O43196: MutS protein homolog 5

General Information

Protein names	- MutS protein homolog 5 - hMSH5
Gene names	MSH5
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O43196

2 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of MutS protein homolog 5 - Isoform 3 of MutS protein homolog 5 - Isoform 4 of MutS protein homolog 5

Sequence View

        10         20         30         40         50         60
MASLGANPRR TPQGPRPGAA SSGFPSPAPV PGPREAEEEE VEEEEELAEI HLCVLWNSGY
        70         80         90        100        110        120
LGIAYYDTSD STIHFMPDAP DHESLKLLQR VLDEINPQSV VTSAKQDENM TRFLGKLASQ
       130        140        150        160        170        180
EHREPKRPEI IFLPSVDFGL EISKQRLLSG NYSFIPDAMT ATEKILFLSS IIPFDCLLTV
       190        200        210        220        230        240
RALGGLLKFL GRRRIGVELE DYNVSVPILG FKKFMLTHLV NIDQDTYSVL QIFKSESHPS
       250        260        270        280        290        300
VYKVASGLKE GLSLFGILNR CHCKWGEKLL RLWFTRPTHD LGELSSRLDV IQFFLLPQNL
       310        320        330        340        350        360
DMAQMLHRLL GHIKNVPLIL KRMKLSHTKV SDWQVLYKTV YSALGLRDAC RSLPQSIQLF
       370        380        390        400        410        420
RDIAQEFSDD LHHIASLIGK VVDFEGSLAE NRFTVLPNID PEIDEKKRRL MGLPSFLTEV
       430        440        450        460        470        480
ARKELENLDS RIPSCSVIYI PLIGFLLSIP RLPSMVEASD FEINGLDFMF LSEEKLHYRS
       490        500        510        520        530        540
ARTKELDALL GDLHCEIRDQ ETLLMYQLQC QVLARAAVLT RVLDLASRLD VLLALASAAR
       550        560        570        580        590        600
DYGYSRPRYS PQVLGVRIQN GRHPLMELCA RTFVPNSTEC GGDKGRVKVI TGPNSSGKSI
       610        620        630        640        650        660
YLKQVGLITF MALVGSFVPA EEAEIGAVDA IFTRIHSCES ISLGLSTFMI DLNQVAKAVN
       670        680        690        700        710        720
NATAQSLVLI DEFGKGTNTV DGLALLAAVL RHWLARGPTC PHIFVATNFL SLVQLQLLPQ
       730        740        750        760        770        780
GPLVQYLTME TCEDGNDLVF FYQVCEGVAK ASHASHTAAQ AGLPDKLVAR GKEVSDLIRS
       790        800        810        820        830
GKPIKPVKDL LKKNQMENCQ TLVDKFMKLD LEDPNLDLNV FMSQEVLPAA TSIL         10         20         30         40         50         60
MASLGANPRR TPQGPRPGAA SSGFPSPAPV PGPREAEEEE VEEEEELAEI HLCVLWNSGY
        70         80         90        100        110        120
LGIAYYDTSD STIHFMPDAP DHESLKLLQR VLDEINPQSV VTSAKQDENM TRFLGKLASQ
       130        140        150        160        170        180
EHREPKRPEI IFLPSVDFGL EISKQRLLSG NYSFIPDAMT ATEKILFLSS IIPFDCLLTV
       190        200        210        220        230        240
RALGGLLKFL GRRRIGVELE DYNVSVPILG FKKFMLTHLV NIDQDTYSVL QIFKSESHPS
       250        260        270        280        290        300
VYKVASGLKE GLSLFGILNR CHCKWGEKLL RLWFTRPTHD LGELSSRLDV IQFFLLPQNL
       310        320        330        340        350        360
DMAQMLHRLL GHIKNVPLIL KRMKLSHTKV SDWQVLYKTV YSALGLRDAC RSLPQSIQLF
       370        380        390        400        410        420
RDIAQEFSDD LHHIASLIGK VVDFEGSLAE NRFTVLPNID PEIDEKKRRL MGLPSFLTEV
       430        440        450        460        470        480
ARKELENLDS RIPSCSVIYI PLIGFLLSIP RLPSMVEASD FEINGLDFMF LSEEKLHYRS
       490        500        510        520        530        540
ARTKELDALL GDLHCEIRDQ ETLLMYQLQC QVLARAAVLT RVLDLASRLD VLLALASAAR
       550        560        570        580        590        600
DYGYSRPRYS PQVLGVRIQN GRHPLMELCA RTFVPNSTEC GGDKGRVKVI TGPNSSGKSI
       610        620        630        640        650        660
YLKQVGLITF MALVGSFVPA EEAEIGAVDA IFTRIHSCES ISLGLSTFMI DLNQVAKAVN
       670        680        690        700        710        720
NATAQSLVLI DEFGKGTNTV DGLALLAAVL RHWLARGPTC PHIFVATNFL SLVQLQLLPQ
       730        740        750        760        770        780
GPLVQYLTME TCEDGNDLVF FYQVCEGVAK ASHASHTAAQ AGLPDKLVAR GKEVSDLIRS
       790        800        810        820        830
GKPIKPVKDL LKKNQMENCQ TLVDKFMKLD LEDPNLDLNV FMSQEVLPAA TSIL         10         20         30         40         50         60
MASLGANPRR TPQGPRPGAA SSGFPSPAPV PGPREAEEEE VEEEEELAEI HLCVLWNSGY
        70         80         90        100        110        120
LGIAYYDTSD STIHFMPDAP DHESLKLLQR VLDEINPQSV VTSAKQDENM TRFLGKLASQ
       130        140        150        160        170        180
EHREPKRPEI IFLPSVDFGL EISKQRLLSG NYSFIPDAMT ATEKILFLSS IIPFDCLLTV
       190        200        210        220        230        240
RALGGLLKFL GRRRIGVELE DYNVSVPILG FKKFMLTHLV NIDQDTYSVL QIFKSESHPS
       250        260        270        280        290        300
VYKVASGLKE GLSLFGILNR CHCKWGEKLL RLWFTRPTHD LGELSSRLDV IQFFLLPQNL
       310        320        330        340        350        360
DMAQMLHRLL GHIKNVPLIL KRMKLSHTKV SDWQVLYKTV YSALGLRDAC RSLPQSIQLF
       370        380        390        400        410        420
RDIAQEFSDD LHHIASLIGK VVDFEGSLAE NRFTVLPNID PEIDEKKRRL MGLPSFLTEV
       430        440        450        460        470        480
ARKELENLDS RIPSCSVIYI PLIGFLLSIP RLPSMVEASD FEINGLDFMF LSEEKLHYRS
       490        500        510        520        530        540
ARTKELDALL GDLHCEIRDQ ETLLMYQLQC QVLARAAVLT RVLDLASRLD VLLALASAAR
       550        560        570        580        590        600
DYGYSRPRYS PQVLGVRIQN GRHPLMELCA RTFVPNSTEC GGDKGRVKVI TGPNSSGKSI
       610        620        630        640        650        660
YLKQVGLITF MALVGSFVPA EEAEIGAVDA IFTRIHSCES ISLGLSTFMI DLNQVAKAVN
       670        680        690        700        710        720
NATAQSLVLI DEFGKGTNTV DGLALLAAVL RHWLARGPTC PHIFVATNFL SLVQLQLLPQ
       730        740        750        760        770        780
GPLVQYLTME TCEDGNDLVF FYQVCEGVAK ASHASHTAAQ AGLPDKLVAR GKEVSDLIRS
       790        800        810        820        830
GKPIKPVKDL LKKNQMENCQ TLVDKFMKLD LEDPNLDLNV FMSQEVLPAA TSIL

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
O43196-1-unknown	MASLGA...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O43196-1-unknown	MASLGA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt81606
O43196-1-unknown	MASLGA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt81607
O43196-1-unknown	MASLGA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt81608
O43196-164-unknown	KILFLS...	164	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000397355
O43196-164-unknown	KILFLS...	164	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt197748

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LGRRRI	194	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000391401
...LGRRRI	194	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155550
...GEKLLR	270	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000396509
...GEKLLR	270	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000404892
...GEKLLR	270	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000400187
...GEKLLR	270	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000415811
...GEKLLR	270	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000397355
...ATSIL	834	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...ATSIL	834	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt77226
...ATSIL	834	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt77224
...ATSIL	834	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt77225

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)