TopFIND 4.0

O54915: Nuclear receptor subfamily 1 group I member 2

General Information

Protein names
- Nuclear receptor subfamily 1 group I member 2
- Orphan nuclear receptor PXR
- Pregnane X receptor
Gene names Nr1i2
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID O54915

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MRPEESWSRV GLVQCEEADS ALEEPINVEE EDGGLQICRV CGDKANGYHF NVMTCEGCKG 
        70         80         90        100        110        120 
FFRRAMKRNV RLRCPFRKGT CEITRKTRRQ CQACRLRKCL ESGMKKEMIM SDAAVEQRRA 
       130        140        150        160        170        180 
LIKRKKREKI EAPPPGGQGL TEEQQALIQE LMDAQMQTFD TTFSHFKDFR LPAVFHSGCE 
       190        200        210        220        230        240 
LPEFLQASLL EDPATWSQIM KDRVPMKISL QLRGEDGSIW NYQPPSKSDG KEIIPLLPHL 
       250        260        270        280        290        300 
ADVSTYMFKG VINFAKVISY FRDLPIEDQI SLLKGATFEM CILRFNTMFD TETGTWECGR 
       310        320        330        340        350        360 
LAYCFEDPNG GFQKLLLDPL MKFHCMLKKL QLHKEEYVLM QAISLFSPDR PGVVQRSVVD 
       370        380        390        400        410        420 
QLQERFALTL KAYIECSRPY PAHRFLFLKI MAVLTELRSI NAQQTQQLLR IQDSHPFATP 
       430    
LMQELFSSTD G

Isoforms

- Isoform 2 of Nuclear receptor subfamily 1 group I member 2

Sequence View

        10         20         30         40         50         60 
MRPEESWSRV GLVQCEEADS ALEEPINVEE EDGGLQICRV CGDKANGYHF NVMTCEGCKG 
        70         80         90        100        110        120 
FFRRAMKRNV RLRCPFRKGT CEITRKTRRQ CQACRLRKCL ESGMKKEMIM SDAAVEQRRA 
       130        140        150        160        170        180 
LIKRKKREKI EAPPPGGQGL TEEQQALIQE LMDAQMQTFD TTFSHFKDFR LPAVFHSGCE 
       190        200        210        220        230        240 
LPEFLQASLL EDPATWSQIM KDRVPMKISL QLRGEDGSIW NYQPPSKSDG KEIIPLLPHL 
       250        260        270        280        290        300 
ADVSTYMFKG VINFAKVISY FRDLPIEDQI SLLKGATFEM CILRFNTMFD TETGTWECGR 
       310        320        330        340        350        360 
LAYCFEDPNG GFQKLLLDPL MKFHCMLKKL QLHKEEYVLM QAISLFSPDR PGVVQRSVVD 
       370        380        390        400        410        420 
QLQERFALTL KAYIECSRPY PAHRFLFLKI MAVLTELRSI NAQQTQQLLR IQDSHPFATP 
       430    
LMQELFSSTD G



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O54915-1-unknown MRPEES... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    O54915-1-unknown MRPEES... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt83193

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...SSTDG 431 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...SSTDG 431 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt78811

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)