O43237: Cytoplasmic dynein 1 light intermediate chain 2

General Information

Protein names	- Cytoplasmic dynein 1 light intermediate chain 2 - Dynein light intermediate chain 2, cytosolic - LIC-2 - LIC53/55
Gene names	DYNC1LI2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O43237

3 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAPVGVEKKL LLGPNGPAVA AAGDLTSEEE EGQSLWSSIL SEVSTRARSK LPSGKNILVF
        70         80         90        100        110        120
GEDGSGKTTL MTKLQGAEHG KKGRGLEYLY LSVHDEDRDD HTRCNVWILD GDLYHKGLLK
       130        140        150        160        170        180
FAVSAESLPE TLVIFVADMS RPWTVMESLQ KWASVLREHI DKMKIPPEKM RELERKFVKD
       190        200        210        220        230        240
FQDYMEPEEG CQGSPQRRGP LTSGSDEENV ALPLGDNVLT HNLGIPVLVV CTKCDAVSVL
       250        260        270        280        290        300
EKEHDYRDEH LDFIQSHLRR FCLQYGAALI YTSVKEEKNL DLLYKYIVHK TYGFHFTTPA
       310        320        330        340        350        360
LVVEKDAVFI PAGWDNEKKI AILHENFTTV KPEDAYEDFI VKPPVRKLVH DKELAAEDEQ
       370        380        390        400        410        420
VFLMKQQSLL AKQPATPTRA SESPARGPSG SPRTQGRGGP ASVPSSSPGT SVKKPDPNIK
       430        440        450        460        470        480
NNAASEGVLA SFFNSLLSKK TGSPGSPGAG GVQSTAKKSG QKTVLSNVQE ELDRMTRKPD
       490
SMVTNSSTEN EA

Isoforms

- Isoform 2 of Cytoplasmic dynein 1 light intermediate chain 2

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
O43237-1-unknown	MAPVGV...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O43237-1-unknown	MAPVGV...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt72400
O43237-312-unknown	AGWDNE...	312	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000462017
O43237-312-unknown	AGWDNE...	312	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt132128
O43237-348-unknown	LVHDKE...	348	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000462434
O43237-348-unknown	LVHDKE...	348	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt132126

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...THNLGI	224	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000457707
...THNLGI	224	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt113138
...TENEA	492		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...TENEA	492		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...TENEA	492	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...TENEA	492	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt68018
...TENEA	492		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...TENEA	492		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)