TopFIND 4.0

O43709: Probable 18S rRNA (guanine-N(7))-methyltransferase {ECO:0000305}

General Information

Protein names
- Probable 18S rRNA (guanine-N(7))-methyltransferase {ECO:0000305}
- 2.1.1.- {ECO:0000269|PubMed:25851604}
- Bud site selection protein 23 homolog
- Metastasis-related methyltransferase 1
- Williams-Beuren syndrome chromosomal region 22 protein
- rRNA methyltransferase and ribosome maturation factor {ECO:0000312|HGNC:HGNC:16405}
Gene names WBSCR22
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID O43709

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MASRGRRPEH GGPPELFYDE TEARKYVRNS RMIDIQTRMA GRALELLYLP ENKPCYLLDI 
        70         80         90        100        110        120 
GCGTGLSGSY LSDEGHYWVG LDISPAMLDE AVDREIEGDL LLGDMGQGIP FKPGTFDGCI 
       130        140        150        160        170        180 
SISAVQWLCN ANKKSENPAK RLYCFFASLF SVLVRGSRAV LQLYPENSEQ LELITTQATK 
       190        200        210        220        230        240 
AGFSGGMVVD YPNSAKAKKF YLCLFSGPST FIPEGLSENQ DEVEPRESVF TNERFPLRMS 
       250        260        270        280    
RRGMVRKSRA WVLEKKERHR RQGREVRPDT QYTGRKRKPR F

Isoforms

- Isoform 2 of Ribosome biogenesis methyltransferase WBSCR22 - Isoform 3 of Ribosome biogenesis methyltransferase WBSCR22 - Isoform 2 of Probable 18S rRNA (guanine-N(7))-methyltransferase - Isoform 3 of Probable 18S rRNA (guanine-N(7))-methyltransferase

Sequence View

        10         20         30         40         50         60 
MASRGRRPEH GGPPELFYDE TEARKYVRNS RMIDIQTRMA GRALELLYLP ENKPCYLLDI 
        70         80         90        100        110        120 
GCGTGLSGSY LSDEGHYWVG LDISPAMLDE AVDREIEGDL LLGDMGQGIP FKPGTFDGCI 
       130        140        150        160        170        180 
SISAVQWLCN ANKKSENPAK RLYCFFASLF SVLVRGSRAV LQLYPENSEQ LELITTQATK 
       190        200        210        220        230        240 
AGFSGGMVVD YPNSAKAKKF YLCLFSGPST FIPEGLSENQ DEVEPRESVF TNERFPLRMS 
       250        260        270        280    
RRGMVRKSRA WVLEKKERHR RQGREVRPDT QYTGRKRKPR F         10         20         30         40         50         60 
MASRGRRPEH GGPPELFYDE TEARKYVRNS RMIDIQTRMA GRALELLYLP ENKPCYLLDI 
        70         80         90        100        110        120 
GCGTGLSGSY LSDEGHYWVG LDISPAMLDE AVDREIEGDL LLGDMGQGIP FKPGTFDGCI 
       130        140        150        160        170        180 
SISAVQWLCN ANKKSENPAK RLYCFFASLF SVLVRGSRAV LQLYPENSEQ LELITTQATK 
       190        200        210        220        230        240 
AGFSGGMVVD YPNSAKAKKF YLCLFSGPST FIPEGLSENQ DEVEPRESVF TNERFPLRMS 
       250        260        270        280    
RRGMVRKSRA WVLEKKERHR RQGREVRPDT QYTGRKRKPR F         10         20         30         40         50         60 
MASRGRRPEH GGPPELFYDE TEARKYVRNS RMIDIQTRMA GRALELLYLP ENKPCYLLDI 
        70         80         90        100        110        120 
GCGTGLSGSY LSDEGHYWVG LDISPAMLDE AVDREIEGDL LLGDMGQGIP FKPGTFDGCI 
       130        140        150        160        170        180 
SISAVQWLCN ANKKSENPAK RLYCFFASLF SVLVRGSRAV LQLYPENSEQ LELITTQATK 
       190        200        210        220        230        240 
AGFSGGMVVD YPNSAKAKKF YLCLFSGPST FIPEGLSENQ DEVEPRESVF TNERFPLRMS 
       250        260        270        280    
RRGMVRKSRA WVLEKKERHR RQGREVRPDT QYTGRKRKPR F         10         20         30         40         50         60 
MASRGRRPEH GGPPELFYDE TEARKYVRNS RMIDIQTRMA GRALELLYLP ENKPCYLLDI 
        70         80         90        100        110        120 
GCGTGLSGSY LSDEGHYWVG LDISPAMLDE AVDREIEGDL LLGDMGQGIP FKPGTFDGCI 
       130        140        150        160        170        180 
SISAVQWLCN ANKKSENPAK RLYCFFASLF SVLVRGSRAV LQLYPENSEQ LELITTQATK 
       190        200        210        220        230        240 
AGFSGGMVVD YPNSAKAKKF YLCLFSGPST FIPEGLSENQ DEVEPRESVF TNERFPLRMS 
       250        260        270        280    
RRGMVRKSRA WVLEKKERHR RQGREVRPDT QYTGRKRKPR F



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O43709-1-unknown MASRGR... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    O43709-1-unknown MASRGR... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt94392
    O43709-1-unknown MASRGR... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt94393

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RKPRF 281 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...RKPRF 281 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt90011

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)