O54834: Rho GTPase-activating protein 6

General Information

Protein names	- Rho GTPase-activating protein 6 - Rho-type GTPase-activating protein 6 - Rho-type GTPase-activating protein RhoGAPX-1
Gene names	Arhgap6
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	O54834

2 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSAQSLLHSV FSCSSPASGG TASAKGFSKR KLRQTRSLDP ALIGGCGSEM GAEGGLRGST
        70         80         90        100        110        120
VSRLHSPQLL AEGLGSRLAS SPRSQHLRAT RFQTPRPLCS SFSTPSTPQE KSPSGSFHFD
       130        140        150        160        170        180
YEVPLSRSGL KKSMAWDLPS VLAGSGSASS RSPASILSSS GGGPNGIFSS PRRWLQQRKF
       190        200        210        220        230        240
QPPPNSRSHP YVVWRSEGDF TWNSMSGRSV RLRSVPIQSL SELERARLQE VAFYQLQQDC
       250        260        270        280        290        300
DLGCQITIPK DGQKRKKSLR KKLDSLGKEK NKDKEFIPQA FGMPLSQVIA NDRAYKLKQD
       310        320        330        340        350        360
LQREEQKDAS SDFVSSLLPF GNKKQNKELS SSNSSLSSTS ETPNESTSPN TPEPAPRARR
       370        380        390        400        410        420
RGAMSVDSIT DLDDNQSRLL EALQLSLPAE AQSKKEKARD KKLSLNPIYR QVPRLVDSCC
       430        440        450        460        470        480
QHLEKHGLQT VGIFRVGSSK KRVRQLREEF DRGVDVCLEE EHSVHDVAAL LKEFLRDMPD
       490        500        510        520        530        540
PLLTRELYTA FINTLLLEPE EQLGTLQLLI YLLPPCNCDT LHRLLQFLSI VARHADDNVS
       550        560        570        580        590        600
KDGQEVTGNK MTSLNLATIF GPNLLHKQKS SDKEYSVQSS ARAEESTAII AVVQKMIENY
       610        620        630        640        650        660
EALFMVPPDL QNEVLISLLE TDPDVVDYLL RRKASQSSSP DILQTEVSFS MGGRHSSTDS
       670        680        690        700        710        720
NKASSGDISP YDNNSPVLSE RSLLAMQEDR ARGGSEKLYK VPEQYTLVGH LSSPKSKSRE
       730        740        750        760        770        780
SSPGPRLGKE MSEEPFNIWG TWHSTLKSGS KDPGMTGSYG DIFESSSLRP RPCSLSQGNL
       790        800        810        820        830        840
SLNWPRCQGS PTGLDSGTQV IRRTQTAATV EQCSVHLPVS RVCSTPHIQD GSRGTRRPAA
       850        860        870        880        890        900
SSDPFLSLNS TEDLAEGKED VAWLQSQARP VYQRPQESGK DDRRPPPPYP GSGKPATTSA
       910        920        930        940        950        960
QLPLEPPLWR LQRHEEGSET AVEGGQQASG EHQTRPKKLS SAYSLSASEQ DKQNLGEASW
       970        980
LDWQRERWQI WELLSTDNPD ALPETLV

Isoforms

- Isoform 2 of Rho GTPase-activating protein 6 - Isoform 3 of Rho GTPase-activating protein 6 - Isoform 4 of Rho GTPase-activating protein 6

Sequence View

        10         20         30         40         50         60
MSAQSLLHSV FSCSSPASGG TASAKGFSKR KLRQTRSLDP ALIGGCGSEM GAEGGLRGST
        70         80         90        100        110        120
VSRLHSPQLL AEGLGSRLAS SPRSQHLRAT RFQTPRPLCS SFSTPSTPQE KSPSGSFHFD
       130        140        150        160        170        180
YEVPLSRSGL KKSMAWDLPS VLAGSGSASS RSPASILSSS GGGPNGIFSS PRRWLQQRKF
       190        200        210        220        230        240
QPPPNSRSHP YVVWRSEGDF TWNSMSGRSV RLRSVPIQSL SELERARLQE VAFYQLQQDC
       250        260        270        280        290        300
DLGCQITIPK DGQKRKKSLR KKLDSLGKEK NKDKEFIPQA FGMPLSQVIA NDRAYKLKQD
       310        320        330        340        350        360
LQREEQKDAS SDFVSSLLPF GNKKQNKELS SSNSSLSSTS ETPNESTSPN TPEPAPRARR
       370        380        390        400        410        420
RGAMSVDSIT DLDDNQSRLL EALQLSLPAE AQSKKEKARD KKLSLNPIYR QVPRLVDSCC
       430        440        450        460        470        480
QHLEKHGLQT VGIFRVGSSK KRVRQLREEF DRGVDVCLEE EHSVHDVAAL LKEFLRDMPD
       490        500        510        520        530        540
PLLTRELYTA FINTLLLEPE EQLGTLQLLI YLLPPCNCDT LHRLLQFLSI VARHADDNVS
       550        560        570        580        590        600
KDGQEVTGNK MTSLNLATIF GPNLLHKQKS SDKEYSVQSS ARAEESTAII AVVQKMIENY
       610        620        630        640        650        660
EALFMVPPDL QNEVLISLLE TDPDVVDYLL RRKASQSSSP DILQTEVSFS MGGRHSSTDS
       670        680        690        700        710        720
NKASSGDISP YDNNSPVLSE RSLLAMQEDR ARGGSEKLYK VPEQYTLVGH LSSPKSKSRE
       730        740        750        760        770        780
SSPGPRLGKE MSEEPFNIWG TWHSTLKSGS KDPGMTGSYG DIFESSSLRP RPCSLSQGNL
       790        800        810        820        830        840
SLNWPRCQGS PTGLDSGTQV IRRTQTAATV EQCSVHLPVS RVCSTPHIQD GSRGTRRPAA
       850        860        870        880        890        900
SSDPFLSLNS TEDLAEGKED VAWLQSQARP VYQRPQESGK DDRRPPPPYP GSGKPATTSA
       910        920        930        940        950        960
QLPLEPPLWR LQRHEEGSET AVEGGQQASG EHQTRPKKLS SAYSLSASEQ DKQNLGEASW
       970        980
LDWQRERWQI WELLSTDNPD ALPETLV         10         20         30         40         50         60
MSAQSLLHSV FSCSSPASGG TASAKGFSKR KLRQTRSLDP ALIGGCGSEM GAEGGLRGST
        70         80         90        100        110        120
VSRLHSPQLL AEGLGSRLAS SPRSQHLRAT RFQTPRPLCS SFSTPSTPQE KSPSGSFHFD
       130        140        150        160        170        180
YEVPLSRSGL KKSMAWDLPS VLAGSGSASS RSPASILSSS GGGPNGIFSS PRRWLQQRKF
       190        200        210        220        230        240
QPPPNSRSHP YVVWRSEGDF TWNSMSGRSV RLRSVPIQSL SELERARLQE VAFYQLQQDC
       250        260        270        280        290        300
DLGCQITIPK DGQKRKKSLR KKLDSLGKEK NKDKEFIPQA FGMPLSQVIA NDRAYKLKQD
       310        320        330        340        350        360
LQREEQKDAS SDFVSSLLPF GNKKQNKELS SSNSSLSSTS ETPNESTSPN TPEPAPRARR
       370        380        390        400        410        420
RGAMSVDSIT DLDDNQSRLL EALQLSLPAE AQSKKEKARD KKLSLNPIYR QVPRLVDSCC
       430        440        450        460        470        480
QHLEKHGLQT VGIFRVGSSK KRVRQLREEF DRGVDVCLEE EHSVHDVAAL LKEFLRDMPD
       490        500        510        520        530        540
PLLTRELYTA FINTLLLEPE EQLGTLQLLI YLLPPCNCDT LHRLLQFLSI VARHADDNVS
       550        560        570        580        590        600
KDGQEVTGNK MTSLNLATIF GPNLLHKQKS SDKEYSVQSS ARAEESTAII AVVQKMIENY
       610        620        630        640        650        660
EALFMVPPDL QNEVLISLLE TDPDVVDYLL RRKASQSSSP DILQTEVSFS MGGRHSSTDS
       670        680        690        700        710        720
NKASSGDISP YDNNSPVLSE RSLLAMQEDR ARGGSEKLYK VPEQYTLVGH LSSPKSKSRE
       730        740        750        760        770        780
SSPGPRLGKE MSEEPFNIWG TWHSTLKSGS KDPGMTGSYG DIFESSSLRP RPCSLSQGNL
       790        800        810        820        830        840
SLNWPRCQGS PTGLDSGTQV IRRTQTAATV EQCSVHLPVS RVCSTPHIQD GSRGTRRPAA
       850        860        870        880        890        900
SSDPFLSLNS TEDLAEGKED VAWLQSQARP VYQRPQESGK DDRRPPPPYP GSGKPATTSA
       910        920        930        940        950        960
QLPLEPPLWR LQRHEEGSET AVEGGQQASG EHQTRPKKLS SAYSLSASEQ DKQNLGEASW
       970        980
LDWQRERWQI WELLSTDNPD ALPETLV         10         20         30         40         50         60
MSAQSLLHSV FSCSSPASGG TASAKGFSKR KLRQTRSLDP ALIGGCGSEM GAEGGLRGST
        70         80         90        100        110        120
VSRLHSPQLL AEGLGSRLAS SPRSQHLRAT RFQTPRPLCS SFSTPSTPQE KSPSGSFHFD
       130        140        150        160        170        180
YEVPLSRSGL KKSMAWDLPS VLAGSGSASS RSPASILSSS GGGPNGIFSS PRRWLQQRKF
       190        200        210        220        230        240
QPPPNSRSHP YVVWRSEGDF TWNSMSGRSV RLRSVPIQSL SELERARLQE VAFYQLQQDC
       250        260        270        280        290        300
DLGCQITIPK DGQKRKKSLR KKLDSLGKEK NKDKEFIPQA FGMPLSQVIA NDRAYKLKQD
       310        320        330        340        350        360
LQREEQKDAS SDFVSSLLPF GNKKQNKELS SSNSSLSSTS ETPNESTSPN TPEPAPRARR
       370        380        390        400        410        420
RGAMSVDSIT DLDDNQSRLL EALQLSLPAE AQSKKEKARD KKLSLNPIYR QVPRLVDSCC
       430        440        450        460        470        480
QHLEKHGLQT VGIFRVGSSK KRVRQLREEF DRGVDVCLEE EHSVHDVAAL LKEFLRDMPD
       490        500        510        520        530        540
PLLTRELYTA FINTLLLEPE EQLGTLQLLI YLLPPCNCDT LHRLLQFLSI VARHADDNVS
       550        560        570        580        590        600
KDGQEVTGNK MTSLNLATIF GPNLLHKQKS SDKEYSVQSS ARAEESTAII AVVQKMIENY
       610        620        630        640        650        660
EALFMVPPDL QNEVLISLLE TDPDVVDYLL RRKASQSSSP DILQTEVSFS MGGRHSSTDS
       670        680        690        700        710        720
NKASSGDISP YDNNSPVLSE RSLLAMQEDR ARGGSEKLYK VPEQYTLVGH LSSPKSKSRE
       730        740        750        760        770        780
SSPGPRLGKE MSEEPFNIWG TWHSTLKSGS KDPGMTGSYG DIFESSSLRP RPCSLSQGNL
       790        800        810        820        830        840
SLNWPRCQGS PTGLDSGTQV IRRTQTAATV EQCSVHLPVS RVCSTPHIQD GSRGTRRPAA
       850        860        870        880        890        900
SSDPFLSLNS TEDLAEGKED VAWLQSQARP VYQRPQESGK DDRRPPPPYP GSGKPATTSA
       910        920        930        940        950        960
QLPLEPPLWR LQRHEEGSET AVEGGQQASG EHQTRPKKLS SAYSLSASEQ DKQNLGEASW
       970        980
LDWQRERWQI WELLSTDNPD ALPETLV

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
O54834-1-unknown	MSAQSL...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O54834-1-unknown	MSAQSL...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt87590
O54834-388-unknown	PAEAQS...	388	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29539
O54834-388-unknown	PAEAQS...	388	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt146464
O54834-388-unknown	PAEAQS...	388	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt146757
O54834-388-unknown	PAEAQS...	388	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt151803

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LQLSLP	387	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29539
...LQLSLP	387	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129771
...LQLSLP	387	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt130068
...LQLSLP	387	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt135207
...PETLV	987	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...PETLV	987	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83210
...PETLV	987	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83209

TopFIND

O54834: Rho GTPase-activating protein 6

General Information

2

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates