TopFIND 4.0

O55060: Thiopurine S-methyltransferase {ECO:0000303|PubMed:18484748}

General Information

Protein names
- Thiopurine S-methyltransferase {ECO:0000303|PubMed:18484748}
- 2.1.1.67 {ECO:0000269|PubMed:18484748}
- Thiopurine methyltransferase

Gene names Tpmt
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID O55060

1

N-termini

3

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSLDMKEHPD AEVQKNQVLT LEDWKEKWVT RHISFHQEQG HQLLKKHLDT FLKGQSGLRV 
        70         80         90        100        110        120 
FFPLCGKAIE MKWFADRGHT VVGVEISEIG IREFFAEQNL SYTEEPLAEI AGAKVFKSSS 
       130        140        150        160        170        180 
GSISLYCCSI FDLPRANIGK FDRIWDRGAL VAINPGDHDR YADIILSLLR KEFQYLVAVL 
       190        200        210        220        230        240 
SYDPTKHAGP PFYVPSAELK RLFGTKCSMQ CLEEVDALEE RHKAWGLDYL FEKLYLLTEK 
   

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O55060-1-unknown MSLDMK... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)