O43663: Protein regulator of cytokinesis 1 {ECO:0000312|HGNC:HGNC:9341}

General Information

Protein names	- Protein regulator of cytokinesis 1 {ECO:0000312\|HGNC:HGNC:9341}
Gene names	PRC1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O43663

2 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Protein regulator of cytokinesis 1 - Isoform 3 of Protein regulator of cytokinesis 1 - Isoform 4 of Protein regulator of cytokinesis 1

Sequence View

        10         20         30         40         50         60
MRRSEVLAEE SIVCLQKALN HLREIWELIG IPEDQRLQRT EVVKKHIKEL LDMMIAEEES
        70         80         90        100        110        120
LKERLIKSIS VCQKELNTLC SELHVEPFQE EGETTILQLE KDLRTQVELM RKQKKERKQE
       130        140        150        160        170        180
LKLLQEQDQE LCEILCMPHY DIDSASVPSL EELNQFRQHV TTLRETKASR REEFVSIKRQ
       190        200        210        220        230        240
IILCMEALDH TPDTSFERDV VCEDEDAFCL SLENIATLQK LLRQLEMQKS QNEAVCEGLR
       250        260        270        280        290        300
TQIRELWDRL QIPEEEREAV ATIMSGSKAK VRKALQLEVD RLEELKMQNM KKVIEAIRVE
       310        320        330        340        350        360
LVQYWDQCFY SQEQRQAFAP FCAEDYTESL LQLHDAEIVR LKNYYEVHKE LFEGVQKWEE
       370        380        390        400        410        420
TWRLFLEFER KASDPNRFTN RGGNLLKEEK QRAKLQKMLP KLEEELKARI ELWEQEHSKA
       430        440        450        460        470        480
FMVNGQKFME YVAEQWEMHR LEKERAKQER QLKNKKQTET EMLYGSAPRT PSKRRGLAPN
       490        500        510        520        530        540
TPGKARKLNT TTMSNATANS SIRPIFGGTV YHSPVSRLPP SGSKPVAAST CSGKKTPRTG
       550        560        570        580        590        600
RHGANKENLE LNGSILSGGY PGSAPLQRNF SINSVASTYS EFAKDPSLSD SSTVGLQREL
       610        620
SKASKSDATS GILNSTNIQS         10         20         30         40         50         60
MRRSEVLAEE SIVCLQKALN HLREIWELIG IPEDQRLQRT EVVKKHIKEL LDMMIAEEES
        70         80         90        100        110        120
LKERLIKSIS VCQKELNTLC SELHVEPFQE EGETTILQLE KDLRTQVELM RKQKKERKQE
       130        140        150        160        170        180
LKLLQEQDQE LCEILCMPHY DIDSASVPSL EELNQFRQHV TTLRETKASR REEFVSIKRQ
       190        200        210        220        230        240
IILCMEALDH TPDTSFERDV VCEDEDAFCL SLENIATLQK LLRQLEMQKS QNEAVCEGLR
       250        260        270        280        290        300
TQIRELWDRL QIPEEEREAV ATIMSGSKAK VRKALQLEVD RLEELKMQNM KKVIEAIRVE
       310        320        330        340        350        360
LVQYWDQCFY SQEQRQAFAP FCAEDYTESL LQLHDAEIVR LKNYYEVHKE LFEGVQKWEE
       370        380        390        400        410        420
TWRLFLEFER KASDPNRFTN RGGNLLKEEK QRAKLQKMLP KLEEELKARI ELWEQEHSKA
       430        440        450        460        470        480
FMVNGQKFME YVAEQWEMHR LEKERAKQER QLKNKKQTET EMLYGSAPRT PSKRRGLAPN
       490        500        510        520        530        540
TPGKARKLNT TTMSNATANS SIRPIFGGTV YHSPVSRLPP SGSKPVAAST CSGKKTPRTG
       550        560        570        580        590        600
RHGANKENLE LNGSILSGGY PGSAPLQRNF SINSVASTYS EFAKDPSLSD SSTVGLQREL
       610        620
SKASKSDATS GILNSTNIQS         10         20         30         40         50         60
MRRSEVLAEE SIVCLQKALN HLREIWELIG IPEDQRLQRT EVVKKHIKEL LDMMIAEEES
        70         80         90        100        110        120
LKERLIKSIS VCQKELNTLC SELHVEPFQE EGETTILQLE KDLRTQVELM RKQKKERKQE
       130        140        150        160        170        180
LKLLQEQDQE LCEILCMPHY DIDSASVPSL EELNQFRQHV TTLRETKASR REEFVSIKRQ
       190        200        210        220        230        240
IILCMEALDH TPDTSFERDV VCEDEDAFCL SLENIATLQK LLRQLEMQKS QNEAVCEGLR
       250        260        270        280        290        300
TQIRELWDRL QIPEEEREAV ATIMSGSKAK VRKALQLEVD RLEELKMQNM KKVIEAIRVE
       310        320        330        340        350        360
LVQYWDQCFY SQEQRQAFAP FCAEDYTESL LQLHDAEIVR LKNYYEVHKE LFEGVQKWEE
       370        380        390        400        410        420
TWRLFLEFER KASDPNRFTN RGGNLLKEEK QRAKLQKMLP KLEEELKARI ELWEQEHSKA
       430        440        450        460        470        480
FMVNGQKFME YVAEQWEMHR LEKERAKQER QLKNKKQTET EMLYGSAPRT PSKRRGLAPN
       490        500        510        520        530        540
TPGKARKLNT TTMSNATANS SIRPIFGGTV YHSPVSRLPP SGSKPVAAST CSGKKTPRTG
       550        560        570        580        590        600
RHGANKENLE LNGSILSGGY PGSAPLQRNF SINSVASTYS EFAKDPSLSD SSTVGLQREL
       610        620
SKASKSDATS GILNSTNIQS

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
O43663-1-unknown	MRRSEV...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O43663-1-unknown	MRRSEV...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt86089
O43663-1-unknown	MRRSEV...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt86090
O43663-1-unknown	MRRSEV...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt86091
O43663-517-unknown	RLPPSG...	517	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000456737
O43663-517-unknown	RLPPSG...	517	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt132453
O43663-517-unknown	RLPPSG...	517	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt132452
O43663-517-unknown	RLPPSG...	517	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt132454

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TPDTSF	195	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000453455
...TPDTSF	195	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt114007
...TPDTSF	195	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt114006
...TPDTSF	195	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt114008
...TNIQS	620	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...TNIQS	620	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt81707
...TNIQS	620	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt81709

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)