVDAV 
      1690       1700       1710       1720       1730       1740 
VAICVIFAMS FVPASFVLYL IQERVTKAKH LQFISGVSPT TYWLTNFLWD IMNYAVSAGL 
      1750       1760       1770       1780       1790       1800 
VVGIFIGFQK KAYTSPDNLP ALVSLLMLYG WAVIPMMYPA SFLFEVPSTA YVALSCANLF 
      1810       1820       1830       1840       1850       1860 
IGINSSAITF VLELFENNRT LLRFNAMLRK LLIVFPHFCL GRGLIDLALS QAVTDVYAQF 
      1870       1880       1890       1900       1910       1920 
GEEYSANPFQ WDLIGKNLVA MAIEGVVYFL LTLLIQHHFF LTRWIAEPAR EPVFDEDDDV 
      1930       1940       1950       1960       1970       1980 
AEERQRVMSG GNKTDILKLN ELTKVYSGSS SPAVDRLCVG VRPGECFGLL GVNGAGKTTT 
      1990       2000       2010       2020       2030       2040 
FKMLTGDTTV TSGDATVAGK SILTSISDVH QNMGYCPQFD AIDDLLTGRE HLYLYARLRG 
      2050       2060       2070       2080       2090       2100 
VPSKEIEKVA NWGIQSLGLS LYADRLAGTY SGGNKRKLST AIALTGCPPL LLLDEPTTGM 
      2110       2120       2130       2140       2150       2160 
DPQARRMLWN TIVSIIREGR AVVLTSHSME ECEALCTRLA IMVKGTFQCL GTIQHLKYKF 
      2170       2180       2190       2200       2210       2220 
GDGYIVTMKI KSPKDDLLPD LNPVEQFFQG NFPGSVQRER HHSMLQFQVP SSSLARIFQL 
      2230       2240       2250       2260       2270       2280 
LISHKDSLLI EEYSVTQTTL DQVFVNFAKQ QTETYDLPLH PRAAGASWQA KLEEKSGRLQ 
      2290       2300       2310    
TQEPLPAGSE QLANGSNPTA AEDKHTRSPQ 

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O35600-1-unknown MGFLRQ... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...TRSPQ 2310 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)