TopFIND 4.0

O60729: Dual specificity protein phosphatase CDC14B

General Information

Protein names
- Dual specificity protein phosphatase CDC14B
- 3.1.3.16
- 3.1.3.48
- CDC14 cell division cycle 14 homolog B
Gene names CDC14B
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID O60729

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MKRKSERRSS WAAAPPCSRR CSSTSPGVKK IRSSTQQDPR RRDPQDDVYL DITDRLCFAI 
        70         80         90        100        110        120 
LYSRPKSASN VHYFSIDNEL EYENFYADFG PLNLAMVYRY CCKINKKLKS ITMLRKKIVH 
       130        140        150        160        170        180 
FTGSDQRKQA NAAFLVGCYM VIYLGRTPEE AYRILIFGET SYIPFRDAAY GSCNFYITLL 
       190        200        210        220        230        240 
DCFHAVKKAM QYGFLNFNSF NLDEYEHYEK AENGDLNWII PDRFIAFCGP HSRARLESGY 
       250        260        270        280        290        300 
HQHSPETYIQ YFKNHNVTTI IRLNKRMYDA KRFTDAGFDH HDLFFADGST PTDAIVKEFL 
       310        320        330        340        350        360 
DICENAEGAI AVHCKAGLGR TGTLIACYIM KHYRMTAAET IAWVRICRPG SVIGPQQQFL 
       370        380        390        400        410        420 
VMKQTNLWLE GDYFRQKLKG QENGQHRAAF SKLLSGVDDI SINGVENQDQ QEPEPYSDDD 
       430        440        450        460        470        480 
EINGVTQGDR LRALKSRRQS KTNAIPLTVI LQSSVQSCKT SEPNISGSAG ITKRTTRSAS 
       490    
RKSSVKSLSI SRTKTVLR

Isoforms

- Isoform 1 of Dual specificity protein phosphatase CDC14B - Isoform 3 of Dual specificity protein phosphatase CDC14B - Isoform 4 of Dual specificity protein phosphatase CDC14B - Isoform 5 of Dual specificity protein phosphatase CDC14B

Sequence View

        10         20         30         40         50         60 
MKRKSERRSS WAAAPPCSRR CSSTSPGVKK IRSSTQQDPR RRDPQDDVYL DITDRLCFAI 
        70         80         90        100        110        120 
LYSRPKSASN VHYFSIDNEL EYENFYADFG PLNLAMVYRY CCKINKKLKS ITMLRKKIVH 
       130        140        150        160        170        180 
FTGSDQRKQA NAAFLVGCYM VIYLGRTPEE AYRILIFGET SYIPFRDAAY GSCNFYITLL 
       190        200        210        220        230        240 
DCFHAVKKAM QYGFLNFNSF NLDEYEHYEK AENGDLNWII PDRFIAFCGP HSRARLESGY 
       250        260        270        280        290        300 
HQHSPETYIQ YFKNHNVTTI IRLNKRMYDA KRFTDAGFDH HDLFFADGST PTDAIVKEFL 
       310        320        330        340        350        360 
DICENAEGAI AVHCKAGLGR TGTLIACYIM KHYRMTAAET IAWVRICRPG SVIGPQQQFL 
       370        380        390        400        410        420 
VMKQTNLWLE GDYFRQKLKG QENGQHRAAF SKLLSGVDDI SINGVENQDQ QEPEPYSDDD 
       430        440        450        460        470        480 
EINGVTQGDR LRALKSRRQS KTNAIPLTVI LQSSVQSCKT SEPNISGSAG ITKRTTRSAS 
       490    
RKSSVKSLSI SRTKTVLR         10         20         30         40         50         60 
MKRKSERRSS WAAAPPCSRR CSSTSPGVKK IRSSTQQDPR RRDPQDDVYL DITDRLCFAI 
        70         80         90        100        110        120 
LYSRPKSASN VHYFSIDNEL EYENFYADFG PLNLAMVYRY CCKINKKLKS ITMLRKKIVH 
       130        140        150        160        170        180 
FTGSDQRKQA NAAFLVGCYM VIYLGRTPEE AYRILIFGET SYIPFRDAAY GSCNFYITLL 
       190        200        210        220        230        240 
DCFHAVKKAM QYGFLNFNSF NLDEYEHYEK AENGDLNWII PDRFIAFCGP HSRARLESGY 
       250        260        270        280        290        300 
HQHSPETYIQ YFKNHNVTTI IRLNKRMYDA KRFTDAGFDH HDLFFADGST PTDAIVKEFL 
       310        320        330        340        350        360 
DICENAEGAI AVHCKAGLGR TGTLIACYIM KHYRMTAAET IAWVRICRPG SVIGPQQQFL 
       370        380        390        400        410        420 
VMKQTNLWLE GDYFRQKLKG QENGQHRAAF SKLLSGVDDI SINGVENQDQ QEPEPYSDDD 
       430        440        450        460        470        480 
EINGVTQGDR LRALKSRRQS KTNAIPLTVI LQSSVQSCKT SEPNISGSAG ITKRTTRSAS 
       490    
RKSSVKSLSI SRTKTVLR         10         20         30         40         50         60 
MKRKSERRSS WAAAPPCSRR CSSTSPGVKK IRSSTQQDPR RRDPQDDVYL DITDRLCFAI 
        70         80         90        100        110        120 
LYSRPKSASN VHYFSIDNEL EYENFYADFG PLNLAMVYRY CCKINKKLKS ITMLRKKIVH 
       130        140        150        160        170        180 
FTGSDQRKQA NAAFLVGCYM VIYLGRTPEE AYRILIFGET SYIPFRDAAY GSCNFYITLL 
       190        200        210        220        230        240 
DCFHAVKKAM QYGFLNFNSF NLDEYEHYEK AENGDLNWII PDRFIAFCGP HSRARLESGY 
       250        260        270        280        290        300 
HQHSPETYIQ YFKNHNVTTI IRLNKRMYDA KRFTDAGFDH HDLFFADGST PTDAIVKEFL 
       310        320        330        340        350        360 
DICENAEGAI AVHCKAGLGR TGTLIACYIM KHYRMTAAET IAWVRICRPG SVIGPQQQFL 
       370        380        390        400        410        420 
VMKQTNLWLE GDYFRQKLKG QENGQHRAAF SKLLSGVDDI SINGVENQDQ QEPEPYSDDD 
       430        440        450        460        470        480 
EINGVTQGDR LRALKSRRQS KTNAIPLTVI LQSSVQSCKT SEPNISGSAG ITKRTTRSAS 
       490    
RKSSVKSLSI SRTKTVLR         10         20         30         40         50         60 
MKRKSERRSS WAAAPPCSRR CSSTSPGVKK IRSSTQQDPR RRDPQDDVYL DITDRLCFAI 
        70         80         90        100        110        120 
LYSRPKSASN VHYFSIDNEL EYENFYADFG PLNLAMVYRY CCKINKKLKS ITMLRKKIVH 
       130        140        150        160        170        180 
FTGSDQRKQA NAAFLVGCYM VIYLGRTPEE AYRILIFGET SYIPFRDAAY GSCNFYITLL 
       190        200        210        220        230        240 
DCFHAVKKAM QYGFLNFNSF NLDEYEHYEK AENGDLNWII PDRFIAFCGP HSRARLESGY 
       250        260        270        280        290        300 
HQHSPETYIQ YFKNHNVTTI IRLNKRMYDA KRFTDAGFDH HDLFFADGST PTDAIVKEFL 
       310        320        330        340        350        360 
DICENAEGAI AVHCKAGLGR TGTLIACYIM KHYRMTAAET IAWVRICRPG SVIGPQQQFL 
       370        380        390        400        410        420 
VMKQTNLWLE GDYFRQKLKG QENGQHRAAF SKLLSGVDDI SINGVENQDQ QEPEPYSDDD 
       430        440        450        460        470        480 
EINGVTQGDR LRALKSRRQS KTNAIPLTVI LQSSVQSCKT SEPNISGSAG ITKRTTRSAS 
       490    
RKSSVKSLSI SRTKTVLR



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Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...KTVLR 498 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...KTVLR 498 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt65183

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)