TopFIND 4.0

O43493: Trans-Golgi network integral membrane protein 2

General Information

Protein names
- Trans-Golgi network integral membrane protein 2
- TGN38 homolog
- TGN46
- TGN48
- Trans-Golgi network protein TGN51
Gene names TGOLN2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID O43493

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MRFVVALVLL NVAAAGAVPL LATESVKQEE AGVRPSAGNV STHPSLSQRP GGSTKSHPEP 
        70         80         90        100        110        120 
QTPKDSPSKS SAEAQTPEDT PNKSGAEAKT QKDSSNKSGA EAKTQKGSTS KSGSEAQTTK 
       130        140        150        160        170        180 
DSTSKSHPEL QTPKDSTGKS GAEAQTPEDS PNRSGAEAKT QKDSPSKSGS EAQTTKDVPN 
       190        200        210        220        230        240 
KSGADGQTPK DGSSKSGAED QTPKDVPNKS GAEKQTPKDG SNKSGAEEQG PIDGPSKSGA 
       250        260        270        280        290        300 
EEQTSKDSPN KVVPEQPSRK DHSKPISNPS DNKELPKADT NQLADKGKLS PHAFKTESGE 
       310        320        330        340        350        360 
ETDLISPPQE EVKSSEPTED VEPKEAEDDD TGPEEGSPPK EEKEKMSGSA SSENREGTLS 
       370        380        390        400        410        420 
DSTGSEKDDL YPNGSGNGSA ESSHFFAYLV TAAILVAVLY IAHHNKRKII AFVLEGKRSK 
       430        440        450        460        470    
VTRRPKASDY QRLDQKYVLI LNVFPAPPKR SFFPVLTEWY IPLEKDERHQ WIVLLSFQL

Isoforms

- Isoform TGN46 of Trans-Golgi network integral membrane protein 2 - Isoform TGN48 of Trans-Golgi network integral membrane protein 2 - Isoform 4 of Trans-Golgi network integral membrane protein 2 - Isoform 5 of Trans-Golgi network integral membrane protein 2 - Isoform 6 of Trans-Golgi network integral membrane protein 2

Sequence View

        10         20         30         40         50         60 
MRFVVALVLL NVAAAGAVPL LATESVKQEE AGVRPSAGNV STHPSLSQRP GGSTKSHPEP 
        70         80         90        100        110        120 
QTPKDSPSKS SAEAQTPEDT PNKSGAEAKT QKDSSNKSGA EAKTQKGSTS KSGSEAQTTK 
       130        140        150        160        170        180 
DSTSKSHPEL QTPKDSTGKS GAEAQTPEDS PNRSGAEAKT QKDSPSKSGS EAQTTKDVPN 
       190        200        210        220        230        240 
KSGADGQTPK DGSSKSGAED QTPKDVPNKS GAEKQTPKDG SNKSGAEEQG PIDGPSKSGA 
       250        260        270        280        290        300 
EEQTSKDSPN KVVPEQPSRK DHSKPISNPS DNKELPKADT NQLADKGKLS PHAFKTESGE 
       310        320        330        340        350        360 
ETDLISPPQE EVKSSEPTED VEPKEAEDDD TGPEEGSPPK EEKEKMSGSA SSENREGTLS 
       370        380        390        400        410        420 
DSTGSEKDDL YPNGSGNGSA ESSHFFAYLV TAAILVAVLY IAHHNKRKII AFVLEGKRSK 
       430        440        450        460        470    
VTRRPKASDY QRLDQKYVLI LNVFPAPPKR SFFPVLTEWY IPLEKDERHQ WIVLLSFQL         10         20         30         40         50         60 
MRFVVALVLL NVAAAGAVPL LATESVKQEE AGVRPSAGNV STHPSLSQRP GGSTKSHPEP 
        70         80         90        100        110        120 
QTPKDSPSKS SAEAQTPEDT PNKSGAEAKT QKDSSNKSGA EAKTQKGSTS KSGSEAQTTK 
       130        140        150        160        170        180 
DSTSKSHPEL QTPKDSTGKS GAEAQTPEDS PNRSGAEAKT QKDSPSKSGS EAQTTKDVPN 
       190        200        210        220        230        240 
KSGADGQTPK DGSSKSGAED QTPKDVPNKS GAEKQTPKDG SNKSGAEEQG PIDGPSKSGA 
       250        260        270        280        290        300 
EEQTSKDSPN KVVPEQPSRK DHSKPISNPS DNKELPKADT NQLADKGKLS PHAFKTESGE 
       310        320        330        340        350        360 
ETDLISPPQE EVKSSEPTED VEPKEAEDDD TGPEEGSPPK EEKEKMSGSA SSENREGTLS 
       370        380        390        400        410        420 
DSTGSEKDDL YPNGSGNGSA ESSHFFAYLV TAAILVAVLY IAHHNKRKII AFVLEGKRSK 
       430        440        450        460        470    
VTRRPKASDY QRLDQKYVLI LNVFPAPPKR SFFPVLTEWY IPLEKDERHQ WIVLLSFQL         10         20         30         40         50         60 
MRFVVALVLL NVAAAGAVPL LATESVKQEE AGVRPSAGNV STHPSLSQRP GGSTKSHPEP 
        70         80         90        100        110        120 
QTPKDSPSKS SAEAQTPEDT PNKSGAEAKT QKDSSNKSGA EAKTQKGSTS KSGSEAQTTK 
       130        140        150        160        170        180 
DSTSKSHPEL QTPKDSTGKS GAEAQTPEDS PNRSGAEAKT QKDSPSKSGS EAQTTKDVPN 
       190        200        210        220        230        240 
KSGADGQTPK DGSSKSGAED QTPKDVPNKS GAEKQTPKDG SNKSGAEEQG PIDGPSKSGA 
       250        260        270        280        290        300 
EEQTSKDSPN KVVPEQPSRK DHSKPISNPS DNKELPKADT NQLADKGKLS PHAFKTESGE 
       310        320        330        340        350        360 
ETDLISPPQE EVKSSEPTED VEPKEAEDDD TGPEEGSPPK EEKEKMSGSA SSENREGTLS 
       370        380        390        400        410        420 
DSTGSEKDDL YPNGSGNGSA ESSHFFAYLV TAAILVAVLY IAHHNKRKII AFVLEGKRSK 
       430        440        450        460        470    
VTRRPKASDY QRLDQKYVLI LNVFPAPPKR SFFPVLTEWY IPLEKDERHQ WIVLLSFQL         10         20         30         40         50         60 
MRFVVALVLL NVAAAGAVPL LATESVKQEE AGVRPSAGNV STHPSLSQRP GGSTKSHPEP 
        70         80         90        100        110        120 
QTPKDSPSKS SAEAQTPEDT PNKSGAEAKT QKDSSNKSGA EAKTQKGSTS KSGSEAQTTK 
       130        140        150        160        170        180 
DSTSKSHPEL QTPKDSTGKS GAEAQTPEDS PNRSGAEAKT QKDSPSKSGS EAQTTKDVPN 
       190        200        210        220        230        240 
KSGADGQTPK DGSSKSGAED QTPKDVPNKS GAEKQTPKDG SNKSGAEEQG PIDGPSKSGA 
       250        260        270        280        290        300 
EEQTSKDSPN KVVPEQPSRK DHSKPISNPS DNKELPKADT NQLADKGKLS PHAFKTESGE 
       310        320        330        340        350        360 
ETDLISPPQE EVKSSEPTED VEPKEAEDDD TGPEEGSPPK EEKEKMSGSA SSENREGTLS 
       370        380        390        400        410        420 
DSTGSEKDDL YPNGSGNGSA ESSHFFAYLV TAAILVAVLY IAHHNKRKII AFVLEGKRSK 
       430        440        450        460        470    
VTRRPKASDY QRLDQKYVLI LNVFPAPPKR SFFPVLTEWY IPLEKDERHQ WIVLLSFQL         10         20         30         40         50         60 
MRFVVALVLL NVAAAGAVPL LATESVKQEE AGVRPSAGNV STHPSLSQRP GGSTKSHPEP 
        70         80         90        100        110        120 
QTPKDSPSKS SAEAQTPEDT PNKSGAEAKT QKDSSNKSGA EAKTQKGSTS KSGSEAQTTK 
       130        140        150        160        170        180 
DSTSKSHPEL QTPKDSTGKS GAEAQTPEDS PNRSGAEAKT QKDSPSKSGS EAQTTKDVPN 
       190        200        210        220        230        240 
KSGADGQTPK DGSSKSGAED QTPKDVPNKS GAEKQTPKDG SNKSGAEEQG PIDGPSKSGA 
       250        260        270        280        290        300 
EEQTSKDSPN KVVPEQPSRK DHSKPISNPS DNKELPKADT NQLADKGKLS PHAFKTESGE 
       310        320        330        340        350        360 
ETDLISPPQE EVKSSEPTED VEPKEAEDDD TGPEEGSPPK EEKEKMSGSA SSENREGTLS 
       370        380        390        400        410        420 
DSTGSEKDDL YPNGSGNGSA ESSHFFAYLV TAAILVAVLY IAHHNKRKII AFVLEGKRSK 
       430        440        450        460        470    
VTRRPKASDY QRLDQKYVLI LNVFPAPPKR SFFPVLTEWY IPLEKDERHQ WIVLLSFQL



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...SFQL 480 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)