O43809: Cleavage and polyadenylation specificity factor subunit 5 {ECO:0000303|PubMed:23187700}

General Information

Protein names	- Cleavage and polyadenylation specificity factor subunit 5 {ECO:0000303\|PubMed:23187700} - Cleavage and polyadenylation specificity factor 25 kDa subunit - CPSF 25 kDa subunit - Cleavage factor Im complex 25 kDa subunit {ECO:0000303\|PubMed:9659921} - CFIm25 {ECO:0000303\|PubMed:9659921} - Nucleoside diphosphate-linked moiety X motif 21 - Nudix motif 21 - Nudix hydrolase 21 {ECO:0000305} - Pre-mRNA cleavage factor Im 68 kDa subunit
Gene names	NUDT21
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O43809

3 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSVVPPNRSQ TGWPRGVTQF GNKYIQQTKP LTLERTINLY PLTNYTFGTK EPLYEKDSSV
        70         80         90        100        110        120
AARFQRMREE FDKIGMRRTV EGVLIVHEHR LPHVLLLQLG TTFFKLPGGE LNPGEDEVEG
       130        140        150        160        170        180
LKRLMTEILG RQDGVLQDWV IDDCIGNWWR PNFEPPQYPY IPAHITKPKE HKKLFLVQLQ
       190        200        210        220
EKALFAVPKN YKLVAAPLFE LYDNAPGYGP IISSLPQLLS RFNFIYN

Isoforms

Sequence View

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Physiological Relevance:

Evidence Codes:

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Biological System:

Protease Assignment Confidence:

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Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O43809-2-unknown	MSVVPP...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O43809-2-Acetylation	SVVPPN...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O43809-2-Acetylation	SVVPPN...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
O43809-2-Acetylation	SVVPPN...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
O43809-67-unknown	MREEFD...	67		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000454790
O43809-67-unknown	MREEFD...	67		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000457942

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DGVLQD	137	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000457942
...IISSLP	215	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000454790
...NFIYN	227	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)