O60266: Adenylate cyclase type 3

General Information

Protein names	- Adenylate cyclase type 3 - 4.6.1.1 - ATP pyrophosphate-lyase 3 - Adenylate cyclase type III - AC-III - Adenylate cyclase, olfactive type - Adenylyl cyclase 3 {ECO:0000305} - AC3 {ECO:0000303\|PubMed:9920776}
Gene names	ADCY3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O60266

5 N-termini

6 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPRNQGFSEP EYSAEYSAEY SVSLPSDPDR GVGRTHEISV RNSGSCLCLP RFMRLTFVPE
        70         80         90        100        110        120
SLENLYQTYF KRQRHETLLV LVVFAALFDC YVVVMCAVVF SSDKLASLAV AGIGLVLDII
       130        140        150        160        170        180
LFVLCKKGLL PDRVTRRVLP YVLWLLITAQ IFSYLGLNFA RAHAASDTVG WQVFFVFSFF
       190        200        210        220        230        240
ITLPLSLSPI VIISVVSCVV HTLVLGVTVA QQQQEELKGM QLLREILANV FLYLCAIAVG
       250        260        270        280        290        300
IMSYYMADRK HRKAFLEARQ SLEVKMNLEE QSQQQENLML SILPKHVADE MLKDMKKDES
       310        320        330        340        350        360
QKDQQQFNTM YMYRHENVSI LFADIVGFTQ LSSACSAQEL VKLLNELFAR FDKLAAKYHQ
       370        380        390        400        410        420
LRIKILGDCY YCICGLPDYR EDHAVCSILM GLAMVEAISY VREKTKTGVD MRVGVHTGTV
       430        440        450        460        470        480
LGGVLGQKRW QYDVWSTDVT VANKMEAGGI PGRVHISQST MDCLKGEFDV EPGDGGSRCD
       490        500        510        520        530        540
YLEEKGIETY LIIASKPEVK KTATQNGLNG SALPNGAPAS SKSSSPALIE TKEPNGSAHS
       550        560        570        580        590        600
SGSTSEKPEE QDAQADNPSF PNPRRRLRLQ DLADRVVDAS EDEHELNQLL NEALLERESA
       610        620        630        640        650        660
QVVKKRNTFL LSMRFMDPEM ETRYSVEKEK QSGAAFSCSC VVLLCTALVE ILIDPWLMTN
       670        680        690        700        710        720
YVTFMVGEIL LLILTICSLA AIFPRAFPKK LVAFSTWIDR TRWARNTWAM LAIFILVMAN
       730        740        750        760        770        780
VVDMLSCLQY YTGPSNATAG METEGSCLEN PKYYNYVAVL SLIATIMLVQ VSHMVKLTLM
       790        800        810        820        830        840
LLVAGAVATI NLYAWRPVFD EYDHKRFREH DLPMVALEQM QGFNPGLNGT DRLPLVPSKY
       850        860        870        880        890        900
SMTVMVFLMM LSFYYFSRHV EKLARTLFLW KIEVHDQKER VYEMRRWNEA LVTNMLPEHV
       910        920        930        940        950        960
ARHFLGSKKR DEELYSQTYD EIGVMFASLP NFADFYTEES INNGGIECLR FLNEIISDFD
       970        980        990       1000       1010       1020
SLLDNPKFRV ITKIKTIGST YMAASGVTPD VNTNGFASSN KEDKSERERW QHLADLADFA
      1030       1040       1050       1060       1070       1080
LAMKDTLTNI NNQSFNNFML RIGMNKGGVL AGVIGARKPH YDIWGNTVNV ASRMESTGVM
      1090       1100       1110       1120       1130       1140
GNIQVVEETQ VILREYGFRF VRRGPIFVKG KGELLTFFLK GRDKLATFPN GPSVTLPHQV

VDNS

Isoforms

- Isoform 2 of Adenylate cyclase type 3

Sequence View

        10         20         30         40         50         60
MPRNQGFSEP EYSAEYSAEY SVSLPSDPDR GVGRTHEISV RNSGSCLCLP RFMRLTFVPE
        70         80         90        100        110        120
SLENLYQTYF KRQRHETLLV LVVFAALFDC YVVVMCAVVF SSDKLASLAV AGIGLVLDII
       130        140        150        160        170        180
LFVLCKKGLL PDRVTRRVLP YVLWLLITAQ IFSYLGLNFA RAHAASDTVG WQVFFVFSFF
       190        200        210        220        230        240
ITLPLSLSPI VIISVVSCVV HTLVLGVTVA QQQQEELKGM QLLREILANV FLYLCAIAVG
       250        260        270        280        290        300
IMSYYMADRK HRKAFLEARQ SLEVKMNLEE QSQQQENLML SILPKHVADE MLKDMKKDES
       310        320        330        340        350        360
QKDQQQFNTM YMYRHENVSI LFADIVGFTQ LSSACSAQEL VKLLNELFAR FDKLAAKYHQ
       370        380        390        400        410        420
LRIKILGDCY YCICGLPDYR EDHAVCSILM GLAMVEAISY VREKTKTGVD MRVGVHTGTV
       430        440        450        460        470        480
LGGVLGQKRW QYDVWSTDVT VANKMEAGGI PGRVHISQST MDCLKGEFDV EPGDGGSRCD
       490        500        510        520        530        540
YLEEKGIETY LIIASKPEVK KTATQNGLNG SALPNGAPAS SKSSSPALIE TKEPNGSAHS
       550        560        570        580        590        600
SGSTSEKPEE QDAQADNPSF PNPRRRLRLQ DLADRVVDAS EDEHELNQLL NEALLERESA
       610        620        630        640        650        660
QVVKKRNTFL LSMRFMDPEM ETRYSVEKEK QSGAAFSCSC VVLLCTALVE ILIDPWLMTN
       670        680        690        700        710        720
YVTFMVGEIL LLILTICSLA AIFPRAFPKK LVAFSTWIDR TRWARNTWAM LAIFILVMAN
       730        740        750        760        770        780
VVDMLSCLQY YTGPSNATAG METEGSCLEN PKYYNYVAVL SLIATIMLVQ VSHMVKLTLM
       790        800        810        820        830        840
LLVAGAVATI NLYAWRPVFD EYDHKRFREH DLPMVALEQM QGFNPGLNGT DRLPLVPSKY
       850        860        870        880        890        900
SMTVMVFLMM LSFYYFSRHV EKLARTLFLW KIEVHDQKER VYEMRRWNEA LVTNMLPEHV
       910        920        930        940        950        960
ARHFLGSKKR DEELYSQTYD EIGVMFASLP NFADFYTEES INNGGIECLR FLNEIISDFD
       970        980        990       1000       1010       1020
SLLDNPKFRV ITKIKTIGST YMAASGVTPD VNTNGFASSN KEDKSERERW QHLADLADFA
      1030       1040       1050       1060       1070       1080
LAMKDTLTNI NNQSFNNFML RIGMNKGGVL AGVIGARKPH YDIWGNTVNV ASRMESTGVM
      1090       1100       1110       1120       1130       1140
GNIQVVEETQ VILREYGFRF VRRGPIFVKG KGELLTFFLK GRDKLATFPN GPSVTLPHQV

VDNS

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
O60266-1-unknown	MPRNQG...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O60266-235-unknown	CAIAVG...	235	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000399275
O60266-330-unknown	QLSSAC...	330	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000475652
O60266-390-unknown	MGLAMV...	390	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000384484
O60266-662-unknown	VTFMVG...	662	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000402008

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LAVAGI	112	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000406153
...CICGLP	376	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000401455
...LIETKE	532	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000389799
...AHSSGS	542	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000399275
...YYFSRH	858	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000402008
...VVDNS	1144	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

TopFIND

O60266: Adenylate cyclase type 3

General Information

5

N-termini

6

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

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Methodology:

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Protein Neighborhood

Domains & Features

5 N-termini - 6 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates