TopFIND 4.0

O43280: Trehalase {ECO:0000303|PubMed:9427547}

General Information

Protein names
- Trehalase {ECO:0000303|PubMed:9427547}
- 3.2.1.28 {ECO:0000269|PubMed:8773341, ECO:0000269|PubMed:9427547}
- Alpha,alpha-trehalase
- Alpha,alpha-trehalose glucohydrolase
Gene names TREH
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID O43280

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MPGRTWELCL LLLLGLGLGS QEALPPPCES EIYCHGELLN QVQMAKLYQD DKQFVDMPLS 
        70         80         90        100        110        120 
IAPEQVLQTF TELSRDHNHS IPREQLQAFV HEHFQAKGQE LQPWTPADWK DSPQFLQKIS 
       130        140        150        160        170        180 
DAKLRAWAGQ LHQLWKKLGK KMKPEVLSHP ERFSLIYSEH PFIVPGGRFV EFYYWDSYWV 
       190        200        210        220        230        240 
MEGLLLSEMA ETVKGMLQNF LDLVKTYGHV PNGGRVYYLQ RSQPPLLTLM MDCYLTHTND 
       250        260        270        280        290        300 
TAFLQENIET LALELDFWTK NRTVSVSLEG KNYLLNRYYV PYGGPRPESY SKDVELADTL 
       310        320        330        340        350        360 
PEGDREALWA ELKAGAESGW DFSSRWLIGG PNPNSLSGIR TSKLVPVDLN AFLCQAEELM 
       370        380        390        400        410        420 
SNFYSRLGND SQATKYRILR SQRLAALNTV LWDEQTGAWF DYDLEKKKKN REFYPSNLTP 
       430        440        450        460        470        480 
LWAGCFSDPG VADKALKYLE DNRILTYQYG IPTSLQKTGQ QWDFPNAWAP LQDLVIRGLA 
       490        500        510        520        530        540 
KAPLRRAQEV AFQLAQNWIR TNFDVYSQKS AMYEKYDVSN GGQPGGGGEY EVQEGFGWTN 
       550        560        570        580    
GVVLMLLDRY GDRLTSGAKL AFLEPHCLAA TLLPSLLLSL LPW

Isoforms

- Isoform 2 of Trehalase

Sequence View

        10         20         30         40         50         60 
MPGRTWELCL LLLLGLGLGS QEALPPPCES EIYCHGELLN QVQMAKLYQD DKQFVDMPLS 
        70         80         90        100        110        120 
IAPEQVLQTF TELSRDHNHS IPREQLQAFV HEHFQAKGQE LQPWTPADWK DSPQFLQKIS 
       130        140        150        160        170        180 
DAKLRAWAGQ LHQLWKKLGK KMKPEVLSHP ERFSLIYSEH PFIVPGGRFV EFYYWDSYWV 
       190        200        210        220        230        240 
MEGLLLSEMA ETVKGMLQNF LDLVKTYGHV PNGGRVYYLQ RSQPPLLTLM MDCYLTHTND 
       250        260        270        280        290        300 
TAFLQENIET LALELDFWTK NRTVSVSLEG KNYLLNRYYV PYGGPRPESY SKDVELADTL 
       310        320        330        340        350        360 
PEGDREALWA ELKAGAESGW DFSSRWLIGG PNPNSLSGIR TSKLVPVDLN AFLCQAEELM 
       370        380        390        400        410        420 
SNFYSRLGND SQATKYRILR SQRLAALNTV LWDEQTGAWF DYDLEKKKKN REFYPSNLTP 
       430        440        450        460        470        480 
LWAGCFSDPG VADKALKYLE DNRILTYQYG IPTSLQKTGQ QWDFPNAWAP LQDLVIRGLA 
       490        500        510        520        530        540 
KAPLRRAQEV AFQLAQNWIR TNFDVYSQKS AMYEKYDVSN GGQPGGGGEY EVQEGFGWTN 
       550        560        570        580    
GVVLMLLDRY GDRLTSGAKL AFLEPHCLAA TLLPSLLLSL LPW



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O43280-1-unknown MPGRTW... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt92967
    O43280-24-unknown LPPPCE... 24 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    O43280-24-unknown LPPPCE... 24 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt113488

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)