O35638: Cohesin subunit SA-2

General Information

Protein names	- Cohesin subunit SA-2 - SCC3 homolog 2 - Stromal antigen 2
Gene names	Stag2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	O35638

2 N-termini

5 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MIAAPEIPTD FNLLQESETH FSSDTDFEDI EGKNQKQGKG KTCKKGKKGP AEKGKSGNGG
        70         80         90        100        110        120
GKPPSGSNRM NGHHQQNGVE NMMLFEVVKM GKSAMQSVVD DWIESYKHDR DIALLDLINF
       130        140        150        160        170        180
FIQCSGCKGV VTAEMFRHMQ NSEIIRKMTE EFDEDSGDYP LTMAGPQWKK FKSSFCEFIG
       190        200        210        220        230        240
VLVRQCQYSI IYDEYMMDTV ISLLTGLSDS QVRAFRHTST LAAMKLMTAL VNVALNLSIN
       250        260        270        280        290        300
MDNTQRQYEA ERNKMIGKRA NERLELLLQK RKELQENQDE IENMMNAIFK GVFVHRYRDA
       310        320        330        340        350        360
IAEIRAICIE EIGIWMKMYS DAFLNDSYLK YVGWTMHDKQ GEVRLKCLTA LQGLYYNKEL
       370        380        390        400        410        420
NSKLELFTSR FKDRIVSMTL DKEYDVAVQA IKLLTLVLQS SEEVLTAEDC ENVYHLVYSA
       430        440        450        460        470        480
HRPVAVAAGE FLYKKLFSRR DPEEDGLMKR RGRQGPNANL VKTLVFFFLE SELHEHAAYL
       490        500        510        520        530        540
VDSMWDCATE LLKDWECMNS LLLEEPLSGE EALTDRQESA LIEIMLCTIR QAAECHPPVG
       550        560        570        580        590        600
RGTGKRVLTA KEKKTQLDDR TRITELFAVA LPQLLAKYSV DAEKVTNLLQ LPQYFDLEIY
       610        620        630        640        650        660
TTGRLEKHLD ALLRQIRNIV EKHTDTDVLE ACSKTYHALC NEEFTIFNRV DISRSQLIDE
       670        680        690        700        710        720
LADKFNRLLE DFLQEGEEPD EDDAYQVLST LKRITAFHNA HDLSKWDLFA CNYKLLKTGI
       730        740        750        760        770        780
ENGDMPEQIV IHALQCAHYV ILWQLAKITE STSTKEDLLR LKKQMRVFCQ ICQHYLTNVN
       790        800        810        820        830        840
TTVKEQAFTI LCDILMIFSH QIMSGGRDML EPLVYTPDSS LQSELLSFIL DHVFIEQDDD
       850        860        870        880        890        900
SNSADGQQED EASKIEALHK RRNLLAAFCK LIVYTVVEMN TAADIFKQYM KYYNDYGDII
       910        920        930        940        950        960
KETMSKTRQI DKIQCAKTLI LSLQQLFNEM IQENGYNFDR SSSTFSGIKE LARRFALTFG
       970        980        990       1000       1010       1020
LDQLKTREAI AMLHKDGIEF AFKEPNPQGE SHPPLNLAFL DILSEFSSKL LRQDKRTVYV
      1030       1040       1050       1060       1070       1080
YLEKFMTFQM SLRREDVWLP LMSYRNSLLA GGDDDTMSVI SGMSSRGSTV RSKKSKPSTG
      1090       1100       1110       1120       1130       1140
KRKVVEGMQL ALPEESSSSD SMWLSREQTL HTPVMMQTPQ LTSTIMREPK RLRPEDSFMS
      1150       1160       1170       1180       1190       1200
VYPMQAEHHQ TPLDYNRRGT SLMEDDEEPI VEDVMMSSEG RIEDLNEGMD FDTMDIDLPP
      1210       1220       1230
SKNRRERTEL KPDFFDPASI MDESVLGVSM F

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

2 N-termini - 5 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O35638-1-Acetylation	MIAAPE...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O35638-1058-unknown	SVISGM...	1058		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29524

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KQGKGK	40	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000119635
...QGKGKT	41	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000118567
...NSEIIR	145	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000120592
...DDDTMS	1057	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29524
...GVSMF	1231	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	1057	DTMS.\|.SVIS	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> STAG2_MOUSE @1057

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)