TopFIND 4.0

O60239: SH3 domain-binding protein 5

General Information

Protein names
- SH3 domain-binding protein 5
- SH3BP-5
- SH3 domain-binding protein that preferentially associates with BTK
Gene names SH3BP5
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID O60239

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDAALKRSRS EEPAEILPPA RDEEEEEEEG MEQGLEEEEE VDPRIQGELE KLNQSTDDIN 
        70         80         90        100        110        120 
RRETELEDAR QKFRSVLVEA TVKLDELVKK IGKAVEDSKP YWEARRVARQ AQLEAQKATQ 
       130        140        150        160        170        180 
DFQRATEVLR AAKETISLAE QRLLEDDKRQ FDSAWQEMLN HATQRVMEAE QTKTRSELVH 
       190        200        210        220        230        240 
KETAARYNAA MGRMRQLEKK LKRAINKSKP YFELKAKYYV QLEQLKKTVD DLQAKLTLAK 
       250        260        270        280        290        300 
GEYKMALKNL EMISDEIHER RRSSAMGPRG CGVGAEGSST SVEDLPGSKP EPDAISVASE 
       310        320        330        340        350        360 
AFEDDSCSNF VSEDDSETQS VSSFSSGPTS PSEMPDQFPA VVRPGSLDLP SPVSLSEFGM 
       370        380        390        400        410        420 
MFPVLGPRSE CSGASSPECE VERGDRAEGA ENKTSDKANN NRGLSSSSGS GGSSKSQSST 
       430        440        450    
SPEGQALENR MKQLSLQCSK GRDGIIADIK MVQIG

Isoforms

- Isoform 2 of SH3 domain-binding protein 5

Sequence View

        10         20         30         40         50         60 
MDAALKRSRS EEPAEILPPA RDEEEEEEEG MEQGLEEEEE VDPRIQGELE KLNQSTDDIN 
        70         80         90        100        110        120 
RRETELEDAR QKFRSVLVEA TVKLDELVKK IGKAVEDSKP YWEARRVARQ AQLEAQKATQ 
       130        140        150        160        170        180 
DFQRATEVLR AAKETISLAE QRLLEDDKRQ FDSAWQEMLN HATQRVMEAE QTKTRSELVH 
       190        200        210        220        230        240 
KETAARYNAA MGRMRQLEKK LKRAINKSKP YFELKAKYYV QLEQLKKTVD DLQAKLTLAK 
       250        260        270        280        290        300 
GEYKMALKNL EMISDEIHER RRSSAMGPRG CGVGAEGSST SVEDLPGSKP EPDAISVASE 
       310        320        330        340        350        360 
AFEDDSCSNF VSEDDSETQS VSSFSSGPTS PSEMPDQFPA VVRPGSLDLP SPVSLSEFGM 
       370        380        390        400        410        420 
MFPVLGPRSE CSGASSPECE VERGDRAEGA ENKTSDKANN NRGLSSSSGS GGSSKSQSST 
       430        440        450    
SPEGQALENR MKQLSLQCSK GRDGIIADIK MVQIG



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O60239-1-unknown MDAALK... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    O60239-158-unknown MLNHAT... 158 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt65766

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...MVQIG 455 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...MVQIG 455 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt61384

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)