O60568: Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3
| Protein names | - Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 - Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 - 1.14.11.4 {ECO:0000269|PubMed:12475640, ECO:0000269|PubMed:18298658, ECO:0000269|PubMed:18834968, ECO:0000269|PubMed:30089812, ECO:0000269|PubMed:9582318, ECO:0000269|PubMed:9724729} - Lysyl hydroxylase 3 {ECO:0000303|PubMed:9582318, ECO:0000303|PubMed:9724729} - LH3 {ECO:0000303|PubMed:10686427} - Procollagen glycosyltransferase - 2.4.1.50 {ECO:0000269|PubMed:12475640, ECO:0000269|PubMed:18298658, ECO:0000269|PubMed:18834968, ECO:0000269|PubMed:30089812} - 2.4.1.66 {ECO:0000269|PubMed:10934207, ECO:0000269|PubMed:11896059, ECO:0000269|PubMed:11956192, ECO:0000269|PubMed:12475640, ECO:0000269|PubMed:18298658, ECO:0000269|PubMed:18834968, ECO:0000269|PubMed:30089812} - Galactosylhydroxylysine-glucosyltransferase - Procollagen galactosyltransferase - Procollagen glucosyltransferase |
|---|---|
| Gene names | PLOD3 |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | O60568 |
1
N-termini
4
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MTSSGPGPRF LLLLPLLLPP AASASDRPRG RDPVNPEKLL VITVATAETE GYLRFLRSAE
70 80 90 100 110 120
FFNYTVRTLG LGEEWRGGDV ARTVGGGQKV RWLKKEMEKY ADREDMIIMF VDSYDVILAG
130 140 150 160 170 180
SPTELLKKFV QSGSRLLFSA ESFCWPEWGL AEQYPEVGTG KRFLNSGGFI GFATTIHQIV
190 200 210 220 230 240
RQWKYKDDDD DQLFYTRLYL DPGLREKLSL NLDHKSRIFQ NLNGALDEVV LKFDRNRVRI
250 260 270 280 290 300
RNVAYDTLPI VVHGNGPTKL QLNYLGNYVP NGWTPEGGCG FCNQDRRTLP GGQPPPRVFL
310 320 330 340 350 360
AVFVEQPTPF LPRFLQRLLL LDYPPDRVTL FLHNNEVFHE PHIADSWPQL QDHFSAVKLV
370 380 390 400 410 420
GPEEALSPGE ARDMAMDLCR QDPECEFYFS LDADAVLTNL QTLRILIEEN RKVIAPMLSR
430 440 450 460 470 480
HGKLWSNFWG ALSPDEYYAR SEDYVELVQR KRVGVWNVPY ISQAYVIRGD TLRMELPQRD
490 500 510 520 530 540
VFSGSDTDPD MAFCKSFRDK GIFLHLSNQH EFGRLLATSR YDTEHLHPDL WQIFDNPVDW
550 560 570 580 590 600
KEQYIHENYS RALEGEGIVE QPCPDVYWFP LLSEQMCDEL VAEMEHYGQW SGGRHEDSRL
610 620 630 640 650 660
AGGYENVPTV DIHMKQVGYE DQWLQLLRTY VGPMTESLFP GYHTKARAVM NFVVRYRPDE
670 680 690 700 710 720
QPSLRPHHDS STFTLNVALN HKGLDYEGGG CRFLRYDCVI SSPRKGWALL HPGRLTHYHE
730
GLPTTWGTRY IMVSFVDP
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
1 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| O60568-25-unknown | SDRPRG... | 25 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...LGEEWR | 75 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000416070 | |||
| ...FLNSGG | 167 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000407551 | |||
| ...ELPQRD | 479 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000407908 | |||
| ...SFVDP | 738 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|