O43734: Adapter protein CIKS

General Information

Protein names	- Adapter protein CIKS - Connection to IKK and SAPK/JNK - Nuclear factor NF-kappa-B activator 1 - ACT1 - TRAF3-interacting protein 2
Gene names	TRAF3IP2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O43734

4 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Adapter protein CIKS - Isoform 3 of Adapter protein CIKS - Isoform 4 of Adapter protein CIKS - Isoform 5 of Adapter protein CIKS

Sequence View

        10         20         30         40         50         60
MPPQLQETRM NRSIPVEVDE SEPYPSQLLK PIPEYSPEEE SEPPAPNIRN MAPNSLSAPT
        70         80         90        100        110        120
MLHNSSGDFS QAHSTLKLAN HQRPVSRQVT CLRTQVLEDS EDSFCRRHPG LGKAFPSGCS
       130        140        150        160        170        180
AVSEPASESV VGALPAEHQF SFMEKRNQWL VSQLSAASPD TGHDSDKSDQ SLPNASADSL
       190        200        210        220        230        240
GGSQEMVQRP QPHRNRAGLD LPTIDTGYDS QPQDVLGIRQ LERPLPLTSV CYPQDLPRPL
       250        260        270        280        290        300
RSREFPQFEP QRYPACAQML PPNLSPHAPW NYHYHCPGSP DHQVPYGHDY PRAAYQQVIQ
       310        320        330        340        350        360
PALPGQPLPG ASVRGLHPVQ KVILNYPSPW DHEERPAQRD CSFPGLPRHQ DQPHHQPPNR
       370        380        390        400        410        420
AGAPGESLEC PAELRPQVPQ PPSPAAVPRP PSNPPARGTL KTSNLPEELR KVFITYSMDT
       430        440        450        460        470        480
AMEVVKFVNF LLVNGFQTAI DIFEDRIRGI DIIKWMERYL RDKTVMIIVA ISPKYKQDVE
       490        500        510        520        530        540
GAESQLDEDE HGLHTKYIHR MMQIEFIKQG SMNFRFIPVL FPNAKKEHVP TWLQNTHVYS
       550        560        570
WPKNKKNILL RLLREEEYVA PPRGPLPTLQ VVPL         10         20         30         40         50         60
MPPQLQETRM NRSIPVEVDE SEPYPSQLLK PIPEYSPEEE SEPPAPNIRN MAPNSLSAPT
        70         80         90        100        110        120
MLHNSSGDFS QAHSTLKLAN HQRPVSRQVT CLRTQVLEDS EDSFCRRHPG LGKAFPSGCS
       130        140        150        160        170        180
AVSEPASESV VGALPAEHQF SFMEKRNQWL VSQLSAASPD TGHDSDKSDQ SLPNASADSL
       190        200        210        220        230        240
GGSQEMVQRP QPHRNRAGLD LPTIDTGYDS QPQDVLGIRQ LERPLPLTSV CYPQDLPRPL
       250        260        270        280        290        300
RSREFPQFEP QRYPACAQML PPNLSPHAPW NYHYHCPGSP DHQVPYGHDY PRAAYQQVIQ
       310        320        330        340        350        360
PALPGQPLPG ASVRGLHPVQ KVILNYPSPW DHEERPAQRD CSFPGLPRHQ DQPHHQPPNR
       370        380        390        400        410        420
AGAPGESLEC PAELRPQVPQ PPSPAAVPRP PSNPPARGTL KTSNLPEELR KVFITYSMDT
       430        440        450        460        470        480
AMEVVKFVNF LLVNGFQTAI DIFEDRIRGI DIIKWMERYL RDKTVMIIVA ISPKYKQDVE
       490        500        510        520        530        540
GAESQLDEDE HGLHTKYIHR MMQIEFIKQG SMNFRFIPVL FPNAKKEHVP TWLQNTHVYS
       550        560        570
WPKNKKNILL RLLREEEYVA PPRGPLPTLQ VVPL         10         20         30         40         50         60
MPPQLQETRM NRSIPVEVDE SEPYPSQLLK PIPEYSPEEE SEPPAPNIRN MAPNSLSAPT
        70         80         90        100        110        120
MLHNSSGDFS QAHSTLKLAN HQRPVSRQVT CLRTQVLEDS EDSFCRRHPG LGKAFPSGCS
       130        140        150        160        170        180
AVSEPASESV VGALPAEHQF SFMEKRNQWL VSQLSAASPD TGHDSDKSDQ SLPNASADSL
       190        200        210        220        230        240
GGSQEMVQRP QPHRNRAGLD LPTIDTGYDS QPQDVLGIRQ LERPLPLTSV CYPQDLPRPL
       250        260        270        280        290        300
RSREFPQFEP QRYPACAQML PPNLSPHAPW NYHYHCPGSP DHQVPYGHDY PRAAYQQVIQ
       310        320        330        340        350        360
PALPGQPLPG ASVRGLHPVQ KVILNYPSPW DHEERPAQRD CSFPGLPRHQ DQPHHQPPNR
       370        380        390        400        410        420
AGAPGESLEC PAELRPQVPQ PPSPAAVPRP PSNPPARGTL KTSNLPEELR KVFITYSMDT
       430        440        450        460        470        480
AMEVVKFVNF LLVNGFQTAI DIFEDRIRGI DIIKWMERYL RDKTVMIIVA ISPKYKQDVE
       490        500        510        520        530        540
GAESQLDEDE HGLHTKYIHR MMQIEFIKQG SMNFRFIPVL FPNAKKEHVP TWLQNTHVYS
       550        560        570
WPKNKKNILL RLLREEEYVA PPRGPLPTLQ VVPL         10         20         30         40         50         60
MPPQLQETRM NRSIPVEVDE SEPYPSQLLK PIPEYSPEEE SEPPAPNIRN MAPNSLSAPT
        70         80         90        100        110        120
MLHNSSGDFS QAHSTLKLAN HQRPVSRQVT CLRTQVLEDS EDSFCRRHPG LGKAFPSGCS
       130        140        150        160        170        180
AVSEPASESV VGALPAEHQF SFMEKRNQWL VSQLSAASPD TGHDSDKSDQ SLPNASADSL
       190        200        210        220        230        240
GGSQEMVQRP QPHRNRAGLD LPTIDTGYDS QPQDVLGIRQ LERPLPLTSV CYPQDLPRPL
       250        260        270        280        290        300
RSREFPQFEP QRYPACAQML PPNLSPHAPW NYHYHCPGSP DHQVPYGHDY PRAAYQQVIQ
       310        320        330        340        350        360
PALPGQPLPG ASVRGLHPVQ KVILNYPSPW DHEERPAQRD CSFPGLPRHQ DQPHHQPPNR
       370        380        390        400        410        420
AGAPGESLEC PAELRPQVPQ PPSPAAVPRP PSNPPARGTL KTSNLPEELR KVFITYSMDT
       430        440        450        460        470        480
AMEVVKFVNF LLVNGFQTAI DIFEDRIRGI DIIKWMERYL RDKTVMIIVA ISPKYKQDVE
       490        500        510        520        530        540
GAESQLDEDE HGLHTKYIHR MMQIEFIKQG SMNFRFIPVL FPNAKKEHVP TWLQNTHVYS
       550        560        570
WPKNKKNILL RLLREEEYVA PPRGPLPTLQ VVPL

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
O43734-1-unknown	MPPQLQ...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O43734-10-unknown	MNRSIP...	10	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt70659
O43734-10-unknown	MNRSIP...	10	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt70662
O43734-422-unknown	MEVVKF...	422	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt70660
O43734-422-unknown	MEVVKF...	422	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt95964
O43734-422-unknown	MEVVKF...	422	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt95965
O43734-466-unknown	MIIVAI...	466	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt70661
O43734-466-unknown	MIIVAI...	466	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt96045
O43734-466-unknown	MIIVAI...	466	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt96044
O43734-466-unknown	MIIVAI...	466	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt96046

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...QVVPL	574	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...QVVPL	574	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt66279
...QVVPL	574	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt66278
...QVVPL	574	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt66280
...QVVPL	574	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt66277
...QVVPL	574		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...QVVPL	574		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)