TopFIND 4.0

O55176: E3 ubiquitin-protein ligase Praja-1

General Information

Protein names
- E3 ubiquitin-protein ligase Praja-1
- Praja1
- 2.3.2.27
- RING-type E3 ubiquitin transferase Praja-1 {ECO:0000305}
Gene names Pja1
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID O55176

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSHQERIASQ RRTTAEVPMH RSTANQSKRS RSPFASTRRR WDDSESSGAS LAVESEDYSR 
        70         80         90        100        110        120 
YPPREYRASG SRRGLAYGHI DTVVARDSEE EGAGPVDRLP VRGKAGKFKD DPEKGARSSR 
       130        140        150        160        170        180 
FTSVNHDAKE ECGKVESPPA ARCSARRAEL SKQNGSSASQ ISSAEGRAAA KGNNSLERER 
       190        200        210        220        230        240 
QNLPARPSRA PVSICGGGEN TPKSAEEPVV RPKVRNVATP NCMKPKVFFD TDDDDDVPHS 
       250        260        270        280        290        300 
TSRWRDAADA EEAHAEGLAR RGRGEAASSS EPRYAEDQDA RSEQAKADKV PRRRRTMADP 
       310        320        330        340        350        360 
DFWAYTDDYY RYYEEDSDSD KEWMAALRRK YRSREQPQSS SGESWELLPG KEELERQQAG 
       370        380        390        400        410        420 
AGSLASAGSN GSGYPEEVQD PSLQEEEQAS LEEGEIPWLR YNENESSSEG DNESTHELIQ 
       430        440        450        460        470        480 
PGMFMLDGNN NLEDDSSVSE DLEVDWSLFD GFADGLGVAE AISYVDPQFL TYMALEERLA 
       490        500        510        520        530        540 
QAMETALAHL ESLAVDVEVA NPPASKESID ALPEILVTED HGAVGQEMCC PICCSEYVKG 
       550        560        570    
EVATELPCHH YFHKPCVSIW LQKSGTCPVC RCMFPPPL

Isoforms

- Isoform 2 of E3 ubiquitin-protein ligase Praja-1 - Isoform 3 of E3 ubiquitin-protein ligase Praja-1 - Isoform 4 of E3 ubiquitin-protein ligase Praja-1

Sequence View

        10         20         30         40         50         60 
MSHQERIASQ RRTTAEVPMH RSTANQSKRS RSPFASTRRR WDDSESSGAS LAVESEDYSR 
        70         80         90        100        110        120 
YPPREYRASG SRRGLAYGHI DTVVARDSEE EGAGPVDRLP VRGKAGKFKD DPEKGARSSR 
       130        140        150        160        170        180 
FTSVNHDAKE ECGKVESPPA ARCSARRAEL SKQNGSSASQ ISSAEGRAAA KGNNSLERER 
       190        200        210        220        230        240 
QNLPARPSRA PVSICGGGEN TPKSAEEPVV RPKVRNVATP NCMKPKVFFD TDDDDDVPHS 
       250        260        270        280        290        300 
TSRWRDAADA EEAHAEGLAR RGRGEAASSS EPRYAEDQDA RSEQAKADKV PRRRRTMADP 
       310        320        330        340        350        360 
DFWAYTDDYY RYYEEDSDSD KEWMAALRRK YRSREQPQSS SGESWELLPG KEELERQQAG 
       370        380        390        400        410        420 
AGSLASAGSN GSGYPEEVQD PSLQEEEQAS LEEGEIPWLR YNENESSSEG DNESTHELIQ 
       430        440        450        460        470        480 
PGMFMLDGNN NLEDDSSVSE DLEVDWSLFD GFADGLGVAE AISYVDPQFL TYMALEERLA 
       490        500        510        520        530        540 
QAMETALAHL ESLAVDVEVA NPPASKESID ALPEILVTED HGAVGQEMCC PICCSEYVKG 
       550        560        570    
EVATELPCHH YFHKPCVSIW LQKSGTCPVC RCMFPPPL         10         20         30         40         50         60 
MSHQERIASQ RRTTAEVPMH RSTANQSKRS RSPFASTRRR WDDSESSGAS LAVESEDYSR 
        70         80         90        100        110        120 
YPPREYRASG SRRGLAYGHI DTVVARDSEE EGAGPVDRLP VRGKAGKFKD DPEKGARSSR 
       130        140        150        160        170        180 
FTSVNHDAKE ECGKVESPPA ARCSARRAEL SKQNGSSASQ ISSAEGRAAA KGNNSLERER 
       190        200        210        220        230        240 
QNLPARPSRA PVSICGGGEN TPKSAEEPVV RPKVRNVATP NCMKPKVFFD TDDDDDVPHS 
       250        260        270        280        290        300 
TSRWRDAADA EEAHAEGLAR RGRGEAASSS EPRYAEDQDA RSEQAKADKV PRRRRTMADP 
       310        320        330        340        350        360 
DFWAYTDDYY RYYEEDSDSD KEWMAALRRK YRSREQPQSS SGESWELLPG KEELERQQAG 
       370        380        390        400        410        420 
AGSLASAGSN GSGYPEEVQD PSLQEEEQAS LEEGEIPWLR YNENESSSEG DNESTHELIQ 
       430        440        450        460        470        480 
PGMFMLDGNN NLEDDSSVSE DLEVDWSLFD GFADGLGVAE AISYVDPQFL TYMALEERLA 
       490        500        510        520        530        540 
QAMETALAHL ESLAVDVEVA NPPASKESID ALPEILVTED HGAVGQEMCC PICCSEYVKG 
       550        560        570    
EVATELPCHH YFHKPCVSIW LQKSGTCPVC RCMFPPPL         10         20         30         40         50         60 
MSHQERIASQ RRTTAEVPMH RSTANQSKRS RSPFASTRRR WDDSESSGAS LAVESEDYSR 
        70         80         90        100        110        120 
YPPREYRASG SRRGLAYGHI DTVVARDSEE EGAGPVDRLP VRGKAGKFKD DPEKGARSSR 
       130        140        150        160        170        180 
FTSVNHDAKE ECGKVESPPA ARCSARRAEL SKQNGSSASQ ISSAEGRAAA KGNNSLERER 
       190        200        210        220        230        240 
QNLPARPSRA PVSICGGGEN TPKSAEEPVV RPKVRNVATP NCMKPKVFFD TDDDDDVPHS 
       250        260        270        280        290        300 
TSRWRDAADA EEAHAEGLAR RGRGEAASSS EPRYAEDQDA RSEQAKADKV PRRRRTMADP 
       310        320        330        340        350        360 
DFWAYTDDYY RYYEEDSDSD KEWMAALRRK YRSREQPQSS SGESWELLPG KEELERQQAG 
       370        380        390        400        410        420 
AGSLASAGSN GSGYPEEVQD PSLQEEEQAS LEEGEIPWLR YNENESSSEG DNESTHELIQ 
       430        440        450        460        470        480 
PGMFMLDGNN NLEDDSSVSE DLEVDWSLFD GFADGLGVAE AISYVDPQFL TYMALEERLA 
       490        500        510        520        530        540 
QAMETALAHL ESLAVDVEVA NPPASKESID ALPEILVTED HGAVGQEMCC PICCSEYVKG 
       550        560        570    
EVATELPCHH YFHKPCVSIW LQKSGTCPVC RCMFPPPL



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)