O43236: Septin-4

General Information

Protein names	- Septin-4 - Apoptosis-related protein in the TGF-beta signaling pathway - ARTS - Bradeion beta - Brain protein H5 - CE5B3 beta - Cell division control-related protein 2 - hCDCREL-2 - Cerebral protein 7 - Peanut-like protein 2
Gene names	SEPT4
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O43236

2 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Septin-4 - Isoform 3 of Septin-4 - Isoform 4 of Septin-4 - Isoform 5 of Septin-4 - Isoform ARTS of Septin-4

Sequence View

        10         20         30         40         50         60
MDRSLGWQGN SVPEDRTEAG IKRFLEDTTD DGELSKFVKD FSGNASCHPP EAKTWASRPQ
        70         80         90        100        110        120
VPEPRPQAPD LYDDDLEFRP PSRPQSSDNQ QYFCAPAPLS PSARPRSPWG KLDPYDSSED
       130        140        150        160        170        180
DKEYVGFATL PNQVHRKSVK KGFDFTLMVA GESGLGKSTL VNSLFLTDLY RDRKLLGAEE
       190        200        210        220        230        240
RIMQTVEITK HAVDIEEKGV RLRLTIVDTP GFGDAVNNTE CWKPVAEYID QQFEQYFRDE
       250        260        270        280        290        300
SGLNRKNIQD NRVHCCLYFI SPFGHGLRPL DVEFMKALHQ RVNIVPILAK ADTLTPPEVD
       310        320        330        340        350        360
HKKRKIREEI EHFGIKIYQF PDCDSDEDED FKLQDQALKE SIPFAVIGSN TVVEARGRRV
       370        380        390        400        410        420
RGRLYPWGIV EVENPGHCDF VKLRTMLVRT HMQDLKDVTR ETHYENYRAQ CIQSMTRLVV
       430        440        450        460        470
KERNRNKLTR ESGTDFPIPA VPPGTDPETE KLIREKDEEL RRMQEMLHKI QKQMKENY         10         20         30         40         50         60
MDRSLGWQGN SVPEDRTEAG IKRFLEDTTD DGELSKFVKD FSGNASCHPP EAKTWASRPQ
        70         80         90        100        110        120
VPEPRPQAPD LYDDDLEFRP PSRPQSSDNQ QYFCAPAPLS PSARPRSPWG KLDPYDSSED
       130        140        150        160        170        180
DKEYVGFATL PNQVHRKSVK KGFDFTLMVA GESGLGKSTL VNSLFLTDLY RDRKLLGAEE
       190        200        210        220        230        240
RIMQTVEITK HAVDIEEKGV RLRLTIVDTP GFGDAVNNTE CWKPVAEYID QQFEQYFRDE
       250        260        270        280        290        300
SGLNRKNIQD NRVHCCLYFI SPFGHGLRPL DVEFMKALHQ RVNIVPILAK ADTLTPPEVD
       310        320        330        340        350        360
HKKRKIREEI EHFGIKIYQF PDCDSDEDED FKLQDQALKE SIPFAVIGSN TVVEARGRRV
       370        380        390        400        410        420
RGRLYPWGIV EVENPGHCDF VKLRTMLVRT HMQDLKDVTR ETHYENYRAQ CIQSMTRLVV
       430        440        450        460        470
KERNRNKLTR ESGTDFPIPA VPPGTDPETE KLIREKDEEL RRMQEMLHKI QKQMKENY         10         20         30         40         50         60
MDRSLGWQGN SVPEDRTEAG IKRFLEDTTD DGELSKFVKD FSGNASCHPP EAKTWASRPQ
        70         80         90        100        110        120
VPEPRPQAPD LYDDDLEFRP PSRPQSSDNQ QYFCAPAPLS PSARPRSPWG KLDPYDSSED
       130        140        150        160        170        180
DKEYVGFATL PNQVHRKSVK KGFDFTLMVA GESGLGKSTL VNSLFLTDLY RDRKLLGAEE
       190        200        210        220        230        240
RIMQTVEITK HAVDIEEKGV RLRLTIVDTP GFGDAVNNTE CWKPVAEYID QQFEQYFRDE
       250        260        270        280        290        300
SGLNRKNIQD NRVHCCLYFI SPFGHGLRPL DVEFMKALHQ RVNIVPILAK ADTLTPPEVD
       310        320        330        340        350        360
HKKRKIREEI EHFGIKIYQF PDCDSDEDED FKLQDQALKE SIPFAVIGSN TVVEARGRRV
       370        380        390        400        410        420
RGRLYPWGIV EVENPGHCDF VKLRTMLVRT HMQDLKDVTR ETHYENYRAQ CIQSMTRLVV
       430        440        450        460        470
KERNRNKLTR ESGTDFPIPA VPPGTDPETE KLIREKDEEL RRMQEMLHKI QKQMKENY         10         20         30         40         50         60
MDRSLGWQGN SVPEDRTEAG IKRFLEDTTD DGELSKFVKD FSGNASCHPP EAKTWASRPQ
        70         80         90        100        110        120
VPEPRPQAPD LYDDDLEFRP PSRPQSSDNQ QYFCAPAPLS PSARPRSPWG KLDPYDSSED
       130        140        150        160        170        180
DKEYVGFATL PNQVHRKSVK KGFDFTLMVA GESGLGKSTL VNSLFLTDLY RDRKLLGAEE
       190        200        210        220        230        240
RIMQTVEITK HAVDIEEKGV RLRLTIVDTP GFGDAVNNTE CWKPVAEYID QQFEQYFRDE
       250        260        270        280        290        300
SGLNRKNIQD NRVHCCLYFI SPFGHGLRPL DVEFMKALHQ RVNIVPILAK ADTLTPPEVD
       310        320        330        340        350        360
HKKRKIREEI EHFGIKIYQF PDCDSDEDED FKLQDQALKE SIPFAVIGSN TVVEARGRRV
       370        380        390        400        410        420
RGRLYPWGIV EVENPGHCDF VKLRTMLVRT HMQDLKDVTR ETHYENYRAQ CIQSMTRLVV
       430        440        450        460        470
KERNRNKLTR ESGTDFPIPA VPPGTDPETE KLIREKDEEL RRMQEMLHKI QKQMKENY         10         20         30         40         50         60
MDRSLGWQGN SVPEDRTEAG IKRFLEDTTD DGELSKFVKD FSGNASCHPP EAKTWASRPQ
        70         80         90        100        110        120
VPEPRPQAPD LYDDDLEFRP PSRPQSSDNQ QYFCAPAPLS PSARPRSPWG KLDPYDSSED
       130        140        150        160        170        180
DKEYVGFATL PNQVHRKSVK KGFDFTLMVA GESGLGKSTL VNSLFLTDLY RDRKLLGAEE
       190        200        210        220        230        240
RIMQTVEITK HAVDIEEKGV RLRLTIVDTP GFGDAVNNTE CWKPVAEYID QQFEQYFRDE
       250        260        270        280        290        300
SGLNRKNIQD NRVHCCLYFI SPFGHGLRPL DVEFMKALHQ RVNIVPILAK ADTLTPPEVD
       310        320        330        340        350        360
HKKRKIREEI EHFGIKIYQF PDCDSDEDED FKLQDQALKE SIPFAVIGSN TVVEARGRRV
       370        380        390        400        410        420
RGRLYPWGIV EVENPGHCDF VKLRTMLVRT HMQDLKDVTR ETHYENYRAQ CIQSMTRLVV
       430        440        450        460        470
KERNRNKLTR ESGTDFPIPA VPPGTDPETE KLIREKDEEL RRMQEMLHKI QKQMKENY

Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
O43236-1-unknown	MDRSLG...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O43236-148-unknown	MVAGES...	148	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt89284
O43236-148-unknown	MVAGES...	148	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt106883
O43236-148-unknown	MVAGES...	148	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt106886
O43236-148-unknown	MVAGES...	148	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt106885
O43236-148-unknown	MVAGES...	148	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt106884

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...MKENY	478	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...MKENY	478	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt84902
...MKENY	478	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt84899
...MKENY	478	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt84900
...MKENY	478	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt84901

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

TopFIND

O43236: Septin-4

General Information

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates