TopFIND 4.0

O43174: Cytochrome P450 26A1

General Information

Protein names
- Cytochrome P450 26A1
- 1.14.13.- {ECO:0000269|PubMed:26937021, ECO:0000269|PubMed:9228017, ECO:0000269|PubMed:9716180}
- Cytochrome P450 retinoic acid-inactivating 1
- Cytochrome P450RAI
- hP450RAI
- Retinoic acid 4-hydroxylase
- Retinoic acid-metabolizing cytochrome
Gene names CYP26A1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID O43174

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGLPALLASA LCTFVLPLLL FLAAIKLWDL YCVSGRDRSC ALPLPPGTMG FPFFGETLQM 
        70         80         90        100        110        120 
VLQRRKFLQM KRRKYGFIYK THLFGRPTVR VMGADNVRRI LLGEHRLVSV HWPASVRTIL 
       130        140        150        160        170        180 
GSGCLSNLHD SSHKQRKKVI MRAFSREALE CYVPVITEEV GSSLEQWLSC GERGLLVYPE 
       190        200        210        220        230        240 
VKRLMFRIAM RILLGCEPQL AGDGDSEQQL VEAFEEMTRN LFSLPIDVPF SGLYRGMKAR 
       250        260        270        280        290        300 
NLIHARIEQN IRAKICGLRA SEAGQGCKDA LQLLIEHSWE RGERLDMQAL KQSSTELLFG 
       310        320        330        340        350        360 
GHETTASAAT SLITYLGLYP HVLQKVREEL KSKGLLCKSN QDNKLDMEIL EQLKYIGCVI 
       370        380        390        400        410        420 
KETLRLNPPV PGGFRVALKT FELNGYQIPK GWNVIYSICD THDVAEIFTN KEEFNPDRFM 
       430        440        450        460        470        480 
LPHPEDASRF SFIPFGGGLR SCVGKEFAKI LLKIFTVELA RHCDWQLLNG PPTMKTSPTV 
       490    
YPVDNLPARF THFHGEI

Isoforms

- Isoform 2 of Cytochrome P450 26A1

Sequence View

        10         20         30         40         50         60 
MGLPALLASA LCTFVLPLLL FLAAIKLWDL YCVSGRDRSC ALPLPPGTMG FPFFGETLQM 
        70         80         90        100        110        120 
VLQRRKFLQM KRRKYGFIYK THLFGRPTVR VMGADNVRRI LLGEHRLVSV HWPASVRTIL 
       130        140        150        160        170        180 
GSGCLSNLHD SSHKQRKKVI MRAFSREALE CYVPVITEEV GSSLEQWLSC GERGLLVYPE 
       190        200        210        220        230        240 
VKRLMFRIAM RILLGCEPQL AGDGDSEQQL VEAFEEMTRN LFSLPIDVPF SGLYRGMKAR 
       250        260        270        280        290        300 
NLIHARIEQN IRAKICGLRA SEAGQGCKDA LQLLIEHSWE RGERLDMQAL KQSSTELLFG 
       310        320        330        340        350        360 
GHETTASAAT SLITYLGLYP HVLQKVREEL KSKGLLCKSN QDNKLDMEIL EQLKYIGCVI 
       370        380        390        400        410        420 
KETLRLNPPV PGGFRVALKT FELNGYQIPK GWNVIYSICD THDVAEIFTN KEEFNPDRFM 
       430        440        450        460        470        480 
LPHPEDASRF SFIPFGGGLR SCVGKEFAKI LLKIFTVELA RHCDWQLLNG PPTMKTSPTV 
       490    
YPVDNLPARF THFHGEI



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O43174-1-unknown MGLPAL... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    O43174-70-unknown MKRRKY... 70 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt71512

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...FHGEI 497 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...FHGEI 497 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt67130

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)