TopFIND 4.0

O54902: Natural resistance-associated macrophage protein 2

General Information

Protein names
- Natural resistance-associated macrophage protein 2
- NRAMP 2
- Divalent cation transporter 1
- Divalent metal transporter 1
- DMT-1
- Solute carrier family 11 member 2
Gene names Slc11a2
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID O54902

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MVLDPEEKIP DDGASGDHGD SASLGAINPA YSNSSLPHST GDSEEPFTTY FDEKIPIPEE 
        70         80         90        100        110        120 
EYSCFSFRKL WAFTGPGFLM SIAYLDPGNI ESDLQSGAVA GFKLLWVLLL ATIVGLLLQR 
       130        140        150        160        170        180 
LAARLGVVTG LHLAEVCHRQ YPKVPRIILW LMVELAIIGS DMQEVIGSAI AINLLSAGRV 
       190        200        210        220        230        240 
PLYGGVLITI ADTFVFLFLD KYGLRKLEAF FGFLITIMAL TFGYEYVTVK PSQSQVLRGM 
       250        260        270        280        290        300 
FVPSCSGCHT PQVEQAVGIV GAVIMPHNMY LHSALVKSRQ VNRANKQEVR EANKYFFIES 
       310        320        330        340        350        360 
CIALFVSFII NVFVVSVFAE AFFEKTNEQV VEVCRNSSSP HADLFPNDNS TLAVDIYKGG 
       370        380        390        400        410        420 
VVLGCYFGPA ALYIWAVGIL AAGQSSTMTG TYSGQFVMEG FLNLKWSRFA RVILTRSIAI 
       430        440        450        460        470        480 
IPTLLVAVFQ DVEHLTGMND FLNVLQSLQL PFALIPILTF TSLRPVMSEF SNGIGWRIAG 
       490        500        510        520        530        540 
GILVLLVCSI NMYFVVVYVQ ELGHVALYVV AAVVSVAYLG FVFYLGWQCL IALGLSFLDC 
       550        560    
GRSYHLGLTA RPEIYLLNTV DAVSLVSR

Isoforms

- Isoform 1 of Natural resistance-associated macrophage protein 2

Sequence View

        10         20         30         40         50         60 
MVLDPEEKIP DDGASGDHGD SASLGAINPA YSNSSLPHST GDSEEPFTTY FDEKIPIPEE 
        70         80         90        100        110        120 
EYSCFSFRKL WAFTGPGFLM SIAYLDPGNI ESDLQSGAVA GFKLLWVLLL ATIVGLLLQR 
       130        140        150        160        170        180 
LAARLGVVTG LHLAEVCHRQ YPKVPRIILW LMVELAIIGS DMQEVIGSAI AINLLSAGRV 
       190        200        210        220        230        240 
PLYGGVLITI ADTFVFLFLD KYGLRKLEAF FGFLITIMAL TFGYEYVTVK PSQSQVLRGM 
       250        260        270        280        290        300 
FVPSCSGCHT PQVEQAVGIV GAVIMPHNMY LHSALVKSRQ VNRANKQEVR EANKYFFIES 
       310        320        330        340        350        360 
CIALFVSFII NVFVVSVFAE AFFEKTNEQV VEVCRNSSSP HADLFPNDNS TLAVDIYKGG 
       370        380        390        400        410        420 
VVLGCYFGPA ALYIWAVGIL AAGQSSTMTG TYSGQFVMEG FLNLKWSRFA RVILTRSIAI 
       430        440        450        460        470        480 
IPTLLVAVFQ DVEHLTGMND FLNVLQSLQL PFALIPILTF TSLRPVMSEF SNGIGWRIAG 
       490        500        510        520        530        540 
GILVLLVCSI NMYFVVVYVQ ELGHVALYVV AAVVSVAYLG FVFYLGWQCL IALGLSFLDC 
       550        560    
GRSYHLGLTA RPEIYLLNTV DAVSLVSR



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O54902-1-unknown MVLDPE... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    O54902-1-unknown MVLDPE... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt193100

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...SLVSR 568 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)